Category: data issues

Misconduct dissolves paper on possible clot-busters

amclct_v006i002.inddDrug researchers in India have lost their 2013 paper in ACS Medicinal Chemistry Letters because the first author fabricated findings.

The article, by a group from the Maharaja Sayajirao University of Baroda, Vadodara, in Gujarat, was attempting to synthesize and screen novel clot-busting drugs; one compound exhibited the same activity as aspirin or warfarin, but without increasing bleeding time.

Sadly, it appears as if this potential medical advance was not to be. Here’s the retraction notice for “Novel 2-Aminobenzamides as Potential Orally Active Antithrombotic Agents”: Continue reading Misconduct dissolves paper on possible clot-busters

Chinese heavy metal contamination paper purged for data theft

Environmental_Monitoring_and_AssessmentAn environmental journal has retracted a paper about pollution in China after it discovered the authors lifted the dataset from another group.

The authors of the study — which chronicled the degree of heavy metal pollution on the banks of the Pearl River Delta — didn’t have permission to use the data. Environmental Monitoring and Assessment‘s notice doesn’t suggest the data are inaccurate.

The heavy metals in the soil come from the many manufacturing plants in the area, including those that provide the West with blue jeans, phones, and other electronics. The pollutants’ effects are wide-reaching: According to the South China Morning Post, industrial outfits discharge huge volumes of toxic chemicals into the Pearl River, including arsenic, copper, cadmium, and mercury.

Continue reading Chinese heavy metal contamination paper purged for data theft

Sun sets on Sun Yat-sen University cell bio paper

j cell scienceResearchers at Sun Yat-sen University in China have lost a paper in the Journal of Cell Science for “inappropriate figure manipulations,” which they blame entirely on the first author.

According to the notice, three figures were “inappropriately modified” — cells or nuclei were moved, and the edges of cell images were trimmed. The researchers place the responsibility on first author Liping Chen, claiming that “her co-authors were completely unaware.”

The modifications didn’t affect the conclusions, the note says, but after an investigation by Sun Yat-sen University, the journal decided to retract the paper. Liping Chen says she “regrets the inappropriate figure manipulations,” according to the note.

Continue reading Sun sets on Sun Yat-sen University cell bio paper

Heart journal issues expression of concern after fraud report

circulationThe American Heart Association’s journal Circulation has issued an expression of concern for a paper about the molecular underpinnings of arrhythmias that was co-authored by a biomedical engineer who committed fraud on a massive scale.

According to an investigation by the Office of Research Integrity (ORI), former Vanderbilt engineer Igor Dzhura faked nearly 70 images and drastically over-estimated the number of experiments he conducted. He was banned from receiving federal funding for three years.

The fraud has resulted in six retracted papers, Dzhura has agreed to retract six papers, which have been cited more than 500 times. [Ed. note: at this time, only one paper has actually been retracted]

Continue reading Heart journal issues expression of concern after fraud report

Ob-gyn prof up to 7 retractions, latest due to “substantial data misrepresentation”

University of Florida
University of Florida

Two more retractions have popped up for Nasser Chegini, the former University of Florida professor currently under investigation by the Office of Research Integrity (ORI).

Both retractions appear in the Journal of Clinical Endocrinology & Metabolism. The notices indicate that an investigation report from the University of Florida “found substantial data misrepresentation” in two JCEM articles about Smads, signaling molecules that carry messages from TGF-beta receptors to the nucleus.

Here’s the notice for “The Expression of Smads in Human Endometrium and Regulation and Induction in Endometrial Epithelial and Stromal Cells by Transforming Growth Factor-Beta” (cited 28 times, according to Thomson Scientific’s Web of Knowledge):

Continue reading Ob-gyn prof up to 7 retractions, latest due to “substantial data misrepresentation”

Neuro journal pulls comatose brain abstract due to “several mistakes”

clinical neurophysiologySwiss researchers have retracted an abstract in Clinical Neurophysiology because only one of them actually knew about the paper — and what he submitted had “several mistakes.”

The abstract, about electric impulses in the brain of comatose patients, originally appeared as a poster at the June 2014 joint meeting of multiple Swiss neuroscience societies. It was submitted by first author Alexandre Simonin, who lists his affiliation as the University Hospital of Lausanne, a Swiss hospital.

The meeting proceedings ran in the October issue of Clinical Neurophysiology. Besides the issues of authorship and errors, the notice also says the abstract “potentially conflicts with another publication,” suggesting the data might have already appeared in a paper.

Here’s the notice for “P02. Predicting the outcome of post-anoxic comatose patients based on single-trial EEG analysis”: Continue reading Neuro journal pulls comatose brain abstract due to “several mistakes”

Stats mistake crashes bike accident paper

Image via Thomas Hawk
Image via Thomas Hawk

Two researchers at the University of Saskatchewan in Canada have retracted a paper that came to fairly common-sense conclusions about bike safety.

In the September 2014 issue of the Journal of Transport and Health, the authors concluded that slippery road surfaces, night-time biking, and higher speed limits were all associated with higher probabilities of a bicycle accident.

Despite these logical conclusions, the authors discovered a statistical error that “would significantly change the discussion,” according to the retraction notice.

Continue reading Stats mistake crashes bike accident paper

Science chemistry paper earns retraction after expression of concern, marking second for UT group

scienceThe authors of a 2011 Science paper that proposed a new way to direct chemical bonds have withdrawn the paper after concerns about the data prompted an investigation and Editorial Expression of Concern last year from the journal. The retraction is the second for the group, which has also had seven other expressions of concern.

After a reader emailed the editors to raise suspicions about the data, corresponding author Christopher W. Bielawski, then based at the University of Texas at Austin, led an investigation of all the figures. It found substantial problems: “In over 50% of the figure parts, the authors deemed the data unreliable due to uncertainty regarding the origin of data or the manner in which the data were processed,” according to the retraction notice.

UT Austin concluded that there had been misconduct, but did not elaborate.

Continue reading Science chemistry paper earns retraction after expression of concern, marking second for UT group

Misconduct forces retraction of health behavior paper

j behav medA pair of psychology researchers at West Virginia University have lost their 2013 article in the Journal of Behavioral Medicine after one of the authors was found to have cooked the data.

The paper, “Preference for immediate reinforcement over delayed reinforcement: relation between delay discounting and health behavior,” was written by Shane Melanko and Kevin Larkin. It examined whether people who place less importance on the future were also less likely to adopt healthy behaviors, which come with delayed benefits. Melanko, then a doctoral candidate under Larkin, was evidently at one time a psychology student of some promise.

That promise might go unfulfilled. According to the retraction notice: Continue reading Misconduct forces retraction of health behavior paper

Matlab mixup sinks Journal of Neuroscience paper

journal of neuroscienceA team of neuroscientists at University of Oregon and the University of California, San Diego (UCSD) have retracted a paper from The Journal of Neuroscience after realizing their analytic code contained an error.

The authors state in the notice that their conclusion remains accurate after correcting the mistake in the program Matlab. However, the paper — which examined the role of neuronal oscillations in working memory — still contained “some findings that we no longer believe to be robust.”

It’s a very useful notice: Continue reading Matlab mixup sinks Journal of Neuroscience paper