Mystery box sinks immunology paper

Screen Shot 2014-06-30 at 12.30.32 PMBiochemical Journal has pulled a 2006 paper for an undisclosed “background subtraction box” in an image – which, if you take a not-particularly-close look at the figure to the right, means somebody added a black rectangle over the control lane.

Here’s the notice: for “Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity”: Continue reading Mystery box sinks immunology paper

Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

pnas 1113The Proceedings of the National Academy of Sciences (PNAS) is subjecting a much-criticized study involving Facebook that it published just two weeks ago to an Expression of Concern.

From the abstract of the original study: Continue reading Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

Author squabble sinks cardiology papers

Two papers on “novel techniques” have been retracted with what is unfortunately a very non-novel technique: an odd notice and silence when we asked for comment.

Here’s the explanation for retraction of “A novel approach to treat residual peridevice leakage after left-atrial appendage closure,” by Wunderlich N, Wilson N, and Sievert H: Continue reading Author squabble sinks cardiology papers

Bad spreadsheet merge kills depression paper, quick fix resurrects it

The authors of a paper showing a link between immune response and depression requested a retraction after they realized they’d merged two spreadsheets with mismatching ID codes.

Here’s the notice for “Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years,” retracted in February 2014:

Continue reading Bad spreadsheet merge kills depression paper, quick fix resurrects it

Wayward “contractor” prompts expression of concern for PLoS ONE paper on cancer cells

logoThe editors of PLoS ONE have issued an Expression of Concern (which seems likely to become a retraction) for a 2014 paper by a group of researchers in China who claim to have been led astray by a contractor hired to “edit the language” of the report.

The article, “Arsenic Sulfide Promotes Apoptosis in Retinoid Acid Resistant Human Acute Promyelocytic Leukemic NB4-R1 Cells through Downregulation of SET Protein,” came from a group in the Department of Hematology at the First Affiliated Hospital at Xi’an Jiaotong University, and was led by Yuwang Tian, a pathologist at the General Hospital of Beijing Military Area of PLA.

Or at least that’s what the manuscript eventually said. According to the expression of concern, however, that’s not what it said initially: Continue reading Wayward “contractor” prompts expression of concern for PLoS ONE paper on cancer cells

Alleged Medicare cheat loses paper for data mix-up

A Boston doctor indicted on charges of Medicare fraud in 2007 has had a paper relating to the case retracted this month.

Abdul Razzaque Ahmed was considered something of a miracle worker by his patients, treating two rare and disfiguring skin conditions called pemphigoid and pemphigus vulgaris. He used more powerful medicines than the typical course of treatment, including a drug normally used to treat cancer.

The initial indictment stated that Ahmed mixed blood samples to falsely show a “dual diagnosis” of both diseases, and prove to Medicare that they required the more rigorous (and expensive) treatment. It also alleged that he profited massively from the government pay-outs. He was convicted of obstruction in 2007; the other charges were dropped when he agreed to forfeit assets worth $2.9 million.

Now, a 2001 paper by Ahmed, which claimed fifteen patients had a dual diagnosis, has been retracted because the samples were all mixed. Here is the retraction notice from Clinical Immunology: Continue reading Alleged Medicare cheat loses paper for data mix-up

Cancer researcher facing criminal inquiry up to six retractions

jbc 620Alfredo Fusco, who is under criminal investigation in Italy for scientific fraud, has had two more papers retracted.

Both are in the Journal of Biological Chemistry (JBC). Here are the two studies: Continue reading Cancer researcher facing criminal inquiry up to six retractions

Cancer genetics group retracts three papers for “inappropriate presentation of data”

jbc 620A group of cancer genetics researchers in Italy and the U.S. has retracted three papers in the Journal of Biological Chemistry (JBC) after it became aware they had duplicated some bands in their figures.

Here are the three papers: Continue reading Cancer genetics group retracts three papers for “inappropriate presentation of data”

Unusual: HIV vaccine researcher who faked data arrested, faces felony charges

US Attorney Nicholas Klinefeldt

Dong Pyou-Han, a former researcher at Iowa State University who spiked rabbit blood samples to make it look as though a potential HIV vaccine was working, was arrested earlier this week on felony charges.

According to the Des Moines Register: Continue reading Unusual: HIV vaccine researcher who faked data arrested, faces felony charges

Duplication forces retraction of liver cancer paper

biomed research intBioMed Research International has retracted a 2013 paper after it became clear that it was lifted from another 2013 paper about the same subject by some of the same authors.

According to the retraction notice: Continue reading Duplication forces retraction of liver cancer paper