Data highjinx forces retraction of tumor paper in JBC

jbccover414The Journal of Biological Chemistry has an illuminating retraction notice — we’re happy to be able to say — about a 2001 article from a group of researchers at the National University of Singapore.

The paper, “Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells,” was written by Jayshree L. Hirpara, Marie-Véronique Clément and Shazib Pervaiz.

It has has been cited 110 times, according to Thomson Scientific’s Web of Knowledge. According to the retraction notice: Continue reading Data highjinx forces retraction of tumor paper in JBC

Expression of Concern tarnishes copper oxide paper

jmcacoverArticles, like lawn furniture, aren’t supposed to rust after just two months. But the Journal of Materials Chemistry A has issued an Expression of Concern for a February 2014 paper by a group of chemists from India over possible problems with several figures in the article.

The paper, “Hierarchically macro/mesostructured porous copper oxide: Facile synthesis, Characterization, Catalytic performance and Electrochemical study of mesoporous copper oxide monoliths,” was written by Gowhar Ahmad Naikoo, of the department of chemistry at Dr. Hari Singh Gour Central University, in Sagar, and two colleagues. It purported to find that:

Continue reading Expression of Concern tarnishes copper oxide paper

Integrity of data “undisputed” in paper pulled for plagiarism

ijpharI shot the sheriff
But I didn’t shoot no deputy, oh no! Oh!
I shot the sheriff
But I didn’t shoot no deputy, ooh, ooh, oo-ooh.

—Bob Marley

A group of pharmacologists in Japan has retracted their 2012 article in the International Journal of Pharmaceutics for plagiarism. But not, they note, for any other reason.

The article, “Suppression of efflux transporters in the intestines of endotoxin-treated rats,” came from researchers in the Department of Drug Absorption and Pharmacokinetics in the School of Pharmacy at Tokyo University of Pharmacy and Life Sciences. It has been cited once, according to Thomson Scientific’s Web of Knowledge.

Continue reading Integrity of data “undisputed” in paper pulled for plagiarism

Multiple data errors force retraction of paper about preemies

adcfnA group of neonatal researchers in Caen has lost their 2013 review article in Archives of Disease in Childhood Fetal & Neonatal Edition for a variety of problems with their analysis of the data.

The article was titled “NIDCAP in preterm infants and the neurodevelopmental effect in the first 2 years,” and its first author was Laura Fazilleau of University Hospital Côte de Nacre.

According to the abstract: Continue reading Multiple data errors force retraction of paper about preemies

NIH/Harvard team loses aging study to manipulated data

agecoverAge has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.

The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.

As the abstract explained: Continue reading NIH/Harvard team loses aging study to manipulated data

How common is scientific misconduct in Nigeria?

nigeriaWe’ve only covered one retraction from Nigeria. But as we’ve often noted, retraction rates don’t necessarily correlate with rates of problematic research, so the low number doesn’t really answer the question in this post’s title.

Lucky for us, a group of authors have started publishing surveys of Nigerian scientists on the subject. In a new such survey published in BMC Medical Ethics, Patrick I. Okonta and Theresa Rossouw asked 150 researchers to fill out a questionnaire during a scientific conference in 2010. Most of them — 133 — complied. Their findings? Continue reading How common is scientific misconduct in Nigeria?

Anonymous blog comment suggests lack of confidentiality in peer review — and plays role in a new paper

neuronA new paper in Intelligence is offering some, well, intel into the peer review process at one prestigious neuroscience journal.

The new paper is about another paper, a December 2012 study, “Fractionating Human Intelligence,” published in Neuron by Adam Hampshire and colleagues in December 2012. The Neuron study has been cited 16 times, according to Thomson Scientific’s Web of Knowledge.

Richard Haier and colleagues write in Intelligence that Continue reading Anonymous blog comment suggests lack of confidentiality in peer review — and plays role in a new paper

Nature corrects a correction

nature 4 9 14Last year, we reported on a Nature correction of a paper for what a McGill University committee had earlier called “intentionally contrived and falsified” figures. It turns out that the correction — like the original paper — left some Nature readers puzzled, so the journal has run a correction of the correction: Continue reading Nature corrects a correction

“[W]e did not succeed:” Frontiers editor on handling of controversial retraction

frontiersControversy continues to swirl around the retraction of a Frontiers paper linking climate skepticism to conspiratorial ideation, with three editors resigning from various Frontiers journals, and competing narratives. The authors say the journal retracted the paper because of a fear of legal threats, while the journal, and critics of the study, has said it was withdrawn because the paper did not protect the rights of its subjects.

Whatever the issues with the paper, we and others have been saying that the journal stumbled since the study was first retracted last year. The publisher continues to insist, for example, that there is no contradiction between their retraction notice — agreed upon by the editors and the authors — which said that the journal “did not identify any issues with the academic and ethical aspects of the study” and a later statement saying that the paper “did not sufficiently protect the rights of the studied subjects.”

Today, editor-in-chief Henry Markham acknowledged missteps in a blog post. Here’s how it starts:

Continue reading “[W]e did not succeed:” Frontiers editor on handling of controversial retraction

Fraud fells Alzheimer’s “made to order” neurons paper in Cell

cell414In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

Continue reading Fraud fells Alzheimer’s “made to order” neurons paper in Cell