Category: image manipulation

Stem cell researchers fix two papers following PubPeer comments

Screen Shot 2016-04-13 at 5.56.09 PMA pair of stem cell researchers have earned two corrections, the result of images that were mislabeled, distorted, or compiled incorrectly, according to the notices.

Kang Cheng prepared the gels when he was a research fellow in last author Sanjeev Gupta‘s lab at the Albert Einstein College of Medicine. Gupta told us he reviewed the original gels, and the errors didn’t affect the conclusions in the papers, which were reproducible. He noted he believes the problems are the result of honest mistakes:

The errors did not confer any benefits whatsoever either for the papers or for Dr. Cheng.

On PubPeer, commenters have raised questions about the now corrected papers — along with several others on which Gupta is the senior author, but Cheng is not a co-author.

Edward Burns, research integrity officer at Einstein, told us that the medical school looked into an allegation of misconduct against Gupta:  

Continue reading Stem cell researchers fix two papers following PubPeer comments

Plant biologist’s paper pulled for falsification, three more questioned on PubPeer

PMBP Cover ImagePhysiology and Molecular Biology of Plants has retracted a paper about using Darjeeling tea clones against abiotic stress for problems with one of the figures.

The specific problem: “falsification/fabrication” of data underlying the figure, which the corresponding author — Sauren Das from the Indian Statistical Institute in Calcutta, West Bengal — couldn’t resolve. Das told us he denies the allegations made by the journal.

Meanwhile, three other papers by Das have been questioned on PubPeer. 

Let’s take a look at the retraction note: Continue reading Plant biologist’s paper pulled for falsification, three more questioned on PubPeer

Team in Japan earns third retraction for misconduct

JSRA team of researchers has earned its third retraction after an investigation at Oita University in Japan found instances of misconduct in their research.

The most recent notice mentions the investigation, and specifies that the first author, Satoshi Hagiwara, was responsible for the problematic figures in the paper. Hagiwara is also the first author on two retracted papers we reported on last year; one of the earlier retractions also mentions the investigation, but does not assign responsibility to any particular author. All three papers share three authors.

The retraction notice for “Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model,” published in the Journal of Surgical Research, explains the issues with the paper:

Continue reading Team in Japan earns third retraction for misconduct

Retraction count for Shigeaki Kato climbs to 39

Shigeaki Kato
Shigeaki Kato

We’ve found another retraction for Shigeaki Kato, number seven on our leaderboard.

Our count for Kato has now risen to 39; we added five retraction notices to our count for Kato last month. These notices follow an investigation at the University of Tokyo, where Kato used to work, which found 43 papers contained “likely altered or forged materials,” according to a 2013 news article from The Asahi Shimbun.

Here’s the retraction note for “1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP271B1 gene,” published in Molecular and Cellular Endocrinology:

Continue reading Retraction count for Shigeaki Kato climbs to 39

One in 25 papers contains inappropriately duplicated images, screen finds

Elies Bik
Elies Bik

Elisabeth Bik, a microbiologist at Stanford, has for years been a behind-the-scenes force in scientific integrity, anonymously submitting reports on plagiarism and image duplication to journal editors. Now, she’s ready to come out of the shadows.

With the help of two editors at microbiology journals, she has conducted a massive study looking for image duplication and manipulation in 20,621 published papers. Bik and co-authors Arturo Casadevall and Ferric Fang (a board member of our parent organization) found 782 instances of inappropriate image duplication, including 196 published papers containing “duplicated figures with alteration.” The study is being released as a pre-print on bioArxiv.

An example the paper uses of “duplication with alteration” is this Western blot where a band has been duplicated: Continue reading One in 25 papers contains inappropriately duplicated images, screen finds

Cancer researcher earns 3 more retractions following NIH misconduct investigation

A researcher formerly based at the National Cancer Institute has earned three new retractions following an investigation that found she committed misconduct.

In May of last year, Stephanie Watkins, who now works at Loyola Medicine, earned one two retraction, which mentions a review by an investigation committee at the National Institutes of Health. Two of the new notes, published in Cancer Research, mention the review as well, and cite data falsification in a figure as the reason for retraction. Watkins is the only author that did not agree to those retractions.

There may be more changes to the literature — an editor at another cancer journal told us the journal is awaiting a decision from the Office of Research Integrity before deciding what to do with a paper by Watkins, given that she does not agree with the misconduct charges.

We’ll start with a retraction note from Cancer Research:

Continue reading Cancer researcher earns 3 more retractions following NIH misconduct investigation

Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Gizem Domnez
Gizem Donmez

A well-known scientist at the Massachusetts Institute of Technology who studies longevity has retracted a paper for “numerous examples of unindicated splicing of gel lanes,” as well as other problems.

This is Leonard Guarente‘s second retraction. He shares both with Gizem Donmez, an alum of his lab who now has three retractions. Donmez left her post as a Tufts professor in 2014.

Guarente told us in March — when we reported that he’d published a mega-correction on another paper — that he had planned to address issues with the paper, “SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones,” published in the The Journal of Neuroscience. Now, a retraction note has appeared “at the request of the authors.” It explains:

Continue reading Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Does this scientific image look familiar? It’s from a catalog

cover (4)There’s something strange about a 2008 paper on the role of nicotine receptors in promoting lung cancer: One of the western blot analyses looks like a version of an image from a commercial catalog.

A commenter on PubPeer pointed out the similarities between an image in “Role of α7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation,” which was published in Cell Proliferation, and one used to promote an enzyme sold by Cell Signaling Technology.

Unfortunately, if the images are indeed the same, we can’t tell for certain who copied from whom. But a representative of the company told us it generates its own images, and this one was likely created before the paper was published. The last author — for whom we’ve found three other retractions — denied that the paper copied the image.

Here’s the panel from the paper, which was published in 2008: Continue reading Does this scientific image look familiar? It’s from a catalog

Authors pull 14-year-old paper from PNAS over concerns of fabrication

13.coverAuthors have retracted a 2002 paper from PNAS because part of a figure “may have been fabricated,” and they no longer have the original data to prove otherwise.

The paper in question, “Deficient Smad7 expression: A putative molecular defect in scleroderma,” studied the signaling pathways that may underlie the autoimmune disease. It has been cited 198 times, according to Thomson Reuters Web of Science.

The authors, led by Pascal J Goldschmidt-Clermont, currently the Dean of the School of  Medicine at the University of Miami, have issued a retraction note, which appeared online yesterday: Continue reading Authors pull 14-year-old paper from PNAS over concerns of fabrication

Concerns about image manipulation? Sorry, the data were lost in a flood

1 (1)Lost your data? Blame nature.

Microchimica Acta has retracted a paper about water-soluble quantum dots after the authors couldn’t provide back-up for a figure that contained signs of manipulation. The reason, the editor told us: The corresponding author said the raw data were lost in a flood in Sri Lanka.

The journal asked the authors for the data after an investigation suggested that the paper included copied pictures of the same nanoparticle. The paper is one of four by the pair of co-authors flagged on PubPeer for potential image duplication.

Here’s the retraction note for “CdS/ZnS core-shell quantum dots capped with mercaptoacetic acid as fluorescent probes for Hg(II) ions:”

Continue reading Concerns about image manipulation? Sorry, the data were lost in a flood