Two journals retracting papers from University of Malaya featuring widely criticized figures

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that excited Twitter

One journal has retracted a paper containing images that recently raised suspicions of obvious duplications, and another journal is planning to do the same.

Scientists first leveled accusations against the newly retracted paper in Scientific Reports, along with two others by the same researchers, earlier this month on Twitter. One other journal — PeerJ — has announced that it plans to retract one of the questioned papers, as well. The third paper, in Frontiers in Pharmacology, bears an expression of concern.

It was unusually quick action on the part of the journals, as well as the authors’ host institution, the University of Malaya, which announced last week the authors had manipulated figures in all three papers, along with one other.

Here’s today’s retraction notice from Scientific Reports for “Novel piperazine core compound induces death in human liver cancer cells: possible pharmacological properties:”

Continue reading Two journals retracting papers from University of Malaya featuring widely criticized figures

Highly cited cancer researcher logs 8th, 9th retractions

Bharat Aggarwal
Bharat Aggarwal

Bharat Aggarwal, a highly cited cancer researcher who retired last year from MD Anderson, has logged two retractions following an investigation into his work, bringing his total to nine.

Aggarwal has threatened to sue us in the past, and told us that MD Anderson has been investigating his work. Earlier this year, Biochemical Pharmacology retracted seven studies of which he is the only common author, noting the “data integrity has become questionable.” Now, he’s earned two more retractions in Molecular Pharmacology, both for “inappropriate” or “unacceptable” image manipulation.

Both of the notices are paywalled (tsk, tsk). Here’s one for “Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells:” Continue reading Highly cited cancer researcher logs 8th, 9th retractions

Leiden requests two retractions over misconduct

logo-lumc-engThe Leiden University Medical Center (LUMC) has asked a journal to retract two papers after revealing a former employee manipulated data.

The report does not name the individual nor the journal, but notes that they work in a molecular field, and are currently employed by a university outside The Netherlands.

According to a news release about the report: Continue reading Leiden requests two retractions over misconduct

Figures questioned online were manipulated, says Malaysia investigation

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that set Twitter abuzz: Figure 6 from the Scientific Reports paper, in which every cell in each stage of cell death appeared to be an exact copy.

Many figures in four papers by a research team in Malaysia contain duplication or manipulation, a university committee has found, calling for multiple retractions.

We learned about issues with three of the papers, including one in Scientific Reports, earlier this week when they were the talk of Twitter. As journals issued expressions of concern, and an expert wondered how the papers passed peer review at all, the first author, a researcher at the University of Malaya (UM), denied allegations of duplication.

UM was alerted to allegations of misconduct in the Scientific Reports paper last Saturday, and according to a statement published today:

Continue reading Figures questioned online were manipulated, says Malaysia investigation

Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Screen Shot 2016-06-15 at 9.17.15 AMMultiple investigations have been launched into allegations of blatant duplications by a research group in Malaysia.

Last week, users alleged on Twitter that three papers by the same team included pictures of cells that were copied and pasted. First author Nima Samie, affiliated with University of Malaya in Malaysia, denied the accusations — but both the Malaysian government and now two journals sees cause for further investigation.

Frontiers in Pharmacology published an expression of concern this morning:

Continue reading Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Author denies accusations of blatant duplication

NPGTwitter is abuzz today over allegations that a recent paper in Scientific Reports contains a blatant example of duplication.

According to the allegations, a group of researchers in Malaysia have used the same four images to represent some 30 cells at different stages of cell death. One researcher has even suggested the allegedly doctored images appear in three different papers.

Is this a manipulated image? See for yourself:

Continue reading Author denies accusations of blatant duplication

Prompted by PubPeer, biologist corrects three papers

GeneA biologist has corrected three papers that are nearly a decade old, after concerns were raised on PubPeer.

A commenter first posted a comment about an image in one of the papers in 2013; after more comments on other papers appeared in November 2015, author Zoya Avramova at the University of Nebraska-Lincoln received emails alerting her to the threads. She has responded, including to the 2013 comment, noting “the said images should have been assembled more carefully.”

After repeating some of the experiments to verify the results, she has now issued corrections on three papers, about the genetics of model organism Arabidopsis. The papers share a first author, Abdelaty Saleh, who was a postdoc in Avramova’s lab at the time of the work.

The correction notice for “Dynamic and stable histone H3 methylation patterns at the Arabidopsis FLC and AP1 loci,” appearing in the July 2016 volume of Gene, explains:  Continue reading Prompted by PubPeer, biologist corrects three papers

Authors reused images in three papers, concludes journal probe

JBCBiologists are retracting three papers after the journal concluded they contain reused images, designed to represent different experiments. The authors stand by the conclusions, some of which they say have been “extensively validated.”

The Journal of Biological Chemistry used image analysis software to evaluate the images, first published at least a decade ago. Unfortunately, the raw data behind the problematic images were not available. The authors have also corrected a fourth paper in another journal, and wrote on PubPeer that they are working with journals to address concerns in three more.

The papers share two authors: Mireia Duñach at the Autonomous University of Barcelona, and Antonio García de Herreros at the Institut Hospital del Mar d’Investigacions Mèdiques. A representative of the Institut Hospital del Mar d’Investigacions Mèdiques told us it is looking into Garcia de Herreros’s work.

We’ll start with “β-Catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to β-catenin,” which has been cited 45 times since it was published in 2002, according to Thomson Reuters Web of Science. The retraction notice says:

Continue reading Authors reused images in three papers, concludes journal probe

Poll: Is duplication misconduct?

RW logoIf authors duplicate portions of their own work in multiple papers — such as descriptions of methods, a boilerplate background to their field, etc. — should that be considered misconduct?

Of course, to many journals, duplication — also known as “self-plagiarism” is a retractable offense. A recent letter to the U.S. Office of Research Integrity (ORI) from the Council on Governmental Relations asked the agency to consider it misconduct, and “include self-plagiarism in the definition of plagiarism.” More specifically, the letter — reported by the Report on Research Compliance — says to new ORI director Kathy Partin:

Continue reading Poll: Is duplication misconduct?

Two math papers are too similar, both retracted

Advances in Differential EquationsA mathematician has lost two publications that overlap substantially.

In this case, it’s easy to see how editors were duped (as it were). Both journals received the papers within a few months of each other, and then published them in quick succession; both have since been retracted. The papers share a first author, Jin Li, affiliated with Jiujiang University in China.

How similar are Li’s papers? See for yourself.

Here’s the abstract for “Landesman-Lazer type condition for second-order differential equations at resonance with impulsive effects,” received by Advances in Difference Equations in June 2014 and published in September 2014: Continue reading Two math papers are too similar, both retracted