Author: Cat Ferguson

Nature paper adds non-reproducibility to its list of woes

Despite taking some serious hits, a 2006 letter in Nature isn’t going anywhere.

Years ago, a university committee determined that two figures in the letter had been falsified. The journal chose to correct the paper, rather than retract it — and then, the next year, published a correction of that correction due to “an error in the production process.” To round it out, in June of last year, Nature published a rebuttal from a separate research group, who had failed to replicate the letter’s results.

Still, the first author told us there are no plans to retract the paper, since the follow up experiments published in the corrections confirmed the paper’s conclusions.

Continue reading Nature paper adds non-reproducibility to its list of woes

Journal editor resigns over firestorm from circumcision article

10-5409-logoCircumcision is a hot topic. So hot, questions about a reviewer’s potential conflict with the author of an article promoting circumcision prompted a journal editor to resign, and one academic to call another a “fanatic.”

It began in August, when Brian Morris, professor emeritus of molecular medicine at the University of Sydney, published a critique of a paper that itself had critiqued the practice of circumcision. But the sole reviewer of Morris’s article was a frequent co-author of his, Aaron Tobian of the Johns Hopkins School of Medicine. In his reference section, Morris listed five papers on which he and Tobian were co-authors.

A tipster forwarded us emails from Eduardo Garin, editor in chief of the journal, saying he had resigned from the journal after it refused to retract the paper, despite the fact that its sole reviewer was a frequent collaborator of the author. However, Garin is still listed as editor in chief on the journal’s site.  

Garin confirmed to us that he resigned after the publisher refused to retract or correct the Morris article; however, Xiu-Xia Song, vice director of the editorial office at Baishideng, told us by email that Garin is still the journal’s editor.

Here are some specifics:

Continue reading Journal editor resigns over firestorm from circumcision article

One in 25 papers contains inappropriately duplicated images, screen finds

Elies Bik
Elies Bik

Elisabeth Bik, a microbiologist at Stanford, has for years been a behind-the-scenes force in scientific integrity, anonymously submitting reports on plagiarism and image duplication to journal editors. Now, she’s ready to come out of the shadows.

With the help of two editors at microbiology journals, she has conducted a massive study looking for image duplication and manipulation in 20,621 published papers. Bik and co-authors Arturo Casadevall and Ferric Fang (a board member of our parent organization) found 782 instances of inappropriate image duplication, including 196 published papers containing “duplicated figures with alteration.” The study is being released as a pre-print on bioArxiv.

An example the paper uses of “duplication with alteration” is this Western blot where a band has been duplicated: Continue reading One in 25 papers contains inappropriately duplicated images, screen finds

Chip slip: Irreproducibility erases computer memory paper

nanoscaleResearchers at the Chinese Academy of Sciences have retracted a paper in Nanoscale about an experimental computer chip after they were unable to recreate their published results.

“We retract this article to avoid misleading readers and intend to undertake further tests to confirm our previous results,” they write in the notice.

The scientists are working on developing a chip that uses resistive random-access memory, which allows a huge amount of information to be stored in a tiny package and accessed quickly while using very little power. A number of companies are working on the technology, but none have successfully commercialized it.

Here’s the notice for “High uniformity and improved nonlinearity by embedding nanocrystals in selector-less resistive random access memory” (free, but requires login): Continue reading Chip slip: Irreproducibility erases computer memory paper

Reporting errors sink chem paper on liquid-liquid equilibrium

Jced_coverA team of chemists at Hunan University and Zhejiang Shuyang Chemical Company in China have retracted a paper from the Journal of Chemical & Engineering Data after “inconsistencies with the literature” led them to discover “errors” in the way the data were reported.

According to the corresponding author Qinbo Wang, in December 2014, Robert Chirico, an associate editor at the journal, contacted Wang with concerns that the paper’s data were an anomaly.

Wang then went through the original notes with the first author, and realized that the data reported in the paper didn’t match the experimental results. The lab then conducted further experiments, and discovered that multiple corrections would be necessary. They were, as Wang told us: Continue reading Reporting errors sink chem paper on liquid-liquid equilibrium

Use of data “without permission,” bad authors list, and hidden funding sink mol bio paper

dna cell biology 2A Chinese researcher has lost a paper after the journal discovered he published others’ research without permission and lied about the grant funding he used for the work.

