Duplication, “manipulated” data send carpal tunnel paper down black hole

ArchOrpthoak20The Archives of Orthopaedic and Trauma Surgery has retracted a study about whether developing fistula puts hemodialysis patients at higher risk of carpal tunnel syndrome because it “duplicated substantial parts” and “manipulated some original data” from a study by other researchers.

The retraction notice says it all: Continue reading Duplication, “manipulated” data send carpal tunnel paper down black hole

High-profile aging paper posts old erratum, requested by author more than one year prior

GenomeBioGenome Biology has partially retracted a high-profile paper about an epigenetic biomarker of aging – a year and a half after the author alerted the journal to a software coding error that invalidated one of its findings.

The paper, “DNA methylation age of human tissues and cell types,” garnered some media coverage and forms the basis of its author Steve Horvath‘s work on measuring human aging. It has been cited 73 times, according to Thomson Scientific’s Web of Knowledge. The article is also recommended on the post-publication peer review site Faculty of 1000.

The lengthy, peer-reviewed erratum notice, written by Horvath, refers to several figures and files, as well as a conclusion:

Continue reading High-profile aging paper posts old erratum, requested by author more than one year prior

“Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

IAIA team of Harvard and Yale biologists have retracted an Infection and Immunity paper due to data duplication.

After the duplication came to light, the erroneous figures were corrected using original data, but the results affected “some of the manuscript’s conclusions.” An ethics panel subsequently recommended retraction, according to the journal, and the authors agreed.

The paper, “NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection,” analyzed the role of the gene NOD2 in the lung inflammatory response against the bacteria Escherichia coli. It has been cited by 15 other papers, according to Thomson Scientific’s Web of Knowledge.

Figure 2B of the paper was previously corrected in 2012, but the retraction is for data duplication in figures 5F and 6A. Here’s the full retraction note: Continue reading “Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

“Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper

NatureNanoFollowing “significant concerns” raised by outside researchers and a formal university investigation, a group of authors in Taiwan has retracted a Nature Nanotechnology paper on DNA sequencing after they “could not reproduce the results of the work,” or even provide “a complete set of raw data for the original experiments.”

The paper, “DNA sequencing using electrical conductance measurements of a DNA polymerase,” describes a technology to sequence single DNA molecules — a technique that the authors, all based at National Chiao Tung University in Taiwan, suggest could be used to “cheaply and quickly” sequence DNA.

Concerns about the paper’s data were first raised in May 2013 by the community, according to an editorial from the journal. Then, the journal asked the university to investigate, says “Notes on a retraction”: Continue reading “Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper

Fungus among us, but what kind? Typing error spawns retraction for mushroom paper

natprodresAs every mushroom lover knows, weekend mycology is no sport for the lily-livered. Tasty species often look awfully like their deadly cousins. Turns out, typing can even be problematic for the experts.

Natural Products Research is retracting a 2014 paper on shelf fungus because… well, it wasn’t about shelf fungus after all.

The paper, “Chemical constituents: water-soluble vitamins, free amino acids and sugar profile from Ganoderma adspersum,” was written by Ibrahim Kivrak, a food chemist at Mugla Sitki Kocman University in Mugla, Turkey. It analyzed the nutritional components of G. adspersum, and found, per the abstract:

Continue reading Fungus among us, but what kind? Typing error spawns retraction for mushroom paper

More “unsubstantiated conclusions” partially sink another origin of life paper

OrigLife_ak17A trio of researchers based in Russia is asking to pull another set of figures and a table from a 2008 paper on modeling ATP formation after an investigation found the fourth researcher – the first author on the paper — “falsified or fabricated” the data they reflect.

The paper, in Origins of Life and Evolution of Biospheres, is the second partial retraction from many of the same authors for the same reason. Both journals also issued erratum notices, which read quite similarly. Here’s the latest note:

Continue reading More “unsubstantiated conclusions” partially sink another origin of life paper

“[T]hese things can happen in every lab:” Mutant plant paper uprooted after authors correct their own findings

FrontiersThree biologists at Tokyo Gakugei University in Japan have retracted a 2014 Frontiers in Plant Science paper on abnormal root growth in Arabidopsis “in light of new experimental evidence” showing they fingered the wrong mutant gene. The journal editors are hailing the retraction as an “excellent example of self-correction of the scientific record.”

The paper, “Mechanosensitive channel candidate MCA2 is involved in touch-induced root responses in Arabidopsis,” described the abnormally behaving roots of a mca2-null mutant Arabidopsis plant.

A subsequent string of experiments by the same research team—including DNA microarrays, RT-PCR, and a PCR-based genomic deletion analysis—demonstrated that two other mutations that somehow creeped into their experimental populations may have been to blame for the abnormal root behavior.

It’s a notably thorough and informative retraction notice from Frontiers, an open-access publisher with a history of badly handled and controversial retractions and publishing decisions. The notice describes the new experiments and the previous, erroneous results: Continue reading “[T]hese things can happen in every lab:” Mutant plant paper uprooted after authors correct their own findings

The “results should not be published:” Company confidentiality agreement squashes two insecticide papers

AMTWest Virginia University biologists have retracted two papers on insecticides for fruit pests due to a confidentiality agreement with a chemical manufacturer stating that the “results should not be published.”

The retracted 2014 articles in Arthropod Management Tests, “Control of Internal Lepidoptera and other insect pests in apple, 2013” and “Control of Oriental Fruit Moth and other insect pests in peach, 2013,” were written by WVU entomologist Daniel Frank and plant pathologist Alan Biggs.

We’ve been unable to find abstracts for the papers, but here is a sister paper Frank and Biggs published in 2012,“Control of Internal Lepidoptera and other insect pests in apple, 2012,” evaluating various insecticides for the control of internal lepidoptera on an experimental plot of Red Delicious apple trees in West Virginia.

Here’s the to-the-point retraction note, which is identical for each paper: Continue reading The “results should not be published:” Company confidentiality agreement squashes two insecticide papers

Scientists “wish to resign as co-authors:” Quantum dot paper retracted

chemcommChemical Communications has retracted a 2015 article by a group of researchers in China over concerns about fabricated data and an incredible shrinking list of authors.

The paper, “N, S co-doped graphene quantum dots from a single source precursor used for photodynamic cancer therapy under two-photon excitation,” was ostensibly written by nine researchers at the Collaborative Innovation Center for Marine Biomass Fiber, Materials and Textiles of Shandong Province, the Shandong Sino-Japanese Center for Collaborative Research of Carbon Nanomaterials, Laboratory of Fiber Materials and Modern Textiles, the Growing Base for State Key Laboratory at the  College of Chemical Science and Engineering at Qingdao University, and Mayo Clinic, in Rochester, Minn.

According to the abstract: Continue reading Scientists “wish to resign as co-authors:” Quantum dot paper retracted

Drunk rats paper wasted by “significant statistical errors”, among other issues

MolBiolRep_ak5Authors from Xinxiang Medical University in Weihui, China, are retracting a 2014 paper in Molecular Biology Reports because… well, because lots of things.

The researchers exposed nine rats to acute levels of alcohol then compared them to unexposed mice rats, noting differences in gene expression and molecular pathways.

But no one is toasting these findings anymore. Here are the details behind the retraction, courtesy of the notice:

Continue reading Drunk rats paper wasted by “significant statistical errors”, among other issues