Teflon toxicity paper fails to stick

toxicological sciencesAn advanced online paper on prenatal toxicity of perfluorooctanoic acid (PFOA), an industrial chemical used to make waterproof coatings and Teflon, is being retracted due to “some minor errors.”

High blood levels of PFOA have been tied to kidney disease in humans, as well as several cancers in animal models. The majority of the U.S. Environmental Protection Agency’s scientific advisory board deemed PFOA “likely to be carcinogenic in humans” in 2006, though a decade later the EPA has yet to make a decision on regulations. The retracted paper found that exposing pregnant mice to PFOA altered hormone pathways in mammary glands.

According to the notice in Toxicological Sciences, there was a duplicated image in one of the figures, as well as “some minor errors.” Here’s figure 5B: Continue reading Teflon toxicity paper fails to stick

Nature retracts epigenetics paper by author who lost two Science papers last year

cover_natureFrank Sauer, formerly of the University of California, Riverside, has had a 2002 letter on epigenetics retracted from Nature due to “inappropriate image manipulation.”

Sauer had two papers retracted from Science last year following a university investigation. Here’s the Nature notice for “Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1:” Continue reading Nature retracts epigenetics paper by author who lost two Science papers last year

Expression of concern opens floodgates of controversy over lead in water supply

journal-awwa-cover-feb-2015An expression of concern has been published on a paper that taps into a decades-long fight over how to remove lead from the water supply.

The paper in question, published in the Journal American Water Works Association, supports the safety of a common but frequently criticized way of incrementally removing lead pipes. The expression of concern came after years of back-and-forth  letters to the editor between other scientists and the authors.

Lead water pipes have been causing lead poisoning for generations; some people have even theorized that the ancient Romans’ use of the metal facilitated the empire’s downfall. The dangers of childhood exposure to lead — delayed development, irreversible damage to the brain and nervous system and behavioral problems — have been documented in the U.S. since the 1940s, but the Environmental Protection Agency didn’t start regulating lead levels in drinking water until 1991, when the “lead and copper rule” went into effect. That set the standard for utility companies’ lead testing: if 10 percent or more of samples from homes had lead levels above 15 parts per billion, the companies were required to replace 7% of their lead pipes a year until they met the requirements.

Continue reading Expression of concern opens floodgates of controversy over lead in water supply

Lawsuit involving PubPeer unmasks commenter as pseudonymous whistleblower Clare Francis

pubpeerAn attorney for Fazlul Sarkar, the Wayne State University researcher who claims he lost a job offer because of comments about his research on PubPeer, has asked a judge to reconsider last month’s decision not to release information about the site’s anonymous commenters. As a consequence, the brief in support of that motion identifies a key commenter as the pseudonymous Clare Francis.

On March 19, a Michigan court ruled that PubPeer had to disclose identifying information about a single commenter, who left the second of these comments: Continue reading Lawsuit involving PubPeer unmasks commenter as pseudonymous whistleblower Clare Francis

Unhappy medium: Penn State website retracts article touting student psychic

onward stateOnward State, an alternative student news website for Penn State University, has pulled an article about a student psychic for promoting “one of the most fraudulent, predatory practices around.”

The psychic has been given her own reality TV show on ABC Family (an oxymoron if ever there was one). The newspaper had reported the news of the show with, shall we say, something of a credulous eye. Per the item: Continue reading Unhappy medium: Penn State website retracts article touting student psychic

Study by deceased award-winning cancer researcher retracted because some patients were “invented”

cancerA 2002 paper has been retracted by Cancer after some of the authors notified the journal that they hadn’t agreed to submit it — and an investigation found that a number of the patients described had been made up.

Here’s the notice for “Radioimmunotherapy of small-volume disease of metastatic colorectal cancer: results of a phase II trial with the iodine-131–labeled humanized anti–carcinoembryonic antigen antibody hMN-14:” Continue reading Study by deceased award-winning cancer researcher retracted because some patients were “invented”

Stats error has chilling effect on global warming paper

global change biologyIt turns out a 2014 paper that found a surprising pattern of plant migration in response to global warming was not so surprising after all — it’s been retracted by the authors due to a mistake in the statistical analysis.

Most studies on migrating populations have found that species around the globe move north to escape the rising temperatures. But the authors of the 2014 paper in Global Change Biology found the opposite — according to their analysis, many plant species in Western North America had been migrating south, toward warmer climates.

The lead author Melanie Harsch told Science in 2014 that the team had been suspicious of the analysis, and so ran it twice: Continue reading Stats error has chilling effect on global warming paper

Poll: What to do when peer review feels inadequate?

Imagine via Raul Pacheco-Vega
Image via Raul Pacheco-Vega

How should scientists think about papers that have undergone what appears to be a cursory peer review? Perhaps the papers were reviewed in a day — or less — or simply green-lighted by an editor, without an outside look. That’s a question Dorothy Bishop, an Oxford University autism researcher, asked herself when she noticed some troubling trends in four autism journals.

Recently, Bishop sparked a firestorm when she wrote several blog posts arguing that these four autism journals had a serious problem. For instance, she found that Johnny Matson, then-editor of Research in Developmental Disabilities and Research in Autism Spectrum Disorders, had an unusually high rate of citing his own research – 55% of his citations are to his own papers, according to Bishop. Matson also published a lot in his own journals – 10% of the papers published in Research in Autism Spectrum Disorders since Matson took over in 2007 have been his. Matson’s prodigious self-citation in Research in Autism Spectrum Disorders was initially pointed out by autism researcher Michelle Dawson, as noted in Bishop’s original post.

Short peer reviews of a day or less were also common. Matson no longer edits the journals, both published by Elsevier.

Bishop noted similar findings at Developmental Neurorehabilitation and Journal of Developmental and Physical Disabilities, where the editors (and Matson) frequently published in each others’ journals, and they often had short peer reviews: The median time for Matson’s papers in Developmental Neurorehabilitation between 2010 and 2014 was a day, and many were accepted the day they were submitted, says Bishop.

Although this behavior may seem suspect, it wasn’t necessarily against the journals’ editorial policies. This is the peer review policy at RIDD:

Continue reading Poll: What to do when peer review feels inadequate?

Wayne State neuroscientist fudged images in five papers

Teresita L. Briones
Teresita L. Briones

Teresita Briones, a former nursing professor at Wayne State University in Detroit who studied neuroscience, manipulated images in five papers, according to the Office of Research Integrity.

Briones, who focused on neuroplasticity: Continue reading Wayne State neuroscientist fudged images in five papers

Former Columbia postdoc faked Alzheimer’s research in Cell and Nature

cover_natureRyousuke Fujita, a former Columbia University postdoc who admitted to having faked the findings of a 2011 Cell paper in a retraction notice last year, also faked the results of a 2013 Nature paper, according to a new report from the Office of Research Integrity (ORI).

Fujita’s work, in conjunction with Asa Abeliovich, was widely hailed as a significant step forward, a way to turn skin cells into brain cells. But the story began falling apart when the Cell retraction said that he “acknowledged inappropriately manipulating image panels and data points, as well as misrepresenting the number of repeats performed.”

The ORI’s findings in the case also involve a 2013 Nature paper, “Integrative genomics identifies APOE ε4 effectors in Alzheimer’s disease,” and a paper never published. Fujita, according to the ORI: Continue reading Former Columbia postdoc faked Alzheimer’s research in Cell and Nature