High-profile critic slams Nature letters about dinosaur growth following corrections

cover_nature (1)Authors of a pair of letters in Nature that concluded dinosaurs reached their full size surprisingly quickly are standing by their conclusions, despite challenges from a high-profile critic.

In the letters, researchers led by first author Gregory M. Erickson, a paleobiologist at The Florida State University, concluded that massive dinos grew fast — for example, a 5.5 ton T-Rex could reach skeletal maturity in just two decades. However, when Nathan Myhrvold tried to reanalyze the data, he couldn’t replicate the results. The authors have issued corrections to address the small mistakes unearthed by Myhrvold’s analysis, but argue he couldn’t replicate their results because they hadn’t fully explained their methodology.

After Myhrvold attempted to replicate the findings of maximum size and growth rate for several papers, he found issues in many, including the two Nature letters, according to a press release on Myhrvold’s website: Continue reading High-profile critic slams Nature letters about dinosaur growth following corrections

Surgery studies lacked ethics committee approval

3Surgery Today has pulled a pair of papers that share many authors because the studies they describe were not approved by an institutional ethics committee.

One describes a case in which the researchers removed a mass from a 64-year-old woman’s small intestine; the other describes how the authors removed a growth from a patient’s pancreas. They conclude that the surgery techniques used — like a laparoscopic pancreaticoduodenectomy, a take on the “Whipple Procedure” — can be “feasible, safe, and effective” in certain patients.

The papers share several authors, including a first author, Akihiro Cho, whose affiliation on the papers is Chiba Cancer Center Hospital in Japan. They also share a retraction note, which explains how the journal learned of the issue:

Continue reading Surgery studies lacked ethics committee approval

Upon discovering several errors, authors retract gastric cancer paper

mmr_12_4After finding several errors in their paper about the molecular activity underlying gastric cancer, the authors unanimously decided to retract it.

According to the retraction note, three figures in the paper had β‑actin bands that were omitted, interchanged, or both.

The retraction note provides the details:

Continue reading Upon discovering several errors, authors retract gastric cancer paper

Journals flag 6 papers, request investigation of New Jersey university biologists

Two journals have published six expressions of concern for a pair of biologists at Rowan University, and are asking the university to undertake an investigation.

We contacted the editors of the two journals — Journal of Cell Science and Biology Open — who both said they decided to flag the papers after a reader raised concerns about potential re-use of blot images. The six papers are co-authored by John G. Pastorino, a molecular biologist at Rowan University in New Jersey and Nataly Shulga, whose LinkedIn identifies her as a research specialist at the same institution. According to the nearly identical notes, the journals (which share a publisher) undertook a review of the original data, but “felt unable to resolve this matter.”

The expressions of concern — five from the  Journal of Cell Science and one from Biology Open — include pretty much the same text. Here’s the note that appeared in JCS:

Continue reading Journals flag 6 papers, request investigation of New Jersey university biologists

STAP stem cell researcher Obokata loses another paper

Nature protocols

The first author of two high-profile Nature retractions about a technique to easily create stem cells has lost another paper in Nature Protocols.

Haruko Obokata, once “a lab director’s dream,” according to The New Yorker, also had her PhD revoked from Waseda University last fall.

After learning of concerns that two figures are “very similar” and “some of the error bars look unevenly positioned,” the rest of the authors were unable to locate the raw data, according to the note. The journal could not reach Obokata for comment before publishing the retraction.

Reproducible subcutaneous transplantation of cell sheets into recipient mice” has been cited 21 times, according to Thomson Reuters Web of Science. It was published in June 2011, soon after Obokata earned her PhD. 

Here’s the note:

Continue reading STAP stem cell researcher Obokata loses another paper

Top journals give mixed response to learning published trials didn’t proceed as planned

Ben Goldacre
Ben Goldacre

Ben Goldacre has been a busy man. In the last six weeks, the author and medical doctor’s Compare Project has evaluated 67 clinical trials published in the top five medical journals, looking for any “switched outcomes,” meaning the authors didn’t report something they said they would, or included additional outcomes in the published paper, with no explanation for the change. The vast majority – 58 – included such discrepancies. Goldacre talked to us about how journals – New England Journal of Medicine (NEJM), JAMA, The Lancet, BMJ, and Annals of Internal Medicine — have responded to this feedback.

Retraction Watch: When you discover a published trial has switched outcomes, what do you do? Continue reading Top journals give mixed response to learning published trials didn’t proceed as planned

Cyberterrorism paper under attack for plagiarizing from multiple sources

2012032903645393A paper about combating cyberterrorism is coming under fire after allegations of plagiarism sparked on social media.

Soon after the paper was published by the journal Computer Technology and Application in 2015, Orgnet LLC, a network analysis software company, announced on Twitter that the paper took content from its webpage. The firm tweeted: Continue reading Cyberterrorism paper under attack for plagiarizing from multiple sources

Methodology of paper linking vaccine to behavioral issues “seriously flawed,” says retraction

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After temporarily removing a paper that suggested a link between the vaccine for the human papillomavirus (HPV) and behavioral issues, the journal has now retracted it.

Vaccine says the reason is “serious concerns regarding the scientific soundness of the article,” including flawed methodology and unjustified claims.

Christopher A. Shaw, a co-author on the paper and a researcher at the University of British Columbia, told us he has seen the notice, but doesn’t know the specific issues the journal had with the paper:

We still don’t know why [Editor in Chief] Dr Poland removed the article.

Here’s the retraction notice for “Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil:”

Continue reading Methodology of paper linking vaccine to behavioral issues “seriously flawed,” says retraction

Doctor suspended in UK after faking co-authors, data

Screen Shot 2016-02-24 at 11.04.56 AMA doctor in Manchester, UK has received a year’s suspension by the Medical Practitioners Tribunal Service.

Gemina Doolub admitted that she fabricated research data and submitted papers without the knowledge of her co-authors, including faking an email address for a co-author, a news story in the BMJ reports. The research in question was part of two retractions that Doolub received in 2013, one of which we covered at the time.

Doolub’s research examined ways to treat and avoid microvascular obstruction — that is, blocked arteries. Doolub did the work while at Oxford.

Intracoronary Adenosine versus Intravenous Adenosine during Primary PCI for ST-Elevation Myocardial Infarction: Which One Offers Better Outcomes in terms of Microvascular Obstruction?” was published in International Scholarly Research Notices Cardiology and has not yet been cited, according to Thomson Reuters Web of Science.

As the BMJ reports, in that paper,

Continue reading Doctor suspended in UK after faking co-authors, data

Don’t trust an image in a scientific paper? Manipulation detective’s company wants to help.

Mike Rossner. Source: S. Peterson
Mike Rossner. Source: S. Peterson

Mike Rossner has made a name for himself in academic publishing as somewhat of a “manipulation detective.” As the editor of The Journal of Cell Biology, in 2002 he initiated a policy of screening all images in accepted manuscripts, causing the journal to reject roughly 1% of papers that had already passed peer review. Other journals now screen images, but finding manipulation is only the first step – handling it responsibly is another matter. Rossner has started his own company to help journals and institutions manage this tricky process. We talked to him about his new venture.

Retraction Watch: What are the primary services offered by your company?

Continue reading Don’t trust an image in a scientific paper? Manipulation detective’s company wants to help.