Caught Our Notice: Oops, wrong species

Title: Virulent Diuraphis noxia Aphids Over-Express Calcium Signaling Proteins to Overcome Defenses of Aphid-Resistant Wheat Plants

What Caught Our Attention: Sadly, it’s not uncommon for researchers to mistake the identity of what they’re working with — but not everyone comes clean and works to transparently correct the record. So it’s nice to see some authors among a group based in the US and India take the initiative to retract their paper after realizing they had based some of their conclusions on the wrong species of aphid. Continue reading Caught Our Notice: Oops, wrong species

Researcher at Japan stem cell institute falsified nearly all images in 2017 paper

Shinya Yamanaka

An investigation by Kyoto University in Japan has found a researcher guilty of falsifying all but one of the figures in a 2017 stem cell paper.

Yesterday, Kyoto University announced that the paper’s first author, Kohei Yamamizu, had fabricated and falsified data in the Stem Cell Reports paper. According to the investigation report, none of the other authors were involved in the data manipulation.

Yamamizu works at the Center for iPS cell Research and Application (CiRA) at Kyoto University, directed by Shinya Yamanaka, a Nobel Prize winner for his pioneering work in stem cell biology.

A spokesperson for the journal told us that the authors disclosed the problems last week and Stem Cell Reports will be retracting the paper, published last February.

In the university’s official statement, Yamanaka said: Continue reading Researcher at Japan stem cell institute falsified nearly all images in 2017 paper

“A painful lesson:” Authors retract paper after discovering mislabeled mouse lines

Neuroscientists have retracted a 2016 paper examining the genetic underpinnings of a degenerative motor neuron disease, after discovering that two mouse lines had been accidentally mislabeled.

According to the retraction notice, published in December in Acta Neuropathologica Communications, mice engineered to have a specific genetic mutation were mislabeled as the normal or wild type group.

The notice cites an investigation by the University of Florida; we asked the university for a copy of the report. The university sent us a redacted document, which a spokesperson told us was a self-report from the researchers regarding the mislabeling. The spokesperson explained: Continue reading “A painful lesson:” Authors retract paper after discovering mislabeled mouse lines

Caught Our Notice: Doesn’t anyone do a literature review any more?

Via Wikimedia

Titles: (1) Whole-Genome De Novo Sequencing of the Lignin-Degrading Wood Rot Fungus Phanerochaete chrysosporium (ATCC 20696)

(2) Structure revision of aspergicin by the crystal structure of aspergicine, a co-occurring isomer produced by co-culture of two mangrove epiphytic fungi

What Caught Our Attention: Two articles by different groups of authors recently suffered from the same (fatal) flaw: A poor literature review. The article, “Whole-Genome De Novo Sequencing of the Lignin-Degrading Wood Rot Fungus Phanerochaete chrysosporium (ATCC 20696),” claimed to have sequenced a strain already sequenced in 2004 and published in a well-cited article.  According to Clarivate Analytics’ Web of Science, the 2004 article was cited 474 times before the now-retracted article was published. And that 2004 article appeared in a highly-cited journal, Nature Biotechnology. Continue reading Caught Our Notice: Doesn’t anyone do a literature review any more?

Caught Our Notice: Journals still (slowly) purging archives of bad cell line studies

Via Wikimedia

Title: Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway

What Caught Our Attention: Thousands of papers have relied on contaminated or wrong cell lines, a problem journals have not been particularly proactive in addressing. So far, only a few studies have been retracted for using misidentified cell lines. Continue reading Caught Our Notice: Journals still (slowly) purging archives of bad cell line studies

Journal retracts “hopelessly flawed” paper linking cell phone radiation to pain

Mario Romero-Ortega. Credit: UT-Dallas

A journal is retracting a paper linking radio waves from cell phone towers to pain in amputees, despite objections from the authors.

Anthropogenic Radio-Frequency Electromagnetic Fields Elicit Neuropathic Pain in an Amputation Model,” originally published Jan. 16, 2016 in PLOS ONE, suggested that rats with injured nerves experienced pain when exposed to the type of electromagnetic radiation emitted by cell phone network towers. A press release issued by the University of Texas at Dallas (UT-Dallas) — where the corresponding author Mario Romero-Ortega and two co-first authors are based — said that this phenomenon has been reported anecdotally by people missing limbs.

But the study, especially its methodology, met with immediate criticism in the article’s comment section. PLOS ONE noted in March 2016 that the authors had contacted the journal regarding an error in some of the exposure levels reported in the study, which journal staff were “looking into.” In December 2016, the journal told the authors it was going to retract the paper. Now, more than one year later, it finally has.

Ken Foster, a professor at the University of Pennsylvania who commented in February 2016 that the paper was “hopelessly flawed,” told us: Continue reading Journal retracts “hopelessly flawed” paper linking cell phone radiation to pain

Caught Our Notice: Unusual — journal flags paper for concerns, then updates them

Via Wikimedia

Title: Filled and peptide-modified single-walled carbon nanotubes: synthesis, characterization, and in vitro test for cancer cell targeting

What Caught Our Attention: After an expression of concern (EOC) is published in a journal, the usual procedure is to either publish a subsequent correction or retraction — or, unfortunately, leave it sit ad infinitum. But apparently, there’s another option. Continue reading Caught Our Notice: Unusual — journal flags paper for concerns, then updates them

Caught Our Notice: After ORI flags a paper by former grad student, university flags another

Via Wikimedia

Title: The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer

What Caught Our Attention: Six months ago, the U.S. Office of Research Integrity (ORI) determined that former graduate student Brandi Baughman had doctored 11 figures in a PLOS ONE article, which was retracted shortly after.  The PLOS ONE paper listed two affiliations for Baughman — the National Institute of Environmental Health Sciences and the University of North Carolina, Chapel Hill (UNC); now UNC has triggered a second retraction of a paper co-authored by Baughman, also due to research misconduct. Although the ORI notice makes no mention of this additional paper, the agency recently took a “targeted approach” by not issuing comprehensive findings of misconduct for one researcher, in order to conserve resources. Of course, sometimes universities make findings that don’t meet the ORI’s bar, too. Continue reading Caught Our Notice: After ORI flags a paper by former grad student, university flags another

Caught Our Notice: Researcher who sued PubPeer commenter draws 19th retraction  

Via Wikimedia

Title: Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells

What Caught Our Attention: We’ve been following cancer scientist Fazlul Sarkar for years, as he (unsuccessfully) sought to expose the identity of a PubPeer commenter who he believes cost him a job offer. In November 2016, the ACLU released a copy of a misconduct investigation report compiled by Wayne State University, which concluded Sarkar ran a laboratory “culture” of “fabrication, falsification and/or plagiarism of data,” and recommended the retraction of 42 papers and correction of 10 papers. He’s now lodged his 19th retraction. Continue reading Caught Our Notice: Researcher who sued PubPeer commenter draws 19th retraction  

Paper retracted when co-author forgets he had published a figure before

A 2016 case study in Neurology exploring a “mystery case” has been retracted because four figures had already been published in a 2012 article.

The two papers have three authors in common, but according to the retraction notice, none could explain the duplicate publication. The notice states that Pierre Labauge, the corresponding author on the 2012 paper and the last author on the Neurology paper, said he “did not remember the first paper” when revising the recent one. Continue reading Paper retracted when co-author forgets he had published a figure before