Category: clinical study retractions

Another Bulfone-Paus paper under review, this one in Blood

Blood tells Retraction Watch that they are reviewing a 1999 paper co-authored by Silvia Bulfone-Paus, who has already retracted 12 papers in other journals.

The study, “Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15,” has been cited 124 times, according to Thomson Scientific’s Web of Knowledge. Its corresponding author is Tiziana Musso, of the University of Turin.

Joerg Zwirner, over at the Abnormal Science blog, has a three-part series deconstructing what he says are the flaws in the paper. Zwirner points out a number of data duplications. As he notes: Continue reading Another Bulfone-Paus paper under review, this one in Blood

Borstel hit with more potential misconduct as managing director steps down amid questions of plagiarism

Peter Zabel/Borstel

Retraction Watch readers are likely to be familiar with Germany’s Research Center Borstel, because it is home to Silvia Bulfone-Paus, who has recently retracted 12 papers. Now it turns out that Borstel’s managing director, Peter Zabel — who was involved in the Bulfone-Paus investigation — has stepped down because of allegations of duplication of his own work.

According to a statement from Borstel, translated from German: Continue reading Borstel hit with more potential misconduct as managing director steps down amid questions of plagiarism

Bulfone-Paus saga continues: Her supporters and home institution exchange sharp letters

Silvia Bulfone-Paus

Retraction Watch readers may have been following the case of Silvia Bulfone-Paus, whose lab has been forced to retract 12 papers amid allegations of scientific misconduct. As is often true in such cases, the story doesn’t end with those retractions. We’ve just become aware of a fascinating exchange in March and April between Bulfone-Paus’s supporters and her home institution, Germany’s Research Center Borstel.

First, some background: Karin Wiebauer, a former post-doc in Bulfone-Paus’s lab, flagged the potential misconduct, in great detail, for Bulfone-Paus in a November 2009 email. (In fact, she had brought it to her attention years earlier.) But Bulfone-Paus did not tell Borstel officials about the allegations until late February 2010. Borstel’s investigation into Bulfone-Paus’s lab began in July 2010.

Once that began, a person referring to himself as “Marco Berns” began emailing officials, journalists, and others about the situation. Nature called that move a “smear campaign,” and the emails “libellous,” but in retrospect they — and Wiebauer’s analysis — appear to have been spot-on, based on the eventual report of the Borstel committee. That report — which found data manipulation by two of Bulfone-Paus’s post-docs — led the institute’s Scientific Advisory Board to ask for Bulfone-Paus’s resignation. She only tendered that a month later, after more pressure.

So, with that as a preamble: If we were to characterize the letter, which we’ve made available here, we’d call it a good example of “shoot the messenger.” It’s signed by 25 scientists, starting with Desmond Tobin of the University of Bradford in the UK and ending with Andrzej Slominski of the University of Tennessee. Continue reading Bulfone-Paus saga continues: Her supporters and home institution exchange sharp letters

Psychology Today apparently retracts Kanazawa piece on why black women are “rated less physically attractive”

Psychology Today has apparently yanked a blog post by London School of Economics evolutionary psychologist Satoshi Kanazawa that wondered why black women were considered less attractive than other women.

The post, titled “Why Are Black Women Rated Less Physically Attractive Than Other Women, But Black Men Are Rated Better Looking Than Other Men?” was posted yesterday and available here, but that page now returns a 503 error.

A number of people have archived the post, however, including a communications and media professional who blogs at Chic.Seven. Her pdf is available here.

The post uses data from Add Health, a federally funded study:

Add Health was developed in response to a mandate from the U.S. Congress to fund a study of adolescent health, and Waves I and II focus on the forces that may influence adolescents’ health and risk behaviors, including personal traits, families, friendships, romantic relationships, peer groups, schools, neighborhoods, and communities. As participants have aged into adulthood, however, the scientific goals of the study have expanded and evolved. Wave III, conducted when respondents were between 18 and 26 years old, focuses on how adolescent experiences and behaviors are related to decisions, behavior, and health outcomes in the transition to adulthood.

Excerpts of the post, which really needs the graphs Kanazawa included — available at Chic.Seven’s blog — to be remotely comprehensible: Continue reading Psychology Today apparently retracts Kanazawa piece on why black women are “rated less physically attractive”

Yes, Virginia, medical writers really do commit plagiarism, says a surgery retraction

Readers may recall a recent post on a study purporting to show that one of the best insurance policies against a retraction is to employ a medical writer. Well, a group of Iranian surgeons did just that. How’d it work out for them?

Of course, since you’re reading about this on Retraction Watch, you already know the answer to that one, don’t you?

The World Journal of Surgery has retracted a 2010 article written by hired guns who apparently decided to perform wordthievery rather than wordsmithery.

Here’s the notice (stated, oddly, as an “erratum” to the original paper): Continue reading Yes, Virginia, medical writers really do commit plagiarism, says a surgery retraction

The Importance of Being Reproducible: Keith Baggerly tells the Anil Potti story

For those Retraction Watch readers who have been following the case of Anil Potti — who has now retracted four papers — Keith Baggerly’s name will likely be familiar. Baggerly is the bioinformatician at M.D. Anderson in Houston who has been publicly questioning, in letters, papers, and The Cancer Letter, work by Potti et. al.

