Category: basic life sciences retractions

Despite apology, bagpipes study not slated for retraction

Thorax

It’s not often that a paper elicits an apology — but that’s just what happened when family members first learned a bagpipe musician died from inhaling mold and fungi from a case study reported in a journal. The hospital has since apologized; the journal, however, told us it is not planning to issue a retraction.

The University Hospital of South Manchester NHS Foundation Trust in Wythenshawe, UK, has apologized and launched an internal investigation into the case report after the family’s distress was extensively covered by the UK’s mainstream media, such as The BBC, The Independent, The Daily Mail, and The Telegraph.

There seem to be conflicting accounts over whether any consent was obtained to publish the report. The Thorax paper says the patient gave consent, and according to Gisli Jenkins, co-editor-in-chief of the journal and a professor of experimental medicine at Nottingham University in the UK, consent was sought from the family. But the patient’s daughter told us that neither the next of kin nor the patient were approached for consent. 

The release of the report on August 22 was “completely unethical,” said Erin Tabinor, daughter of musician Bruce Campbell and a makeup artist in Liverpool, UK. Tabinor told us that the family wasn’t aware that playing bagpipes was the cause of Campbell’s death: Continue reading Despite apology, bagpipes study not slated for retraction

Cancer researcher logs 5th retraction

Journal of Mammary Gland Biology and NeoplasiaA cancer researcher has added a fifth retraction to his name — but the notice doesn’t mention any problems with the paper itself. 

Rather, the Journal of Mammary Gland Biology and Neoplasia decided to retract the paper because it referenced other papers that had been retracted as a result of data manipulation.

The notice doesn’t specify which references were problematic, but the list includes three papers that are now retracted; all three include Scott Valastyan (the sole author of the newly retracted paper) as first author, and two list Robert Weinberg, his former supervisor and prominent cancer researcher, as last author.

Continue reading Cancer researcher logs 5th retraction

Retraction appears for group whose former member was sanctioned by ORI

Journal of Biological ChemistryResearchers whose former colleague was recently reprimanded by the U.S. Office of Research Integrity (ORI) have retracted a biology paper for duplication.

The retraction includes some familiar names: The last author Steven Grant, senior author of the newly retracted study, is also the last author of 11 papers flagged in a report by the ORI in December, 2015. That report focused on Girija Dasmahapatra, a co-author of the 11 studies who was also based at at Virginia Commonwealth University (VCU). Dasmahapatra left VCU in 2015, and is not listed on the latest retraction.

The retracted paper, published in The Journal of Biological Chemistry (JBC), was also co-authored by Paul Dent, a biochemist at the VCU, who we mentioned last year when he offered to retract another paper in Molecular Pharmacology after concerns arose on PubPeer. The journal has instead issued a lengthy correction (what we call a “mega-correction”).

A VCU spokesperson told us:
Continue reading Retraction appears for group whose former member was sanctioned by ORI

Widely used brain tumor cell line may not be what researchers thought it was

Bengt Westermark
Bengt Westermark

Nearly 50 years ago, researchers in Uppsala, Sweden used cells from a patient to establish a brain tumor cell line that has become widely used. But a new study suggests that the most common source of that cell line used by scientists today may not be derived from that original patient’s tumor, raising questions about the results obtained in hundreds of studies.

In a new paper out today in Science Translational Medicine, Bengt Westermark, of Uppsala University, and colleagues describe what they found when they performed a forensic DNA analysis comparing the widely used version of the cell line to the original. The findings are consistent with those of other analyses in which cell lines turn out not to be what researchers thought, a problem we’ve focused some attention on.

Here’s an email interview with Westermark about the findings and their implications: Continue reading Widely used brain tumor cell line may not be what researchers thought it was

Former NIH postdoc doctored data

ori-logoA genetics researcher included falsified data in two published papers, according to a report by the U.S. Office of Research Integrity (ORI) released today.

