Category: clinical study retractions

Society error leads to published — then retracted — Alzheimer’s abstract from top group

Alzheimer’s & Dementia has retracted a meeting abstract the journal published without the OK of the researchers, a top group from Harvard, who submitted it but withdrew the work before the conference.

That, as they say, might require some unpacking. Maybe this will make things clearer.

Raj Hooli, a graduate student in the lab of Rudolph Tanzi, a leading neuroscientist at Harvard — where he holds the Joseph P. and Rose F. Kennedy endowed chair of neurology — had submitted the abstract, “Genome-wide assessment of copy number variations in early-onset Alzheimer’s disease,” for consideration at the International Conference on Alzheimer’s Disease (ICAD).

As Tanzi explains: Continue reading Society error leads to published — then retracted — Alzheimer’s abstract from top group

Five papers by prominent cardiologist Hiroaki Matsubara subject to Expression of Concern

Hiroaki Matsubara

The American Heart Association, which publishes a number of journals, has issued an Expression of Concern about five papers in three of their publications, following allegations of image manipulation. All of the papers include Hiroaki Matsubara, of Kyoto Prefectural University, as a co-author.

The notice begins:

It has come to the attention of the American Heart Association (AHA), in a public manner, that there are questions concerning a number of figures in several AHA journals’ articles…

The “public manner” was three posts last year on the Abnormal Science blog, available here, here and here, alleging that images were manipulated in the manuscripts, and that histology slides were reused.

The notice continues: Continue reading Five papers by prominent cardiologist Hiroaki Matsubara subject to Expression of Concern

Update on Fujii: Anesthesia journal finds overwhelming statistical evidence of data fabrication

There’s a bit more this afternoon on the story of Yoshitaka Fujii, the Japanese anesthesiologist accused of fraud and other misconduct that we reported on yesterday.

The British journal Anaesthesia, which has been looking into Fujii’s research record, has posted four articles and editorials about the case and related issues on its website. One in particular is remarkable for its conclusions. Written by a UK anesthesiologist named John Carlisle, the article claims to have analyzed 169 randomized controlled trials that Fujii conducted between 1991 and 2011.

According to the abstract (which we formatted for readability, and which should be online shortly, we’re told): Continue reading Update on Fujii: Anesthesia journal finds overwhelming statistical evidence of data fabrication

Major fraud probe of Japanese anesthesiologist Yoshitaka Fujii may challenge retraction record

We have learned that a widely published Japanese anesthesiologist is under investigation by his university over concerns that he engaged in repeated fraud for decades that has tainted roughly 180 articles—many of which may be retracted as a result.

In a related move, the journal Clinical Therapeutics is retracting papers by the researcher, Yoshitaka Fujii, most recently of Toho University, in Tokyo. Judy Pachella, managing editor of the journal, confirmed the retractions but would not state how many papers were affected. Clinical Therapeutics published 17 articles by Fujii, between 2003 and 2010.

Continue reading Major fraud probe of Japanese anesthesiologist Yoshitaka Fujii may challenge retraction record

Another withdrawal by MD Anderson’s Aggarwal, again for unclear reasons

Bharat B. Aggarwal, the MD Anderson researcher under investigation at his institution over concerns of image manipulation, has withdrawn a second paper, although you’d never know why from the statement.

The notice for the article, “Evidence for the critical roles of NF-κB p65 and specificity proteins in the apoptosis-inducing activity of proteasome inhibitors in leukemia cells,” is pretty minimal: Continue reading Another withdrawal by MD Anderson’s Aggarwal, again for unclear reasons

Inquiry at Maimonides triggers two retractions in Chest, and retraining for the researchers

The journal Chest has retracted two publications — a paper and an earlier meeting abstract — from a group of researchers at Maimonides Medical Center in New York City after learning that the investigators mischaracterized the nature of their study. In addition to losing the two publications, the authors were ordered to undergo a refresher in proper research methods.

Here’s the notice for the abstract, which has been cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading Inquiry at Maimonides triggers two retractions in Chest, and retraining for the researchers

Tenth Potti retraction appears, in Clinical Cancer Research

Anil Potti and his colleagues have retracted another paper, “Characterizing the Clinical Relevance of an Embryonic Stem Cell Phenotype in Lung Adenocarcinoma,” originally published in the December 15, 2009, issue of Clinical Cancer Research.

According to the notice: Continue reading Tenth Potti retraction appears, in Clinical Cancer Research

Three AHA journals retract lipid papers over “negligent” record-keeping, image issues and more

Three journals belonging to the American Heart Association are dealing with a data manipulation case involving a Japanese scientist who collaborated with some of the United States’ most prominent  cardiac specialists.

Circulation has retracted a 2008 article after the researchers said the lead author’s sloppy record-keeping prevented them from reproducing their experiments. We think there might be a bit more to the story.

Here’s the notice: Continue reading Three AHA journals retract lipid papers over “negligent” record-keeping, image issues and more

Not so fast! Journal retracts paper from Boldt group over author hijinks, more

We knew we hadn’t heard the last of Joachim Boldt, whose nearly 90 retractions make him the putative record holder for a single author in this indistinguished club. But we didn’t expect this:

The European Journal of Anaesthesiology has retracted a paper, “Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting,” from Boldt’s former colleagues at the Klinikum Ludwigshafen after determining that the authors were trying to hide their association with the disgraced anesthesiologist.

Continue reading Not so fast! Journal retracts paper from Boldt group over author hijinks, more

Two mega-corrections for Anil Potti in the Journal of Clinical Oncology

Anil Potti can add two corrections to his less-and-less impressive publication record. The mega-corrections — part of what we are close to being ready to call a trend in errata notices — in the Journal of Clinical Oncology (JCO) are, however, quite impressive, each with at least a dozen points.

One of the corrections, for a paper cited 15 times, according to Thomson Scientific’s Web of Knowledge, basically removes all references to chemotherapy sensitivity: Continue reading Two mega-corrections for Anil Potti in the Journal of Clinical Oncology