PNAS paper on potential breast cancer treatment retracted

The authors of a 2009 study in the Proceedings of the National Academy of Sciences (PNAS) have retracted the paper, which found a particular molecule could make breast tumors respond to a drug to which they’re not normally susceptible.

The paper — which has been cited five times, according to Thomson Scientific’s Web of Knowledge — was the subject of a fair amount of press coverage, although the molecule is not yet in clinical trials. In a Reuters story, lead author Caroline Ford said of the alleged tamoxifen-sensitizing compound, Foxy-5:

“It flips the switch basically,” Ford said in a telephone interview. “It makes breast cancer cells respond to tamoxifen in women who cannot be treated with the drug,” she added. “If you don’t have that molecule you can’t get tamoxifen because there is no target.”

According to the retraction notice, signed by all three of the study’s authors: Continue reading PNAS paper on potential breast cancer treatment retracted

Sultans of swap: List of plagiarized papers grows to include BMJ

Although some readers evidently have yawned at revelations that Vahdettin Bayazit, of Alparslan University in Turkey (and, we are tempted to assume, at least a few of his co-authors) appears to have plagiarized wantonly in numerous published articles, one follower of Retraction Watch was on to this case even before we were.

In an e-mail, the tipster laid out a picture of intellectual dishonesty audacious for both its scope and ham-handedness. The researcher, who wanted to remain anonymous, used Google to detect instances of plagiarism, just as we had, coming up with “more than 10” papers with passages stolen from the scientific literature and even Wikipedia, including not only lifted text but figures, too. And, just as in our case, the editors our source contacted about the misconduct have essentially ignored it.

We confess that we’re puzzled by the attitude that a little plagiarism is no big deal. As physician Andrew Burd writes in the BMJ today: Continue reading Sultans of swap: List of plagiarized papers grows to include BMJ

ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

The Office of Research Integrity has thrown a heavy book at Bengu Sezen, a former chemist at Columbia University, alleging that school and agency investigators turned up 21 instances of research misconduct by the disgraced scientist.

According to the agency: Continue reading ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

Sultans of swap: Turkish researchers plagiarized electromagnetic fields-cancer paper, apparently others

The Bosnian Journal of Basic Medical Sciences has retracted a paper it published in August by Turkish researchers on the potential cancer risks associated with exposure to electromagnetic fields, or EMFs.

The reason: Other people wrote nearly all of it.

According to an editor’s notice: Continue reading Sultans of swap: Turkish researchers plagiarized electromagnetic fields-cancer paper, apparently others

Update on a Best Of retraction: Elsevier edits notice suggesting renaming Israel “historical Palestine” was political

About two months ago, we posted an item on a curious retraction as the first installment in our Best of Retractions series. In the notice of the retraction in Agricultural Water Management, the editor wrote:

Reason: During the second revision of the manuscript, the authors modified Figure 1 (changing the label from “Israel” to  “Historical Palestine”), apparently with the goal of inserting a political statement into a scientific journal article. The authors did not inform the editors or the publisher of this change in their manuscript. As such, the authors have not lived up to the standards of trust and integrity that form the foundation of the peer-review process. The Editors-in-Chief take a very strong view on this matter and, hence, the retraction of the article from publication in Agricultural Water Management.

As Pieter van der Zaag, one of the paper’s authors informed us over the weekend in a comment on that post, however, the phrase “apparently with the goal of inserting a political statement into a scientific journal article” has now been removed from the notice. We asked van der Zaag, of the UNESCO-IHE Institute for Water Education, for some more information. Here are his comments: Continue reading Update on a Best Of retraction: Elsevier edits notice suggesting renaming Israel “historical Palestine” was political

After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician

Ludwigshafen Hospital, via Wikimedia http://commons.wikimedia.org/wiki/File:Klinikum_Ludwigshafen_Nordseite.jpg

Joachim Boldt, a leading German anesthesiologist who had a 2009 paper in Anesthesia & Analgesia retracted last month* amid allegations  that he had misrepresented parts of the study, has been relieved of his duties as chief physician at Ludwigshafen Hospital.

A press release from the German Society for Anesthesiology and Intensive Care Medicine (DGAI) condemns Boldt’s actions. The press release goes on (translated from German): Continue reading After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician

Plagiarists plagiarized: A daisy chain of retractions at Anesthesia & Analgesia

Self-plagiarism alert: A very similar version of this post is being published online in Anesthesiology News, where one of us (AM) is managing editor.

If a plagiarist plagiarizes from an author who herself has plagiarized, do we call it a wash and go for a beer?

That scenario is precisely what Steven L. Shafer found himself facing recently. Shafer, editor-in-chief of Anesthesia & Analgesia (A&A), learned that authors of a 2008 case report in his publication had lifted two-and-a-half paragraphs of text from a 2004 paper published in the Canadian Journal of Anesthesia.

A contrite retraction letter, which appears in the December issue of A&A, from the lead author, Sushma Bhatnagar, of New Delhi, India, called the plagiarism “unintended” and apologized for the incident. Straightforward enough.

But then things get sticky. Continue reading Plagiarists plagiarized: A daisy chain of retractions at Anesthesia & Analgesia

Best of Retractions Part III: Whatever can go wrong …

Paging Dr. Murphy.

In July, the editors of Cancer Biology & Therapy published a retraction remarkable for its scope. Apparently, nearly everything dishonest authors can do to doctor a manuscript, these authors did.

The paper, “Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma,” initially appeared on the journal’s website in January 2008. It came out in print three months later, in the April issue, and has been cited 8 times since, according to Thomson Scientific’s Web of Knowledge.

The authors were Song Zhang, Jian Xin Yue,  Ju Hong Yang, Peng Cheng Cai and Wei Jia Kong, of Huazhong University of Science and Technology in Hubei, China. It will be quite clear why we listed all those authors in a moment. Continue reading Best of Retractions Part III: Whatever can go wrong …

Duke’s Anil Potti resigns

Duke University photo

Duke’s Anil Potti, the Duke cancer researcher who falsely claimed to be a Rhodes Scholar and may have faked several analyses of chemotherapy and cancer, has resigned from the university.

The Duke Chronicle reports that Potti

…stepped down from his position at Duke’s Institute for Genome Sciences and Policy Friday and took responsibility for the problems in his research, IGSP Director Huntington Willard wrote in an e-mail to IGSP staff.

Willard wrote that Potti “accepted full responsibility for a series of anomalies in data handling, analysis and management that have come under scrutiny in the past months.”

He said that investigations into Potti’s research will continue, as will IGSP’s examinations of Potti’s science.

The resignation follows the retraction earlier this week of one paper Potti co-authored in the Journal of Clinical Oncology.

We’ll update as we learn more.

Please see an update about a second paper now being retracted by one of Potti’s co-authors.

JCO makes it official, retracting paper co-authored by Anil Potti

We have a follow-up to our post two weeks ago about a possible retraction in the case of Anil Potti, the Duke cancer researcher who falsely claimed to be a Rhodes Scholar and may have also faked an analysis of how breast cancer responds to chemotherapy.

In that post, we noted that the Raleigh News & Observer had reported that one of Potti’s collaborators, Duke’s Joseph Nevins, had requested that a 2007 paper they co-authored be retracted. The journal told us this morning that the retraction went live yesterday. In it, the authors write: Continue reading JCO makes it official, retracting paper co-authored by Anil Potti