De-coli: Plagiarism leads to retraction of highly cited recombinant protein paper

appliedmicrobioThe authors of a 2005 article on E. coli in Applied Microbiology and Biotechnology have lost the paper because they recombined it from previous work.

The article, titled “Strategies for efficient production of heterologous proteins in Escherichia coli,” came from a pair of biochemical engineers from the Indian Institute of Technology-Delhi, in New Delhi, India.

According to the abstract: Continue reading De-coli: Plagiarism leads to retraction of highly cited recombinant protein paper

Braggadacio, information control, and fear: Life inside a Brigham stem cell lab under investigation

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Piero Anversa

The following post was written by a former research fellow in the lab of Piero Anversa to whom we’ve promised confidentiality. Anversa has previously told us that he cannot comment because of an ongoing investigation.

Regular readers of Retraction Watch will note the recent news regarding the work conducted in the laboratory of Piero Anversa at Brigham and Women’s Hospital, a Harvard Medical School affiliate. In the early 2000s, his laboratory published a series of papers regarding the regenerative qualities of bone marrow-derived and cardiac-resident “stem cells.”

Those initial findings, as well as the research conducted since those early studies, have always been surrounded by controversy, as many have been unsuccessful in efforts to replicate their results. Controversy among competitors is not uncommon in our profession, but this particular one has blossomed into a formal investigation of their findings, and has, to date, led to the retraction of one paper and an expression of concern about another. Continue reading Braggadacio, information control, and fear: Life inside a Brigham stem cell lab under investigation

“Misrepresentation,” “reckless disregard for basic scientific standards”: Hauser report reveals details of misconduct

Harvard-logo_7Courtesy of a Freedom of Information Act request, The Boston Globe has a very good piece detailing what investigators found had actually happened in the Marc Hauser lab before the former Harvard psychology researcher resigned in 2011 and was found guilty of misconduct by the Office of Research Integrity (ORI) in 2012.

The Globe requested the 2010 report Harvard sent the ORI. Here’s a summary:

The 85-page report details instances in which Hauser changed data so that it would show a desired effect. It shows that he more than once rebuffed or downplayed questions and concerns from people in his laboratory about how a result was obtained. The report also describes “a disturbing pattern of misrepresentation of results and shading of truth” and a “reckless disregard for basic scientific standards.”

The Globe quotes key passages from the report: Continue reading “Misrepresentation,” “reckless disregard for basic scientific standards”: Hauser report reveals details of misconduct

Science retracts two papers for image manipulation

science 2014Science has retracted two papers by Frank Sauer, of the University of California, Riverside, after the university found evidence of serious image manipulation.

Here’s the notice, signed by Science editor-in-chief Marcia McNutt: Continue reading Science retracts two papers for image manipulation

Researchers repeat retracted study, republish in same journal sans first author

biol psychWe’ve been following the case of Amine Bahi, a neuroscience researcher in the United Arab Emirates who has managed something unusual in the annals of Retraction Watch: Three different retractions for three completely different reasons. One was for “legal issues,” another was for lack of IRB approval, and the third was for using RNAs from the wrong species.

Now, Bahi’s co-authors have repeated the last of those studies with the right RNAs, and have republished their paper in the same journal, Biological Psychiatry — but without Bahi.

The retraction notice for “Blockade of Protein Phosphatase 2B Activity in the Amygdala Increases Anxiety- and Depression-Like Behaviors in Mice” now includes this final paragraph: Continue reading Researchers repeat retracted study, republish in same journal sans first author

Serial fakery: Researcher found to have committed misconduct at Harvard and Oxford

harvardA former Harvard postdoc who was found guilty of faking data at Oxford as a student did the same thing at Harvard, according to the Office of Research Integrity (ORI).

We first wrote about Helen Freeman in February, when we covered a retraction in Cell Metabolism that said the UK’s Medical Research Council had found that she committed misconduct while working as a student at Oxford. Today, a Federal Register notice from the ORI reports that Freeman faked images in a manuscript submitted to Nature while she was working on federally funded grants at Harvard Medical School and Beth Israel Deaconess Medical Center.

From the ORI’s report: Continue reading Serial fakery: Researcher found to have committed misconduct at Harvard and Oxford

Obokata agrees to retract one of two STAP stem cell papers in Nature: Reports

nature 2-27-14The Kyodo News service has reported that Haruko Obokata has agreed to retract one of the two Nature papers on an easy method of making stem cells.

According to the report: Continue reading Obokata agrees to retract one of two STAP stem cell papers in Nature: Reports

Failure to cite leads to ignoble end for xenon paper, and a correction

anaesthesiaXenon may be an inert gas, but that doesn’t mean papers about the molecule aren’t subject to change.

Indeed, the journal Anaesthesia has retracted a 2010 article about xenon-based anesthesia, and corrected a 2005 article by some of the same researchers, for what appears to be a case of wurst slicing.

The 2005 paper, “Comparison of xenon-based anaesthesia compared with total intravenous anaesthesia in high risk surgical patients,” came from a group at the Department of Anaesthesiology and Intensive Care Medicine at University Hospital Schleswig-Holstein, in Kiel, Germany. It has been cited 10 times, according to Thomson Scientific’s Web of Knowledge.

According to the abstract: Continue reading Failure to cite leads to ignoble end for xenon paper, and a correction

Diabetes researcher who says he will no longer publish now up to five retractions

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Cory Toth, via U Calgary

Cory Toth, the University of Calgary diabetes researcher who told us last month he would stop publishing in science following a string of inappropriate manipulations, has retracted another paper.

Here’s the notice in Brain for “Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy:” Continue reading Diabetes researcher who says he will no longer publish now up to five retractions

Oncology researcher Getzenberg notches seventh retraction

GetzenbergRobert Getzenberg, a former Hopkins and Pitt cancer researcher, has retracted another paper, his seventh.

Here’s the notice for “Highly specific urine-based marker of bladder cancer,” a paper first published in Urology in 2005: Continue reading Oncology researcher Getzenberg notches seventh retraction