Yihang Shen published a paper using his PhD research on the molecular biology of fetal rodent livers earlier this year in DNA and Cell Biology. Unfortunately, he didn’t have permission to publish the data. He also omitted the names of people who participated in the research, and listed an incorrect funding source.

The “cited grant,” according to the journal editor, was a grant awarded to Richard Finnell, a UT Austin researcher who often works with Shen’s PhD advisor at Shanghai Jiao Tong University, the well-known geneticist Fanyi Zeng.

Here’s the notice for “Characterization of Hydroxymethylation Patterns in the Promoter of b-globin Clusters in Murine Fetal Livers”: Continue reading Use of data “without permission,” bad authors list, and hidden funding sink mol bio paper

Skeleton crew’s second paper broken over methodology issues; more retractions to appear

Olga Panagiotopoulou, via University of Queensland

Bone researcher Olga Panagiotopoulou of the University of Queensland has lost a second paper over “errors in the validation protocol and data.”

The retracted paper in the Journal of Biomechanics, about primate jaws, was subject to an expression of concern in May 2014 November 2013, one of two Panagiotopoulou’s group issued last year over methodological problems. The other paper was later retracted. According to Panagiotopoulou, there will be two more retractions forthcoming, both in the Journal of Anatomy. 

According John Hutchinson, last author of the other retracted paper, that withdrawal was the result of an investigation at his school, the Royal Veterinary College.

Panagiotopoulou emailed us with an explanation:

Continue reading Skeleton crew’s second paper broken over methodology issues; more retractions to appear

Biology team with two retractions now correcting references to nixed papers

Screen Shot 2015-04-14 at 5.59.20 PMA team of biologists that retracted two papers after being “unable to replicate some of the results obtained by the first author of the paper” has now issued a correction to fix references to the two sunk publications.

The corrected paper is a review in the Journal of Virology — known there as a Gem — which discusses how viruses use the membranes of endoplasmic reticulum (ER) to replicate.

The two retractions were not signed by their first author, Riccardo Bernasconi, who won the STSBC-Roche Diagnostics award for one of the papers in 2012. The correction carries all three authors’ names, including Bernasconi’s (as second author).

Here’s more from the correction for “How Viruses Hijack the ERAD Tuning Machinery”: Continue reading Biology team with two retractions now correcting references to nixed papers

Former postdoc suing lab head for publishing paper he says he wrote, without his name

plos biologyA pharmaceutical researcher is suing his postdoctoral advisor and former business partner, accusing him of publishing a paper in PLoS Biology they wrote together, and removing him as an author.

According to the complaint, Andrew Mallon and John Marshall co-founded a company, Ardane Therapeutic, to commercialize a potential therapy that Mallon discovered for Angelman Sydrome, a developmental disorder characterized by cognitive impairment and autism.

In 2011, the two, along with several other members of Marshall’s lab at Brown University, wrote and submitted a paper to Neuron (listing Mallon as the first author), which was not accepted. Shortly after submission, “Mallon and Marshall had a falling out,” the complaint says — specifically, they “disagreed about how Ardane should be operated and about the required standards of legal and ethical conduct.” Mallon left the lab and founded his own company, Calista Therapeutics.

In 2013, Marshall and his team published a paper in PLoS Biology, “Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome,” that had some passages taken almost verbatim from the Neuron submission, the complaint says, but Mallon was not included as an author. According to the lawsuit:

Continue reading Former postdoc suing lab head for publishing paper he says he wrote, without his name

Cancer team loses two papers for image manipulation

bba_2A team spread across multiple institutions in China and McGill University in Canada has retracted two cancer papers over “inaccurate and inappropriately processed Western Blots.”

Some of the figures were also reused between the two articles, both in Biochimica et Biophysica Acta General Subjects.

The articles both tested the cancer-fighting properties of a derivative of the active compound present in Boswellia serrata gum resin.

Continue reading Cancer team loses two papers for image manipulation