Category: data issues

Former Florida ob-gyn prof notches eighth retraction

University of Florida
University of Florida

Nasser Chegini, the former University of Florida professor currently under investigation by the Office of Research Integrity (ORI), has now had eight papers retracted.

The eighth paper, in the journal Reproductive Biology and Endocrinology, is about the effect of a compound used during fertility treatments on Smads, signaling molecules that carry messages from TGF-beta receptors to the nucleus. It’s being retracted disappeared due to the discovery of data that “have been fabricated or falsified by the last author” — namely, Chegini.

Here’s more from the notice for “Gonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cells:” Continue reading Former Florida ob-gyn prof notches eighth retraction

Urology researcher in Iran up to six retractions

safarinejadA urologist in Iran has lost three papers in BJU International, bringing his retraction count to a half-dozen.

In December 2013, we reported on three retractions by Mohammad Reza Safarinejad. None of those notices, about papers related to incontinence and erectile dysfunction, made the reasons for retraction very clear. After that post ran, Safarinejad told us that Hartmut Porst, former president of the European Society for Sexual Medicine, had raised questions about the data in a number of his papers. Porst confirmed that for us earlier this month.

All of the latest papers, about aspects of male sexual dysfunction, are being retracted due to “inappropriate” statistical analyses.

Here’s the notice for “Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation,” which has been cited 17 times, according to Thomson Scientific’s Web of Knowledge: Continue reading Urology researcher in Iran up to six retractions

Gynecologic cancer researcher earns eighth retraction

Screen Shot 2015-04-02 at 5.50.31 PMNoriyuki Takai, a gynecologic cancer researcher in Japan, has notched one more retraction — bringing the total to eight — due to figures that were “processed inappropriately” and did “not accurately report the original data.”

According to the notice, Takai alone put the figures together in the 2006 Oncology paper, which tested a histone deacetylase inhibitor on endometrial and ovarian cancer cell lines. The team is part of the department of obstetrics and gynecology at Oita University in Japan.

Takai lost four papers in 2013 in Cancer Letters, and three papers in 2012 in Gynecologic Oncology, also due to issues with figures.

Continue reading Gynecologic cancer researcher earns eighth retraction

Stats error has chilling effect on global warming paper

global change biologyIt turns out a 2014 paper that found a surprising pattern of plant migration in response to global warming was not so surprising after all — it’s been retracted by the authors due to a mistake in the statistical analysis.

Most studies on migrating populations have found that species around the globe move north to escape the rising temperatures. But the authors of the 2014 paper in Global Change Biology found the opposite — according to their analysis, many plant species in Western North America had been migrating south, toward warmer climates.

The lead author Melanie Harsch told Science in 2014 that the team had been suspicious of the analysis, and so ran it twice: Continue reading Stats error has chilling effect on global warming paper

Second paper for Duke lung researchers expires in a retraction

pnas 3 5 13Scientists at Duke and the National Institutes of Health have retracted a PNAS paper on asthma treatment after realizing the data from two sources didn’t match, and “most primary data” from several experiments were missing.

The mix up seems to have come from the pulmonary function laboratory that tested how well asthmatic patients’ lungs were functioning on an experimental anti-inflammatory therapy. As the authors say in the retraction note: Continue reading Second paper for Duke lung researchers expires in a retraction

Slippery slope? Data problems force retraction of landslide paper

The Mameyes Landslide, in Puerto Rico, buried more than 100 homes in 1985. Source: USGS
The Mameyes Landslide, in Puerto Rico, buried more than 100 homes in 1985. Source: USGS

The authors of a 2014 paper in The Scientific World Journal on rock slopes have retracted their article for “erroneous” data.

The paper, “Slope Stability Analysis Using Limit Equilibrium Method in Nonlinear Criterion,” came from a group of researchers from institutions including the Changjiang River Scientific Research Institute in Wuhan, and the Key Laboratory of Transportation Tunnel Engineering at Southwest Jiaotong University in Chengdu. It’s about (we think) how to calculate the safety of rock slopes, and how vulnerable they are to landslides.

Here’s the notice, which as a pretty fair ratio of words to information:

Continue reading Slippery slope? Data problems force retraction of landslide paper

Journal retracts part of molecular bio paper due to “unsubstantiated conclusions”

j mol evAll but one of the authors of a 2013 Journal of Molecular Evolution paper have requested a partial retraction due to “erroneous data” and “scientific misconduct” on the part of the remaining author.

The note blames second author Michael Kolesnikov for falsifying data on the formation of ATP. According to the notice, the misconduct was confirmed by a “thorough investigation” by the Bach Institute of Biochemistry in Russia, which no longer employs Kolesnikov.

Here is the note for “Abiotic Photophosphorylation Model Based on Abiogenic Flavin and Pteridine Pigments”: Continue reading Journal retracts part of molecular bio paper due to “unsubstantiated conclusions”

“Serious and obvious mistakes” kill paper on heart attacks in rats

j card pharmA group of researchers in China and the United States have retracted a 2014 paper in the Journal of Cardiovascular Pharmacology after discovering the data were fatally flawed.

The article examined whether the anti-arrhythmia drug zacopride affected cardiac remodeling after heart attack, and came from Bo-We Wu, of Shanxi Medical University, in Taiyuan, and colleagues, including one author from Savannah, Georgia.

Here’s more from the notice for “Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction”:

Continue reading “Serious and obvious mistakes” kill paper on heart attacks in rats

Drug paper gets a fix, notching several corrections

rsc_tb_1_3_COVER.inddThe Journal of Materials Chemistry B has issued a laundry list of corrections for a 2014 chemotherapy paper, which address re-use of “some text”, incorrectly stated doses, and miscalculations of the drug concentration, among other issues.

The paper described a new way to deliver gemcitabine via nanoparticles, focusing the drug on the tumors.

It turns out the authors’ focus wasn’t so clear when writing the paper. The researchers, at the Chinese Academy of Medical Science, Peking Union Medical College, and Tianjin University in China, said they used “some text” from two 2013 papers by a team of French oncologists “without appropriate attribution,” as well as repeatedly getting the in vivo dose wrong. The manuscript also contained several incorrect calculations of the “drug loading,” or the proportion of active drug.

Here’s the correction for “Tailor-made gemcitabine prodrug nanoparticles from well-defined drug–polymer amphiphiles prepared by controlled living radical polymerization for cancer chemotherapy” (free, but requires sign-in): Continue reading Drug paper gets a fix, notching several corrections

Data “irregularities” sink paper on water treatment

desal water treatmentDesalination and Water Treatment has retracted a paper it published in January by a pair of Turkish researchers for “irregularities in the methodology and data management.”

The article, “Molecular simulation of Zn2+, Cu2+, Pb2+, and NH4+ ion-exchange in Clinoptilolite,” investigated how well different natural forms of the zeolite Clinoptilolite remove heavy metals from wastewater. It came from the lab of Mehmet Göktuğ Ahunbay, of Istanbul Technical University, accompanied by first author Barış Demir.

According to the notice: Continue reading Data “irregularities” sink paper on water treatment