Columbia University misconduct retraction highlights what’s wrong with the retraction process

jcacoverThe Journal of Clinical Anesthesia has a retraction of a 2006 paper by a group from Columbia University that, to our minds, is the poster child for how not to handle such things.

The article, “Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery,” was written by Robert J. Frumento, Helene G. Logginidou, Staffan Wahlander, Gebhard Wagener, Hugh R. Playford and Robert N. Sladen, who now is chief of critical care at the institution. The paper has been cited 30 times, according to Thomson Scientific’s Web of Knowledge.

Why do we bother to name all the authors? Here’s why: According to the retraction notice, one of them — but don’t ask which — is guilty of research misconduct: Continue reading Columbia University misconduct retraction highlights what’s wrong with the retraction process

Lancet retracts Jikei Heart Study of valsartan following investigation

logo_lancetThe Lancet has retracted a study of Novartis’ blood pressure drug valsartan (Diovan) that has been subject to an investigation following the retraction of a related study earlier this year.

Continue reading Lancet retracts Jikei Heart Study of valsartan following investigation

Regrettable, but not scientifically dishonest: Klarlund Pedersen responds to Danish committee

Klarlund Pedersen
Klarlund Pedersen

A Danish researcher has responded to a draft report of the Danish Committees on Scientific Dishonesty (DCSD) that found she had acted in a “scientifically dishonest” and “grossly negligent” manner.

Bente Klarlund Pedersen, a University of Copenhagen researcher, has published with Milena Penkowa, four of whose papers have been retracted following investigations. In the press, she argued that while she had made mistakes, she had not committed misconduct.

The 57-page letter from Klarlund Pedersen’s attorney to the DCSD responds in detail to the critique of her work, including twelve papers. This passage from the summary gathers the arguments together: Continue reading Regrettable, but not scientifically dishonest: Klarlund Pedersen responds to Danish committee

Aussie university halts trials of skin cancer drug whose developer has four retractions

khachigian
Khachigian

An Australian university has put a hold on trials of an experimental drug for skin cancer whose main developer has been dogged by charges of research misconduct for several years.

The Australian Broadcasting Corporation is reporting that the University of New South Wales has suspended trials of the drug, DZ13, while it investigates the work of Levon Khachigian, who is leading the studies.

According to the news organization, Khachigian and his group were cleared by the school in two prior inquiries. However, additional accusations of misconduct — specifically involving image manipulation and misuse — prompted a third investigation.

We’ve found four retractions of Khachigian’s studies, from the Journal of Biological Chemistry and Biochemical and Biophysical Research Communications, between 2009 and 2010 (before the launch of Retraction Watch).

They are: Continue reading Aussie university halts trials of skin cancer drug whose developer has four retractions

Penkowa notches fourth retraction, in Experimental Neurology

exp neuroMilena Penkowa, the Danish neuroscientist who resigned from the University of Copenhagen in December 2010 amid suspicions of misconduct, has had another paper retracted.

The new retraction appears in Experimental Neurology. Here’s the notice for “M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6-aminonicotinamide treatment”: Continue reading Penkowa notches fourth retraction, in Experimental Neurology

University of Utah finds former faculty member guilty of misconduct because of “reckless disregard”

utahSince last May, we’ve been reporting on a case at the University of Utah involving two retractions and two corrections. When the story first broke, the lab blamed a former worker for inappropriately removing data from the premises, and the university has been investigating. Last month, we reported that Ivana De Domenico, the junior faculty member who was first author on those papers, had left the university, and that senior author Jerry Kaplan had retired.

But the problems went beyond the four papers we reported on, as the Salt Lake Tribune reported on Friday. In a 9-page report provided to the Tribune, the panel overseeing the investigation details its examination of 11 papers. This is the first of six findings: Continue reading University of Utah finds former faculty member guilty of misconduct because of “reckless disregard”

University, funding agency clear researcher Rui Curi of fraud charges

Rui Curi
Rui Curi

The University of São Paulo and Brazil’s National Council of Technological and Scientific Development funding agency (CNPq) have cleared a researcher of fraud following a six-month investigation.

The CNPq’s Commission on Integrity in Scientific Activity noted, however, that “there was failure to exercise rigor in the conduct and dissemination of results [in Rui Curi’s work], essential to quality research.” Continue reading University, funding agency clear researcher Rui Curi of fraud charges

Imperial clears Jatinder Ahluwalia of misconduct, blames “protracted negotiation” with Novartis for delay

logo_imperial_college_londonImperial College London has found that a former graduate student there — who had been found guilty of misconduct in two other institutions — did not commit fraud while at Imperial.

As first reported in the Times Higher Education today: Continue reading Imperial clears Jatinder Ahluwalia of misconduct, blames “protracted negotiation” with Novartis for delay

Three retractions, two lawsuits, one institutional inquiry for San Diego orthopedic surgeon

11832_5_2_OC.inddThree retractions, two lawsuits, one institutional inquiry. That’s not the kind of math anyone likes to do — but it’s the tally for Harish Hosalkar, a San Diego surgeon specializing in pediatric orthopedics.

Hosalkar became embroiled in a messy affair after problems surfaced in data he had published while at Rady Children’s Hospital — a facility he left under a cloud of recriminations. More on that in a bit. Continue reading Three retractions, two lawsuits, one institutional inquiry for San Diego orthopedic surgeon

Retraction of 19-year-old Nature paper reveals hidden cameras, lab break-in, evidence tampering

nature bezouskaWe’ve often found that when some authors refuse to sign retraction notices, there’s a much bigger story than terse notices let on. And a retraction in this week’s Nature of a 19-year-old paper is a shining example of that.

Here’s the brief notice for “Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity,” a 1994 paper by researchers from the UK and the Czech Republic that had already been subject to a 1996 correction: Continue reading Retraction of 19-year-old Nature paper reveals hidden cameras, lab break-in, evidence tampering