How a researcher’s request to correct one paper turned into 19 retractions

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Jin Cheng

Last year, a cancer researcher wrote to the Journal of Biological Chemistry, asking to correct one of his papers. The journal responded by requesting the raw data used to prepare his figures. Then, in a follow-up request, it asked for raw data behind the figures in 20 additional published articles.

And when all was said and done six months later, Jin Cheng ended up with far more than just a single correction: Last month, the journal issued withdrawals for 19 of his papers — including the paper he originally asked to correct — along with one correction.

We’ve pieced together some clues about what happened after reviewing correspondence between representatives of JBC and Moffitt Cancer Center, where Cheng conducted his research. A spokesperson for Moffitt confirmed that the retractions did not initiate from an institutional investigation — but that the institution is now conducting one.

That’s not the way retractions typically happen: Often, journals don’t have the resources to conduct investigations themselves, so institutions mostly take the lead in double-checking papers and, if necessary, contacting the journal to initiate a retraction. Here, it seems the opposite took place.

The Moffitt spokesperson also told us that Continue reading How a researcher’s request to correct one paper turned into 19 retractions

Nature Cell Biology retracts hotly debated cancer paper

ncbLast week, we learned a 2016 paper heavily discussed on PubPeer might be retracted — today, we learned that Nature Cell Biology has indeed pulled the paper, citing inappropriate image modifications.

As we reported last week, a comment on PubPeer flagged as coming from an author said they had requested a retraction. A representative of National Taiwan University (NTU) told us the first author had resigned, and the paper was under investigation — an investigation which included the last author, a prominent researcher who is also a vice president at another institution in Taiwan.

Here’s Nature Cell Biology‘s official statement about the paper, in the form of a retraction notice that appears to be written by the authors:  Continue reading Nature Cell Biology retracts hotly debated cancer paper

Details of investigative report into Sarkar released by ACLU

Fazlul Sarkar
Fazlul Sarkar

We knew that Wayne State University had investigated allegations of misconduct against Fazlul Sarkar, the scientist who is suing PubPeer commenters over criticisms of his work. We knew The Scientist had obtained a copy of the report, which concluded he had engaged in widespread misconduct, and he should retract more than 40 papers.

And now, thanks to the American Civil Liberties Union, which is representing PubPeer in court and has filed a motion to include the report as evidence in the case, we have a copy.

It’s a long read, but here are some highlights:

Continue reading Details of investigative report into Sarkar released by ACLU

Nature Cell Bio paper may be headed for retraction

ncbA Nature Cell Biology paper published only a few months ago by prominent researchers in Taiwan has sparked a heated discussion on PubPeer, which now includes a comment allegedly from an author saying they have requested its retraction.

Although a representative of the journal wouldn’t confirm to us that the authors had requested a retraction, the comment on PubPeer says the paper contains several figures that were “inappropriately manipulated” by the first author.

Here’s the full comment on PubPeer, tagged as coming from one of the authors of the paper:

Continue reading Nature Cell Bio paper may be headed for retraction

Two Harvard-led groups pull well-cited cancer papers for duplication

the-journal-of-clinical-investigationTwo sets of authors based largely at Harvard Medical School have each retracted a paper for duplication in the same journal.

Both papers — which are more than a decade old — were pulled in The Journal of Clinical Investigation on November 1 by their respective corresponding authors.

One paper’s last author told us it was difficult to identify how the duplications occurred since the study took place so long ago, but added that multiple experiments had corroborated the results.

Here’s the first retraction notice for “Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism:” Continue reading Two Harvard-led groups pull well-cited cancer papers for duplication

Prominent researcher in Scotland resigns after misconduct finding upheld

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Robert Ryan

A rising star in the field of infectious disease has resigned from the University of Dundee in Scotland after the university upheld the findings of an investigation concluding that he committed misconduct.

Earlier this year, Robert Ryan was suspended amidst the investigation, which focused on data doctoring in several publications. We’ve now been forwarded an internal email from Julian Blow, dean of the School of Life Sciences, which alerts staff that Ryan has resigned, and the institution has upheld its finding of misconduct, despite Ryan’s appeal.

In 2015, Ryan was selected to be an EMBO Young Investigator; yesterday, EMBO announced that it had withdrawn him from the program.

Blow’s email to staff, dated November 9, states:

Continue reading Prominent researcher in Scotland resigns after misconduct finding upheld

Eye researcher loses fourth paper for misconduct following Georgia, VA investigation

Azza B. El-Remessy
Azza B. El-Remessy

A biologist at the University of Georgia has lost a paper after an investigation revealed she had tampered with three images.

In 2014, Azza El-Remessy notched three retractions for a series of image errors. Now, a fourth retraction notice, and an expression of concern, explain there has been an investigation into her work. The investigation — conducted by two Georgia institutions, along with the Charlie Norwood Veterans Affairs Medical Center, where El-Remessy has additional appointments — has found evidence of misconduct.

The retraction notice for “Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration” explains:

Continue reading Eye researcher loses fourth paper for misconduct following Georgia, VA investigation

Leading diabetes researcher acted negligently, probe concludes

Kathrin Maelder
Kathrin Maedler

Several duplications in the work of a prominent diabetes researcher were the result of negligence, but there is not enough evidence to support charges of misconduct, according to an investigation at her university in Germany.

Recently, we’ve reported on several notices for papers co-authored by Kathrin Maedler, a researcher at the University of Bremen. So far, Maedler has one retraction, multiple corrections, and two expressions of concern to her name, after several of her papers were questioned on PubPeer. Previously, the University of Zurich in Switzerland — where Maedler completed her PhD in 2002 — determined there was a lack of evidence to support allegations of misconduct in papers that were part of her doctoral thesis. 

Last week, the University of Bremen released its own investigation report (in German), which we translated using One Hour Translation. It concludes that Maedler Continue reading Leading diabetes researcher acted negligently, probe concludes

Author pulls Diabetes paper with duplicated Western blots

diabetesA researcher has retracted a paper from Diabetes after re-using some Western blots in one of the figures from other papers.

According to the retraction notice, the first and corresponding author — Eric Berglund, formerly at Vanderbilt University in Nashville, Tennessee — contacted the journal himself to report the error, for which he takes full responsibility.

Here’s the retraction notice: Continue reading Author pulls Diabetes paper with duplicated Western blots

Prominent heart researcher dismissed by Ontario university; colleagues appeal

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Morris Karmazyn

Earlier this month, Morris Karmazyn, an award-winning cardiovascular researcher who’s published hundreds of papers, was called into a meeting with the office of faculty relations at the University of Western Ontario, and terminated.

The reason? A series of image problems in some of his papers, raised by a former member of his lab. When Karmazyn, Canada Research Chair in Experimental Cardiology, was told it was a case of “misconduct,” he was floored: Continue reading Prominent heart researcher dismissed by Ontario university; colleagues appeal