Title: Effects of microRNA-223 on morphine analgesic tolerance by targeting NLRP3 in a rat model of neuropathic pain
What Caught Our Attention: Usually, an Expression of Concern (EOC) offers general language about “concerns regarding the validity of the data” or “concerns regarding the integrity of the study.” Here the language is anything but, saying that 54 Western blot bands within three figures have problems such as “visible pasted joints,” “square border,” and numerous “appear to be the same band.” According to the notice, the authors have not responded to requests for the original blots, so the editors are allowing the article to remain intact, choosing instead “to alert readers to these issues and allow them to arrive at their own conclusions regarding the figures.” Continue reading Caught Our Notice: 54 problems in three scientific images equals one expression of concern




Since the U.S. government launched a database of freely available journal articles in 2000, it has deselected roughly only 30 titles over concerns about journal quality. Fourteen of those titles were removed last August, all associated with one publisher — 