Category: elsevier

Journal retracts antipsychotic study when all subjects’ PET scans turn out to be unreliable or invalid

The Journal of Psychiatric Research is retracting a 2010 paper claiming to show a relationship between quetiapine (Seroquel) and certain lab tests and brain scans, after it turns out the brain images were either unreliable or invalid.

Here’s the notice for “Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine”: Continue reading Journal retracts antipsychotic study when all subjects’ PET scans turn out to be unreliable or invalid

Controversial paper on life-extending buckyballs corrected after blog readers note problems

Back in April, a group of French and Tunisian researchers published a paper in Biomaterials which came to the astonishing conclusion that buckyballs (carbon tetrachloride) coated in olive oil could dramatically extend the lives of lab rodents. That news was picked up by Derek Lowe’s In the Pipeline blog, on which he expressed some bemusement about the work but ultimately praised it:

These are reasonable (but unproven) hypotheses, and I very much look forward to seeing this work followed up to see some more light shed on them. The whole life-extension result needs to be confirmed as well, and in other species. I congratulate the authors of this work, though, for giving me the most number of raised eyebrows I’ve had while reading a scientific paper in quite some time.

One of those eyebrows dropped a bit the following day, when Lowe reported that readers had pointed him to a clear case of image duplication in the article. At the time, Lowe concluded: Continue reading Controversial paper on life-extending buckyballs corrected after blog readers note problems

Following investigation, Erasmus social psychology professor retracts two studies, resigns

Dirk Smeesters

The social psychology community, already rocked last year by the Diederik Stapel scandal, now has another set of allegations to dissect. Dirk Smeesters, a professor of consumer behavior and society at the Rotterdam School of Management, part of Erasmus University, has resigned amid serious questions about his work.

According to an Erasmus press release, a scientific integrity committee found that the results in two of Smeesters’ papers were statistically highly unlikely. Smeesters could not produce the raw data behind the findings, and told the committee that he cherry-picked the data to produce a statistically significant result. Those two papers are being retracted, and the university accepted Smeesters’ resignation on June 21.

The release also takes pains to say that the university has no reason to doubt the work of his co-authors. You can read the complete report in Dutch, with Smeesters’ co-authors’ names blacked out, in an NRC Handelsblad story.

Erasmus tells Retraction Watch that these are the two papers being retracted: Continue reading Following investigation, Erasmus social psychology professor retracts two studies, resigns

Biologists delete paper from literature after realizing they’d deleted too many genes

Researchers deleted more genes than they bargained for in a Drosophila strain, a mistake that resulted in a retraction of a paper from 2007.

Ron Wides, a biologist specializing in pattern development at Bar-Ilan University, Israel, and colleagues have retracted a paper published in Mechanisms of Development after his lab found that their technique to delete the Ten-a gene ended up deleting other nearby genes, too.

It was deletions of other genes, and not Ten-a, that killed the fruit flies, Wides concluded. His group had also concluded, erroneously, that Ten-a is what’s known as a “pair-rule” gene. Fruit fly embryos develop in stacked segments, like tubes of Pringles; pair-rule genes guide the development of alternating segments. Those other loci, and not Ten-a, caused lethality and caused the flies to develop improperly early,  Wides concluded.

The retraction reads in full: Continue reading Biologists delete paper from literature after realizing they’d deleted too many genes

‘Molecular characterization’ errors lead to retraction from medicinal chemistry journal

The European Journal of Medicinal Chemistry has published a curious retraction notice for a paper in its February 2012 issue from a group of Indian scientists.

The abstract of the article,”Proton-pumping-ATPase-targeted antifungal activity of cinnamaldehyde based sulfonyl tetrazoles,” is still available on Medline:

Here’s what the abstract of the paper said about the study: Continue reading ‘Molecular characterization’ errors lead to retraction from medicinal chemistry journal

Millennium Villages Project forced to correct Lancet paper on foreign aid as leader leaves team

A senior member of a high-profile foreign aid research team has left the project on the heels of a Lancet correction of a heavily criticized paper the team published earlier this month.

Paul Pronyk, who until last week was director of monitoring and evaluation at Columbia University’s Center for Global Health and Economic Development, which runs the Millennium Villages Project, wrote a letter to the Lancet acknowledging errors in the paper, “The effect of an integrated multisector model for achieving the Millennium Development Goals and improving child survival in rural sub-Saharan Africa: a non-randomised controlled assessment,” originally published May 8. That admission came after Jesse Bump, Michael Clemens, Gabriel Demombynes, and Lawrence Haddad wrote a letter criticizing the work, which was published this week accompanied by corrections to the paper: Continue reading Millennium Villages Project forced to correct Lancet paper on foreign aid as leader leaves team

An Immunity retraction for Luk van Parijs, three years after the ORI found evidence of fabrication in the paper

Earlier this month, we reported on a correction by Luk van Parijs, the biologist the Massachusetts Institute of Technology (MIT) fired in 2005 after he admitted to making up data.

Immunity has now run a retraction involving van Parijs, dated May 25, 2012, for 2003’s “Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1”: Continue reading An Immunity retraction for Luk van Parijs, three years after the ORI found evidence of fabrication in the paper

Not for the faint of heart: Cardiologists retract syncope paper after realizing data columns weren’t aligned right

Improperly aligned columns have cost researchers at the Mayo Clinic a paper in the Journal of the American College of Cardiology.

The paper originally concluded that fainting spells (syncope) give patients with high blood pressure in their lung arteries poor prognoses, an observation that turned out to be incorrect.

The problem? The group merged two electronic databases, but did not align columns properly, a problem found only after first author Rachel Le revisited the dataset looking to cull more data.

The retraction notice published on May 22 (the one on ScienceDirect is free to air, while the one on the JACC site is behind a paywall): Continue reading Not for the faint of heart: Cardiologists retract syncope paper after realizing data columns weren’t aligned right

Mighty molten powder researchers publish paper in journal twice, months apart

A group of French researchers liked their paper on the properties of molten tin so much they published it twice. In the same journal. Four months apart.

The article, “Nitrogen spray atomization of molten tin metal: Powder morphology characteristics,” first appeared online in the January 2007 issue of the Journal of Materials Processing Technology. That one has been cited four times, according to Thomson Scientific’s Web of Knowledge.

In May 2007, the same group, sans two authors, published a paper online in the JMPT (and in January 2008 in print) with the identical title. That article — which managed to get cited three times — has now been retracted: Continue reading Mighty molten powder researchers publish paper in journal twice, months apart

Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”

A group of researchers at the University of Utah has retracted two papers from Cell Metabolism after they realized that a dismissed employee had tossed out data that were the basis of some error-laden figures.

Here’s the notice for both papers: Continue reading Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”