Category: image manipulation

Another “first author has accepted responsibility” retraction from immunity journal

IAIScientists have pulled their 2013 Infection and Immunity paper after a reader noticed duplicated data in three figures, and the first author was “unable to provide the original data used to construct the figures,” according to the journal’s editor-in-chief.

According to the retraction note, “the first author has accepted responsibility for these anomalies” — similar to another recent retraction from the same journal, also due to image duplication reported by a reader (apparently the journal has one or more careful readers).

The paper, “Pseudomonas aeruginosa Outer Membrane Vesicles Modulate Host Immune Responses by Targeting the Toll-Like Receptor 4 Signaling Pathway,” concerns the role of outer membrane vesicles excreted by the bacteria to incite an inflammatory response in mice. It was written by authors at the University of North Dakota, Sichuan University in China, and the University of Chicago, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

Here’s the complete retraction note:

Continue reading Another “first author has accepted responsibility” retraction from immunity journal

“A decision of misconduct was reached”: Two lung papers expire

JofAnesthTwo papers about the molecular underpinnings of lung damage are being retracted following an investigation at Oita University in Japan, which revealed that images from both papers had been used to depict “different experimental conditions” in a third paper (which has not been retracted).

It’s not clear which of the authors were the subject of the investigation. The two retracted papers, “Nafamostat mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury” in the Journal of Anesthesia and “Coexpression of HSP47 Gene and Type I and Type III Collagen Genes in LPS-Induced Pulmonary Fibrosis in Rats” in Lung, both originally published in 2007, share the same first author — Satoshi Hagiwara, whose affiliation is listed as the Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine. The papers have been cited 13 times and 12 times, respectively, according to Thomson Scientific’s Web of Knowledge. Hagiwara is also the first author on the third paper that contains the duplicated images.

The first retraction notice reads:

Continue reading “A decision of misconduct was reached”: Two lung papers expire

Cell Press investigating possible image manipulation in influential yeast genetics paper

cellCell Press is looking into anonymous allegations that a pair of influential papers on gene activation in yeast may contain more than two dozen instances of image manipulation, according to a spokesperson for the journal.

The accusations first appeared in March on PubPeer, where they triggered a small avalanche of comments, including one asserting “unambiguous and repeated examples of data re-use.”

The concerns raised on PubPeer have even sparked an investigation by an institution in Spain, which found no evidence to support the allegations. But not everyone agrees with that verdict.

Continue reading Cell Press investigating possible image manipulation in influential yeast genetics paper

Heart repair study retraction marks second for Mercer University researcher

BasicResCardio_ak12Authors of a study on cardiac repair after heart attack are retracting it from Basic Research in Cardiology because they used “the same samples… to represent two distinct groups on two occasions.”

We find the language of the retraction somewhat confusing, but to the best of our understanding it means that they compared apples to the exact same apples.

The study, published online in 2012, examined the mechanism behind the beneficial effects of a procedure called postconditioning in treating heart attacks. Here’s the retraction notice: Continue reading Heart repair study retraction marks second for Mercer University researcher

“The first author assumes all responsibility:” Malaria vaccine article retracted for image manipulation

InfectAndImmunAuthors of a 2012 article in Infection and Immunity investigating a malaria vaccine strategy are retracting it because it “contains several images that do not accurately reflect the experimental data.”

The paper, “Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes,” has been cited 9 times, according to Thomson Scientific’s Web of Knowledge.

The retraction notice places the blame for the image shenanigans squarely on the first author, Asim Siddiqui, who is currently listed on LinkedIn as a faculty member at the College of Applied Medicine at King Saud University in Saudi Arabia.

Here’s the notice: Continue reading “The first author assumes all responsibility:” Malaria vaccine article retracted for image manipulation

ORI-sanctioned former UT-Southwestern cancer researchers up to 10 retractions

CLThere’s been a 10th retraction from two former postdocs at a UT-Southwestern cancer research center who were sanctioned by the Office of Research Integrity (ORI) last September, in part due to observations and comments from Retraction Watch readers.