At the time of the misconduct, Andrew Cullinane was a postdoctoral fellow in the Medical Genetics Branch at the National Human Genome Research Institute (NHGRI). According to his LinkedIn page, he is now an assistant professor at Howard University in Washington D.C. The university’s College of Medicine lists him as an assistant professor in the Basic Sciences/Anatomy department.

As today’s notice in the Federal Register reports, Cullinane Continue reading Former NIH postdoc doctored data

Former professor shoots dean who fired him for misconduct

MountSinai_IcahnSchool_LogoA former assistant professor at the Mount Sinai School of Medicine in New York fired a shotgun yesterday at two men– including the school’s dean, who had fired him six years ago.

The New York Times reports that Hengjun Chao was taken into custody on charges of attempted murder, after his shots hit Mount Sinai dean Dennis Charney and another man outside of a suburban New York deli. Both men were treated at a local hospital for non-life-threatening injuries.

Chao was fired from Mount Sinai in 2010 after an investigating committee found that he Continue reading Former professor shoots dean who fired him for misconduct

Scotland researcher suspended during misconduct probe: report

Robert Ryan
Robert Ryan

A prominent researcher in Scotland has been suspended amidst a misconduct investigation at the University of Dundee.

According to The Scotsman, the allegations against Robert Ryan center around falsifying data and duplicating figures in his work about molecular bacteriology.

As the outlet reports: Continue reading Scotland researcher suspended during misconduct probe: report

U Colorado’s former “golden boy” up to 7 retractions

University of Colorado DenverA former graduate student at the University of Colorado Denver has gained three retractions and two expressions of concern (EOC), following an institutional probe into his work. 

Last year, we reported on an investigation by the University of Colorado Denver into the research of Rajendra Kadam, which recommended retracting 10 papers. The report also flagged eight additional papers co-authored by Kadam whose data could not be validated, raising “concerns as to the scientific validity and integrity” of the material. A few months later, we reported on some of the notices — four retractions and an EOC — that had begun to appear for Kadam’s manuscripts.

We’ve since discovered more notices, bringing his total to seven retractions and three EOCs. 

Kadam was once a prominent member in the lab of Uday Kompella, and often referred to by colleagues as the “golden boy,” according to the institution’s report. In 2012, he won a graduate student symposium award from the American Association of Pharmaceutical Scientists.

A University of Colorado Denver spokesperson told Retraction Watch: Continue reading U Colorado’s former “golden boy” up to 7 retractions

7th retraction for Ohio researcher who manipulated dozens of figures

Terry Elton, via OSU
Terry Elton

A pharmacology researcher at Ohio State University has added his seventh retraction, four years after a finding of misconduct by the U.S. Office of Integrity (ORI).

An analysis of the work of Terry Elton determined that he had

falsified and/or fabricated Western blots in eighteen (18) figures and in six (6) published papers.

 In 2012, the ORI finding, which resulted in a three-year funding ban (that is now complete), recommended that Elton retract all six papers, one of which had already been retracted at the time of the report. 

Four years later, the last of the six papers flagged by the ORI has finally been retracted by Molecular and Cellular Endocrinology.

Here’s the retraction notice: Continue reading 7th retraction for Ohio researcher who manipulated dozens of figures

A retraction cluster? Two papers retracted for overlap with other retractions

molecular biology reportA cluster of papers by different authors has been retracted for sharing text, even though some papers were submitted at the same time.

How is that possible? A spokesperson for Springer told us that they have reason to believe a third-party company may have helped prepare the papers for publication, and in the process might have spread the material around to multiple manuscripts.

The details of the cluster are a bit perplexing, so bear with us. Two of the papers — that were published only months apart — have already been retracted, as we reported in April. Now, two other papers have been retracted from Molecular Biology Reports — and both notices cite the previously retracted papers. The new notices also say that there’s reason to believe that the peer-review process was compromised.

All papers conclude that a certain polymorphism could signal a risk for coronary artery disease among Chinese people.

We’ll start with the retraction notice for “Fibroblast growth factor receptor 4 polymorphisms and coronary artery disease: a case control study,” which cites the two papers that were retracted previously:

Continue reading A retraction cluster? Two papers retracted for overlap with other retractions