Authors retract striking circadian clock finding after failing to replicate

Screen Shot 2016-03-02 at 9.29.28 AMThe authors of a paper showing a “striking and unanticipated” relationship between light and temperature in regulating circadian rhythms are retracting it when the results couldn’t be replicated.

After being contacted by another group who couldn’t reproduce the data, the authors failed to, as well. They “have absolutely no explanation for the discrepancies with the original results,” according to the note in PLOS Biology.

It’s an unfortunate turn of events, but Continue reading Authors retract striking circadian clock finding after failing to replicate

Popular paper by famous longevity researcher gets mega-correction

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Leonard Guarente

A highly cited paper by a well-known scientist at the Massachusetts Institute of Technology who studies longevity could have aged better: The ten-year-old paper has earned its second correction.

It’s one of multiple papers by lead author Leonard Guarente that have been questioned on PubPeer. Guarente has already retracted one, and plans to address another. Continue reading Popular paper by famous longevity researcher gets mega-correction

PLOS ONE retracting paper that cites “the Creator”

Screen Shot 2016-01-19 at 10.50.25 AMPLOS ONE has retracted a paper published one month ago after readers began criticizing it for mentioning “the Creator.”

The article “Biomechanical Characteristics of Hand Coordination in Grasping Activities of Daily Living” now includes a reader comment from PLOS Staff, noting: Continue reading PLOS ONE retracting paper that cites “the Creator”

Sample tampering leads to plant scientist’s 7th retraction

Jorge Vivanco
Jorge Vivanco

Plant scientist Jorge Vivanco has earned his seventh retraction, after an investigation found data from soil samples were “intentionally fabricated by a third party.”

Vivanco and his former postdoc Harsh Bais made a name for themselves by discovering the secret behind a nasty invasive plant: It secretes a harmful form of catechin, which kills everything around it, suggesting it could serve as a new herbicide. The findings earned the researchers a story in the New York Times.

In the newly retracted paper, published in 2005, first author Laura Perry — then a postdoc at Colorado State University — further explored the role of the plant-killer, working with Vivanco as the last author. However, when a team working in the building next door had trouble finding catechin in their samples, Perry took another look, and concluded that her samples had been tampered with.

In other words, Perry told us:   Continue reading Sample tampering leads to plant scientist’s 7th retraction

Hands are the “proper design by the Creator,” PLOS ONE paper suggests

Screen Shot 2016-01-19 at 10.50.25 AMA paper about the biomechanics of human hands published last month in PLOS ONE is raising some questions on Twitter, after readers stumbled upon some curious language in the abstract:

The explicit functional link indicates that the biomechanical characteristic of tendinous connective architecture between muscles and articulations is the proper design by the Creator to perform a multitude of daily tasks in a comfortable way.

Yeah, that’s right — “the Creator.” You don’t see such language all that often in academic papers.

Not surprisingly, it’s prompted some harsh reactions from readers: Continue reading Hands are the “proper design by the Creator,” PLOS ONE paper suggests

High-profile critic slams Nature letters about dinosaur growth following corrections

cover_nature (1)Authors of a pair of letters in Nature that concluded dinosaurs reached their full size surprisingly quickly are standing by their conclusions, despite challenges from a high-profile critic.

In the letters, researchers led by first author Gregory M. Erickson, a paleobiologist at The Florida State University, concluded that massive dinos grew fast — for example, a 5.5 ton T-Rex could reach skeletal maturity in just two decades. However, when Nathan Myhrvold tried to reanalyze the data, he couldn’t replicate the results. The authors have issued corrections to address the small mistakes unearthed by Myhrvold’s analysis, but argue he couldn’t replicate their results because they hadn’t fully explained their methodology.

After Myhrvold attempted to replicate the findings of maximum size and growth rate for several papers, he found issues in many, including the two Nature letters, according to a press release on Myhrvold’s website: Continue reading High-profile critic slams Nature letters about dinosaur growth following corrections

Surgery studies lacked ethics committee approval

3Surgery Today has pulled a pair of papers that share many authors because the studies they describe were not approved by an institutional ethics committee.

One describes a case in which the researchers removed a mass from a 64-year-old woman’s small intestine; the other describes how the authors removed a growth from a patient’s pancreas. They conclude that the surgery techniques used — like a laparoscopic pancreaticoduodenectomy, a take on the “Whipple Procedure” — can be “feasible, safe, and effective” in certain patients.

The papers share several authors, including a first author, Akihiro Cho, whose affiliation on the papers is Chiba Cancer Center Hospital in Japan. They also share a retraction note, which explains how the journal learned of the issue:

Continue reading Surgery studies lacked ethics committee approval

Upon discovering several errors, authors retract gastric cancer paper

mmr_12_4After finding several errors in their paper about the molecular activity underlying gastric cancer, the authors unanimously decided to retract it.

According to the retraction note, three figures in the paper had β‑actin bands that were omitted, interchanged, or both.

The retraction note provides the details:

Continue reading Upon discovering several errors, authors retract gastric cancer paper

Journals flag 6 papers, request investigation of New Jersey university biologists

Two journals have published six expressions of concern for a pair of biologists at Rowan University, and are asking the university to undertake an investigation.

We contacted the editors of the two journals — Journal of Cell Science and Biology Open — who both said they decided to flag the papers after a reader raised concerns about potential re-use of blot images. The six papers are co-authored by John G. Pastorino, a molecular biologist at Rowan University in New Jersey and Nataly Shulga, whose LinkedIn identifies her as a research specialist at the same institution. According to the nearly identical notes, the journals (which share a publisher) undertook a review of the original data, but “felt unable to resolve this matter.”

The expressions of concern — five from the  Journal of Cell Science and one from Biology Open — include pretty much the same text. Here’s the note that appeared in JCS:

Continue reading Journals flag 6 papers, request investigation of New Jersey university biologists

STAP stem cell researcher Obokata loses another paper

Nature protocols

The first author of two high-profile Nature retractions about a technique to easily create stem cells has lost another paper in Nature Protocols.

Haruko Obokata, once “a lab director’s dream,” according to The New Yorker, also had her PhD revoked from Waseda University last fall.

After learning of concerns that two figures are “very similar” and “some of the error bars look unevenly positioned,” the rest of the authors were unable to locate the raw data, according to the note. The journal could not reach Obokata for comment before publishing the retraction.

Reproducible subcutaneous transplantation of cell sheets into recipient mice” has been cited 21 times, according to Thomson Reuters Web of Science. It was published in June 2011, soon after Obokata earned her PhD. 

Here’s the note:

Continue reading STAP stem cell researcher Obokata loses another paper