Yesterday, Baggerly gave a keynote at the Council of Science Editors meeting in Baltimore. It was a fascinating — and riveting — walk through how, after a group at M.D. Anderson asked him and his team to evaluate the Potti group’s tools for predicting whether given patients would respond to different chemotherapies, Baggerly’s group unraveled the Potti research.

In his talk, Baggerly demonstrated all of the mislabeling and other easily recognized errors his team found when they sifted through the raw data. And yet there were a number of wince-inducing moments in which Baggerly described the cool reception he had from several journals.

There have been a lot of calls recently that journals should require that authors deposit their data.  There’s none more powerful than when they come at the end of a talk showing how that could have stopped a faulty clinical trial from ever starting.

Baggerly told Retraction Watch he just wants this story to get the widest attention possible, so he was glad to allow us to post his slides. They get appropriately technical, given the crowd, but it’s worth it. You can follow a very unofficial and rough transcript at this Twitter search, since Ivan live-tweeted the talk. Or just click over to the slideshow here.

Roundup: A new record? And paper retracts story about Canadian Paxil researcher-turned pol Kutcher

We’ve both been at conferences — Adam at the Society of Cardiovascular Anesthesiologists in Savannah, and Ivan at the Council of Science Editors in Baltimore, where he’ll be on a panel today about finding fraud — so we haven’t had a lot of time to run down retractions. But there were a few retraction-related developments in the past few days that we wanted to highlight for Retraction Watch readers:

First, another great investigation by The Cancer Letter and The New York Times, this one into the International Early Lung Cancer Action Program (I-ELCAP) run by Claudia Henschke and David Yankelevitz. The design and conclusions of that trial has been criticized by other pulmonologists.

The new investigation, however, reveals that an October 2008 review of the study found that the researchers couldn’t find 90 percent of the subjects’ consent forms. That, The Cancer Letter notes, could mean a huge number of retractions that could displace Joachim Boldt as the current record holder: Continue reading Roundup: A new record? And paper retracts story about Canadian Paxil researcher-turned pol Kutcher

Feminism & Psychology study of UK birthing classes draws ire, winds up retracted

The debate — in entrenched medical circles, anyway — over whether it’s safe to give birth at home can be fierce. Just last month, for example, Nature reported that a review of the subject in the American Journal of Obstetrics & Gynecology that found home births more dangerous than those in the hospital generated so much controversy that it forced an investigation. Outside reviewers found problems, but the journal didn’t think they rose to the level of a retraction. Critics disagreed.

The same fraught subject came up in a paper published in Feminism & Psychology last year by Mary Horton-Salway and Abigail Locke. The original paper had concluded:

Our analysis suggests that the normativity of medical interventions in labour and childbirth is discursively reproduced in ante-natal classes whilst parental choice is limited by a powerful ‘rhetoric of risk’.

In other words, NCT classes were scaring women into choosing hospital births. But it turns out that conclusion wasn’t actually supported by the findings, which were based on a review of National Childbirth Trust’s classes. That led to a retraction: Continue reading Feminism & Psychology study of UK birthing classes draws ire, winds up retracted

Science publishes replication of Marc Hauser study, says results hold up

There has been some news over the past few weeks about Marc Hauser, the Harvard psychologist found guilty of misconduct by the university last year. First, because Harvard had listed him in a course catalog, The Crimson said that he might be teaching again, following a ban. But that turned out not to be the case, as The Boston Globe reported.

Today, Science lifted the embargo on a paper by Hauser and Justin Wood, now of the University of Southern California, showing that results published in the journal in 2007 — and later questioned — have held up. The abstract: Continue reading Science publishes replication of Marc Hauser study, says results hold up

Forget chocolate on Valentine’s Day, try semen, says Surgery News editor. Retraction, resignation follow

We have a bizarre tale to relate involving the journal Surgery News, which recently lost its editor-in-chief over a rather strange editorial he wrote in the February issue of the magazine.

The ill-fated — and, we’ll stipulate, ill-advised — commentary has led to a de facto retraction of the entire publication — meaning that although no retraction notice exists that we’re aware of, neither does the issue exist in the publication’s archives.

But first, some important background. Surgery News is a trade magazine with a complicated structure. The publication, which describes itself as “the official newspaper of the American College of Surgeons [ACS],” is published by Elsevier, which supplies medical news through its International Medical News Group division. The society provides its own news, as well as the lead editor, a surgeon, who until recently was Lazar Greenfield. Greenfield, of the University of Michigan, also happens to be the president-elect of the ACS, twin responsibilities that put him at the pinnacle of influence for his specialty.

Now back to the offending editorial, which we’ll bring you in its entirety since 1) we think given the events that you should read the whole thing, and 2) because the ACS has taken the entire February issue off its website we can’t link to it even if we wanted to (more on that later). Under the heading “Gut Feelings,” Greenfield wrote (we added links): Continue reading Forget chocolate on Valentine’s Day, try semen, says Surgery News editor. Retraction, resignation follow