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Journal to retract paper called “anti-vaccine pseudoscience”

A journal is planning to retract a paper that purported to link a component of vaccines to autism in mice.

The paper, about the effects of aluminum adjuvants in vaccines on the immune response in the brains of mice, is the second retraction for co-authors Christopher Shaw and Lucija Tomljenovic, of the University of British Columbia. The journal’s editor told us he and the authors are jointly retracting the paper. 

Just over a month old, the paper has already received plenty of criticism. Numerous commenters on PubPeer have allegedly identified image duplications and other problems with the paper. One commenter described “clear and deliberate” removal of control results in the paper, while others suggested gel bands were duplicated within the paper, and appear similar to those from another paper published in 2014 by Shaw and Tomljenovic. In a blog post, David Gorski, a professor and surgeon at Wayne State University, called the paper “antivaccine pseudoscience.”

Shaw, the paper’s last author, told us that his lab became aware of the PubPeer discussion a few weeks after publication:  Continue reading Journal to retract paper called “anti-vaccine pseudoscience”

Society recommends 9 retractions for co-author of researcher with record number of retractions

The Japanese Society of Anesthesiologists (JSA) has requested the retraction of nine additional papers by a co-author of fraudster Yoshitaka Fujii, after investigating allegations of fraud in dozens of papers.

According to the report, a committee investigated approximately 40 publications by Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University and “identified ten publications with clear ethics violations, one of which has already been retracted.”

Saitoh has collaborated on many papers with Fujii, an anesthesia researcher with more than 180 retractions. As we reported, Saitoh resigned from the JSA when the investigation began, and the society permanently banned him. Continue reading Society recommends 9 retractions for co-author of researcher with record number of retractions

Case report of stem cell therapy in child didn’t meet “ethical standards,” says journal

A journal has retracted a recent case report about a stem cell therapy in a child with cerebral palsy, after discovering the study failed to meet “ethical standards.”

According to the journal, Regenerative Medicine, the ethical issue is that the authors failed to report the case to the Ministry of Health, Labor and Welfare of Japan, which violates the country’s guidelines for conducting stem cell research. Unfortunately, we don’t know much more than that about what happened.

Laura Dormer, editorial director of Future Science Group, which publishes Regenerative Medicine, explained that the paper’s first author, Masato Kantake, requested the retraction because: Continue reading Case report of stem cell therapy in child didn’t meet “ethical standards,” says journal

What types of researchers are most likely to recycle text? The answers might surprise you

Willem Halffman
Serge Horbach

Historians, economists, biochemists, psychologists: Who reuses their own material most often? Does the rate depend on how many authors a paper has, and how far along a researcher is in his or her career? Serge Horbach and Willem Halffman at Radboud University Nijmegen in the Netherlands tried to answer these questions by reviewing more than 900 papers published by researchers based in The Netherlands. And they were surprised by their findings, published last month by Research Policy.

Retraction Watch: How does the amount of text recycling you identified among researchers at Dutch universities (6.1%) compare to what other studies have shown among other groups of researchers?

Continue reading What types of researchers are most likely to recycle text? The answers might surprise you

Early data on potential anti-cancer compound now in human trials was falsified, company admits

A pharmaceutical company has admitted that one of its former researchers falsified early data on a compound that’s designed to fight cancer, now in human trials.

The data, published as an abstract in August 2015 in the journal Cancer Research, reported a therapeutic benefit of acalabrutinib in a mouse model of pancreatic cancer. The compound, developed by the company Acerta Pharma, has also been the subject of additional trials published in the New England Journal of Medicine and Blood in 2015. The 2015 NEJM study, which had several authors in common with the Cancer Research abstract, showed the agent had “promising safety and efficacy profiles in patients” with relapsed chronic lymphocytic leukemia.

But an investigation into the data underlying the 2015 abstract shows some were falsified, prompting the journal to retract the abstract.