It’s a 2008 Cancer Letters paper, “Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer,” retracted at the request of Makoto Suzuki, the first author who has claimed responsibility for falsifying data in this and five other papers. Continue reading ORI-sanctioned former UT-Southwestern cancer researchers up to 10 retractions

“[W]e can learn from these bad actors:” Trail of retractions follows former Vanderbilt researcher’s fraud

JPhysiol_ak15Authors have retracted three papers from the Journal of Physiology because they contained “falsified or fabricated data.”

The papers, which address calcium signaling in heart muscle cells, are among the six pegged for retraction after an Office of Research Integrity (ORI) investigation into one of the authors, Igor Dzhura, formerly of Vanderbilt University. The ORI found that Dzhura had committed an enormous amount of fraud, involving dozens of faked images and more.

Dzhura was fired from a job at Novartis in November after the company discovered that his application had included the fraudulent work.

The three retracted Journal of Physiology papers and their citation figures, courtesy of Thomson Scientific’s Web of Knowledge, are: Continue reading “[W]e can learn from these bad actors:” Trail of retractions follows former Vanderbilt researcher’s fraud

Third retraction for GWU biologist as university seeks to dismiss his $8 million lawsuit

Rakesh Kumar, via George Washington University
Rakesh Kumar, via George Washington University

Cancer biologist Rakesh Kumar has chalked up another retraction, this time for “identical,” “duplicated,” and “replicated” figures and images.

It comes on the heels of a flurry of motions in Kumar’s $8 million lawsuit against his employer, George Washington University, for breach of contract and emotional distress because it removed him as department chair last year and placed his research on hold. Kumar remains employed by the university.

The retracted paper, published in Development in 2004, “Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis,” analyzed the role of a protein, MTA1, in mammary gland development and cancer. It was published while Kumar was at M.D. Anderson in Houston, and has been cited 81 times, according to Thomson Scientific’s Web of Knowledge.

By our count, Kumar now has three retractions and five corrections. Numerous anonymous comments on Kumar’s papers have been posted on PubPeer, many of them critiquing images. Here’s the complete notice from Development: Continue reading Third retraction for GWU biologist as university seeks to dismiss his $8 million lawsuit

NIH cancer paper retracted for faked data

JCIFollowing an investigation into research misconduct, the Journal of Clinical Investigation has retracted a cancer genetics paper from a laboratory at the National Institutes of Health due to “data falsification and fabrication” of four figures and a table in the paper.

The paper, “FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer,” describes an overexpressed gene in mouse prostate cancers that appears to suppress immune system cells.

The journal retracted the paper following an investigation into author Stephanie K. Watkins, then a postdoctoral fellow at the National Cancer Institute. According to a NIH press release released about the study in March 2011, the work “has led to the submission of a patent application by the NIH on behalf of Hurwitz and Watkins to target FOXO3 as a way to boost immune responses in cancer and to silence excessive immune responses in autoimmune diseases.” We found an NIH record of the patent application, but no record of an approved patent at the United States Patent and Trademark Office under either Hurwitz or Watkins’ names.

The paper has been cited 62 times, according to Thomson Scientific’s Web of Knowledge. Here’s the full notice: Continue reading NIH cancer paper retracted for faked data

NIH neuroscientist loses second paper, again the result of first author misconduct

Stanley Rapoport. Source: NIH
Stanley Rapoport. Source: NIH

Stanley Rapoport, a neuroscientist in the National Institute on Aging, isn’t having a lot of luck with his first authors. One committed misconduct and cost him a paper in the journal Age last year, and now he’s lost another paper with a different first author, but for the exact same reason.

The latest paper, in Neurochemical Research, examined whether chronic doses of aspirin reduce brain inflammation. It has been cited 14 times, according to Thomson Scientific’s Web of Knowledge.

Here’s more from the note: Continue reading NIH neuroscientist loses second paper, again the result of first author misconduct