Category: basic life sciences retractions

Data highjinx forces retraction of tumor paper in JBC

jbccover414The Journal of Biological Chemistry has an illuminating retraction notice — we’re happy to be able to say — about a 2001 article from a group of researchers at the National University of Singapore.

The paper, “Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells,” was written by Jayshree L. Hirpara, Marie-Véronique Clément and Shazib Pervaiz.

It has has been cited 110 times, according to Thomson Scientific’s Web of Knowledge. According to the retraction notice: Continue reading Data highjinx forces retraction of tumor paper in JBC

NIH/Harvard team loses aging study to manipulated data

agecoverAge has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.

The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.

As the abstract explained: Continue reading NIH/Harvard team loses aging study to manipulated data

Anonymous blog comment suggests lack of confidentiality in peer review — and plays role in a new paper

neuronA new paper in Intelligence is offering some, well, intel into the peer review process at one prestigious neuroscience journal.

The new paper is about another paper, a December 2012 study, “Fractionating Human Intelligence,” published in Neuron by Adam Hampshire and colleagues in December 2012. The Neuron study has been cited 16 times, according to Thomson Scientific’s Web of Knowledge.

Richard Haier and colleagues write in Intelligence that Continue reading Anonymous blog comment suggests lack of confidentiality in peer review — and plays role in a new paper

Nature corrects a correction

nature 4 9 14Last year, we reported on a Nature correction of a paper for what a McGill University committee had earlier called “intentionally contrived and falsified” figures. It turns out that the correction — like the original paper — left some Nature readers puzzled, so the journal has run a correction of the correction: Continue reading Nature corrects a correction

Fraud fells Alzheimer’s “made to order” neurons paper in Cell

cell414In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

Continue reading Fraud fells Alzheimer’s “made to order” neurons paper in Cell

Lack of citation prompts correction in Nature journal

nature communicationsIt’s not unusual to hear authors bemoan the fact that a new paper doesn’t cite their work that set the stage for a scientific advance. “The journal limited me to [a seemingly abitrary number of] references,” authors sometimes shrug, with or without apology. This week, however, we found a case of that which seems to have been resolved to everyone’s satisfaction.

The authors of a September 2013 article in Nature Communications have issued a correction for the piece, which failed to cite the source of a key step in their experiment.

The article, “Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction,” came from the lab of William “Clay” Bracken, a biochemist at Weill Cornell Medical College. According to the abstract: Continue reading Lack of citation prompts correction in Nature journal

Waseda University checking dissertations for plagiarism in wake of STAP stem cell misconduct finding

wasedaWaseda University in Japan says it will be vetting every doctoral dissertation it awards its graduate-level students in Advanced Science & Engineering* for signs of plagiarism, according to a report in the Japan News, a site of the Yomiuri Shimbun. The paper reports that:

Continue reading Waseda University checking dissertations for plagiarism in wake of STAP stem cell misconduct finding

Pain study retracted for bogus data is second withdrawal for University of Calgary group

molpainBack in January 2013, we wrote about the retraction of a paper in Diabetes that the authors had “submitted without knowledge of inherent errors or abnormalities that they recognized in retrospect after submission.”

Now, Molecular Pain has retracted a paper by the same authors, this time for data manipulation. The article, “Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states,” was written by Cory Toth, a clinical neuroscientist at the University of Calgary, in Canada, and colleagues. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

Toth said of the Diabetes article at the time:
Continue reading Pain study retracted for bogus data is second withdrawal for University of Calgary group

Regenerative medicine, regenerative publishing

devbioDevelopmental Biology has retracted a 2009 paper by an group of regenerative medicine specialists who, it seems, were regenerating more than just cells.

The article, titled “The human placenta is a hematopoietic organ during the embryonic and fetal periods of development,” was led by Susan Fisher, of the Institute for Regenerative Medicine at the University of California, San Francisco. It has been cited 32 times, according to Thomson Scientific’s Web of Knowledge.

According to the abstract: Continue reading Regenerative medicine, regenerative publishing

“I am deeply saddened and disturbed:” Co-author of retracted Nature paper reveals how problems came to light

Ben Scheres
Ben Scheres

On Wednesday, we reported on a Nature retraction of a paper whose corresponding author had also had a Cell paper retracted, and had been found to have committed a “violation of academic integrity” by Utrecht University. Today, we present the back story of how those retractions came to be, from another co-author of both papers, Ben Scheres, of Wageningen University: Continue reading “I am deeply saddened and disturbed:” Co-author of retracted Nature paper reveals how problems came to light