Ed Tucker, senior vice president of Medical Safety, Quality and Compliance at Acerta Pharma, told us that in August 2016 the company identified an issue with the data in the Cancer Research abstract and started an investigation:

Continue reading Early data on potential anti-cancer compound now in human trials was falsified, company admits

Nature adds alert to heavily debated paper about gene editing

Nature has added an “editor’s note” to a high-profile August paper alerting readers to the fact that the article has been subject to criticism.

Journals often flag papers that are being debated — what’s unusual here is that the journal doesn’t label the notice as an official “Expression of Concern,” which are indexed by PubMed. Yet the Nature notice reads just like an expression of concern.

Here’s the text of the new notice, which was added October 2 (and spotted by Paul Knoepfler):

Continue reading Nature adds alert to heavily debated paper about gene editing

Second retraction for psychologist reveals clues about culprit behind misconduct

A social psychologist has retracted a second paper that contains “fabricated or manipulated data.”

The first retraction for William Hart at the University of Alabama — also due to data manipulation — appeared earlier this year. The notice raised some questions over authorship: Hart was the sole author, but he blamed the retraction on a graduate student who supplied the problematic data. The questions continued when Hart’s colleagues posted blogs about the problems that occurred in Hart’s lab, using a pseudonym to describe the student, who apparently admitted to fabricating data.  

The author of one of those blogs, Hart’s colleague Alexa Tullett, told us in March that she was retracting another paper she wrote with Hart and the unnamed graduate student. Recently, she confirmed this latest retraction is that paper.

Looking at the author list of the newest retraction, by process of elimination, we now have a lead on the identity of the graduate student who allegedly took responsibility for the misconduct.

Tullett told us:

Continue reading Second retraction for psychologist reveals clues about culprit behind misconduct

Co-author of now-retracted paper about video games apparently demoted to “lecturer” by uni

Jodi Whitaker, via University of Arizona

A researcher who co-authored a paper about violent video games that was retracted earlier this year appears to have changed positions, according to her website.

After her PhD was revoked by The Ohio State in August, Jodi Whitaker’s listed position at the University of Arizona changed from “assistant professor” to “lecturer.” The page also has removed the information about her PhD, and lists her highest degree as a master’s degree in social psychology from the University of Michigan.

Whitaker has also removed the retracted paper — which includes the title “Boom, Headshot!” — from her list of publications.

Continue reading Co-author of now-retracted paper about video games apparently demoted to “lecturer” by uni

Errors in govt database prompt authors to retract and replace paper in JAMA journal

Researchers have retracted and replaced a June 2016 paper in JAMA Internal Medicine after discovering errors in their data.

The paper explored whether Accountable Care Organizations (ACOs) — groups of health care providers who earn more when they deliver high-quality care without boosting costs  — improve care and lower health care costs for Medicare patients. The paper’s corresponding author, Carrie H. Colla, and her colleagues examined Medicare data over five years and found the ACOs provided “ modest savings on average”  and less hospital care.  

But the data from the Centers for Medicare & Medicaid Services (CMS) contained errors. According to Colla, after the paper was published, CMS “let us know in the fall [2016] that there were errors in the files, but weren’t able to give us final replacement files until winter.” Continue reading Errors in govt database prompt authors to retract and replace paper in JAMA journal

ORI finds misconduct in case of biologist paid $100K by university to leave

A biologist who studied the impact of diabetes on the eye inappropriately altered data in five images from three papers, according to a new finding of misconduct issued by the U.S. Office of Research Integrity (ORI).

Readers may be familiar with the subject of the findings: Azza El-Remessy, a former tenured associate professor at the University of Georgia (UGA) in Athens, spoke to us earlier this year about her battle with UGA. In June 2016, UGA found her guilty of research misconduct and recommended she be terminated. El-Remessy fought back, hiring a lawyer to contest the findings, and the university ultimately paid her $100,000 to leave. (For more, here’s UGA’s June 2016 investigation report and the settlement agreement between UGA and El-Remessy.) Continue reading ORI finds misconduct in case of biologist paid $100K by university to leave