Category: basic life sciences retractions

Swiss, French institutions investigating several papers

eth-zurichcnrsInstitutions in France and Switzerland are investigating figures in several molecular biology papers, according to a joint press release published today.

Unfortunately, there’s not much more we can tell you about the investigation — the press release doesn’t specify the names of researchers, journals, or even the area within molecular biology that’s under scrutiny.

The National Center for Scientific Research (CNRS) in France will lead the inquiry, with contribution from ETH Zürich in Switzerland. Molecular biology researchers from both institutions were involved in the flagged publications, an ETH Zürich spokesperson told us.

The ETH Zürich spokesperson added: Continue reading Swiss, French institutions investigating several papers

Authors didn’t generate key brain images, probe finds

Frontiers in Human NeuroscienceA neuroscience journal has issued a retraction after discovering some of the paper’s integral images didn’t originate from the authors’ labs.

The retraction notice  — for a study about a condition once known as “water on the brain” — cites an investigation by the journal’s publisher, Frontiers, which determined that the figures were not “duly attributed.” The authors say they agree with the retraction.  

Here’s the retraction notice for “Revisiting hydrocephalus as a model to study brain resilience,” published by Frontiers in Human Neuroscience: Continue reading Authors didn’t generate key brain images, probe finds

Biologist loses second paper — again, for unvalidated figures

Cellular SignallingA researcher at Case Western Reserve University in Ohio has retracted a second paper after a review found the figures didn’t match the original data.  

Last year, we reported on a previous retraction of a paper co-authored by biologist Alan Levine in Inflammatory Bowel Diseases, which was pulled for the exact same reason; even the retraction notices use similar language. The first author on both papers is Debasmita Mandal, also listed at Case Western Reserve University.

Here’s the retraction notice for “REDOX regulation of IL-13 signaling in intestinal epithelial cells: usage of alternate pathways mediates distinct gene expression patterns,” published by Cellular Signalling: Continue reading Biologist loses second paper — again, for unvalidated figures

Despite apology, bagpipes study not slated for retraction

Thorax

It’s not often that a paper elicits an apology — but that’s just what happened when family members first learned a bagpipe musician died from inhaling mold and fungi from a case study reported in a journal. The hospital has since apologized; the journal, however, told us it is not planning to issue a retraction.

The University Hospital of South Manchester NHS Foundation Trust in Wythenshawe, UK, has apologized and launched an internal investigation into the case report after the family’s distress was extensively covered by the UK’s mainstream media, such as The BBC, The Independent, The Daily Mail, and The Telegraph.

There seem to be conflicting accounts over whether any consent was obtained to publish the report. The Thorax paper says the patient gave consent, and according to Gisli Jenkins, co-editor-in-chief of the journal and a professor of experimental medicine at Nottingham University in the UK, consent was sought from the family. But the patient’s daughter told us that neither the next of kin nor the patient were approached for consent. 

The release of the report on August 22 was “completely unethical,” said Erin Tabinor, daughter of musician Bruce Campbell and a makeup artist in Liverpool, UK. Tabinor told us that the family wasn’t aware that playing bagpipes was the cause of Campbell’s death: Continue reading Despite apology, bagpipes study not slated for retraction

Cancer researcher logs 5th retraction

Journal of Mammary Gland Biology and NeoplasiaA cancer researcher has added a fifth retraction to his name — but the notice doesn’t mention any problems with the paper itself. 

Rather, the Journal of Mammary Gland Biology and Neoplasia decided to retract the paper because it referenced other papers that had been retracted as a result of data manipulation.

The notice doesn’t specify which references were problematic, but the list includes three papers that are now retracted; all three include Scott Valastyan (the sole author of the newly retracted paper) as first author, and two list Robert Weinberg, his former supervisor and prominent cancer researcher, as last author.

Continue reading Cancer researcher logs 5th retraction

Retraction appears for group whose former member was sanctioned by ORI

Journal of Biological ChemistryResearchers whose former colleague was recently reprimanded by the U.S. Office of Research Integrity (ORI) have retracted a biology paper for duplication.

The retraction includes some familiar names: The last author Steven Grant, senior author of the newly retracted study, is also the last author of 11 papers flagged in a report by the ORI in December, 2015. That report focused on Girija Dasmahapatra, a co-author of the 11 studies who was also based at at Virginia Commonwealth University (VCU). Dasmahapatra left VCU in 2015, and is not listed on the latest retraction.

The retracted paper, published in The Journal of Biological Chemistry (JBC), was also co-authored by Paul Dent, a biochemist at the VCU, who we mentioned last year when he offered to retract another paper in Molecular Pharmacology after concerns arose on PubPeer. The journal has instead issued a lengthy correction (what we call a “mega-correction”).

A VCU spokesperson told us:
Continue reading Retraction appears for group whose former member was sanctioned by ORI

Widely used brain tumor cell line may not be what researchers thought it was

Bengt Westermark
Bengt Westermark

Nearly 50 years ago, researchers in Uppsala, Sweden used cells from a patient to establish a brain tumor cell line that has become widely used. But a new study suggests that the most common source of that cell line used by scientists today may not be derived from that original patient’s tumor, raising questions about the results obtained in hundreds of studies.

In a new paper out today in Science Translational Medicine, Bengt Westermark, of Uppsala University, and colleagues describe what they found when they performed a forensic DNA analysis comparing the widely used version of the cell line to the original. The findings are consistent with those of other analyses in which cell lines turn out not to be what researchers thought, a problem we’ve focused some attention on.

Here’s an email interview with Westermark about the findings and their implications: Continue reading Widely used brain tumor cell line may not be what researchers thought it was

Former NIH postdoc doctored data

ori-logoA genetics researcher included falsified data in two published papers, according to a report by the U.S. Office of Research Integrity (ORI) released today.

At the time of the misconduct, Andrew Cullinane was a postdoctoral fellow in the Medical Genetics Branch at the National Human Genome Research Institute (NHGRI). According to his LinkedIn page, he is now an assistant professor at Howard University in Washington D.C. The university’s College of Medicine lists him as an assistant professor in the Basic Sciences/Anatomy department.

As today’s notice in the Federal Register reports, Cullinane Continue reading Former NIH postdoc doctored data

Former professor shoots dean who fired him for misconduct

MountSinai_IcahnSchool_LogoA former assistant professor at the Mount Sinai School of Medicine in New York fired a shotgun yesterday at two men– including the school’s dean, who had fired him six years ago.

The New York Times reports that Hengjun Chao was taken into custody on charges of attempted murder, after his shots hit Mount Sinai dean Dennis Charney and another man outside of a suburban New York deli. Both men were treated at a local hospital for non-life-threatening injuries.

Chao was fired from Mount Sinai in 2010 after an investigating committee found that he Continue reading Former professor shoots dean who fired him for misconduct

Scotland researcher suspended during misconduct probe: report

Robert Ryan
Robert Ryan

A prominent researcher in Scotland has been suspended amidst a misconduct investigation at the University of Dundee.

According to The Scotsman, the allegations against Robert Ryan center around falsifying data and duplicating figures in his work about molecular bacteriology.

As the outlet reports: Continue reading Scotland researcher suspended during misconduct probe: report