Author: Adam Marcus

Nature yanks controversial genetics paper whose co-author was found dead in lab in 2012

naturecover1113Nature has retracted a controversial 2012 paper by a group from Johns Hopkins University which has been the subject of a protracted public dispute.

The article, “Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK,” came from the lab of Jef Boeke,  a celebrated biochemist. But a former lab member, Daniel Yuan, who was fired by Hopkins in late 2011 after 10 years at the institution, had repeatedly raised questions about the validity of the findings. Those concerns eventually made their way into the Washington Post, prompting this response from the university. Continue reading Nature yanks controversial genetics paper whose co-author was found dead in lab in 2012

“Personal rivalry” leads to retraction of nut-health paper

ejpcHere’s a retraction that leaves us itching to know more:

The authors of a recent paper in the European Journal of Preventive Cardiology on nut intake and the risk of high blood pressure and diabetes have pulled their article from publication for an undisclosed conflict of interest.

Now, you wouldn’t know this unless you were willing to pony up the $32 to read the notice, which is behind a pay wall — something that drives us, well, nuts. But here it is:

Continue reading “Personal rivalry” leads to retraction of nut-health paper

Chopping broccoli: Researchers lose paper on florets after readers raise questions

b&mclWith apologies to Dana Carvey, Bioorganic & Medicinal Chemistry Letters has chopped a 2012 paper on the molecular constituents of broccoli florets after readers evidently were forced to do the job of reviewers and point out fatal flaws in the study.

The article, “Two novel bioactive glucosinolates from Broccoli (Brassica oleracea L. var. italica) florets,” came from a group in South Korea and has yet to be cited, according to Thomson Scientific’s Web of Knowledge. But according to the retraction notice, after publication critics pointed out serious problems with the work. To wit: Continue reading Chopping broccoli: Researchers lose paper on florets after readers raise questions

JBC issues correction for paper by Khachigian, who has had four others retracted

jbc1113The Journal of Biological Chemistry has a fairly gory correction — we’d call it a mega-correction — for a 2010 paper by Levon Khachigian, an Australian researcher whose studies of a new drug for skin cancer recently were halted over concerns about possible misconduct, including image manipulation. As we reported earlier this year, Khachigian has already lost four papers, including one in the JBC — which the journal simply noted had “been withdrawn by the authors.”

The new correction involves the article “c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins,” which Khachigian wrote with Jun Ni and Alla Waldman. The paper has been cited nine times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice: Continue reading JBC issues correction for paper by Khachigian, who has had four others retracted

Retraction for authors of muscle paper who lifted data from their own 18-year-old article

janatFor the second time in a week, we’ve seen a journal retract a paper because it duplicated something in its own archive. Yesterday, it was a case of plagiarism in a plant journal. Today, we find that the Journal of Anatomy has retracted an article it published earlier this year by a group of Slovenian authors who took a page (or several) out of their 1995 article in the same periodical.

The article, “Muscles within muscles: a tensiomyographic and histochemical analysis of the normal human vastus medialis longus and vastus medialis obliquus muscles,” came from researchers in the department of orthopedic surgery at the University Medical Centre in Ljubjana. According to the abstract: Continue reading Retraction for authors of muscle paper who lifted data from their own 18-year-old article

Data artifact claims two fruit fly papers from leading UK group — who offer model response

jcbcoverA team of researchers led by Daniel St. Johnston, director of the Gurdon Institute at Cambridge and a prominent developmental biologist in the UK, has lost a pair of articles after finding that their data were unreliable. But rather than “correct” the record with subsequent papers, they’ve withdrawn the problematic work.

To our mind, this is a poster case of doing the right thing by science. We think the notices — as provided by the authors and reported by the journals — pretty much say it all, so we’ll let them speak for themselves, followed by some details St. Johnston shared with us.

The first article, “LKB1 and AMPK maintain epithelial cell polarity under energetic stress,” appeared in 2007 in the Journal of Cell Biology and has been cited 108 times, according to Thomson Scientific’s Web of Knowledge.

According to the retraction notice:

Continue reading Data artifact claims two fruit fly papers from leading UK group — who offer model response

Retraction for stem cell scientist facing misconduct inquiry

scadcoverHere’s a retraction from Stem Cells and Development that we’re just now getting around to covering. The paper, “Non-viral reprogramming of skeletal myoblasts with valproic acid for pluripotency,” appeared in June 2012 in a preliminary online form and was written by a group at the University of Cincinnati. As the retraction notice states: Continue reading Retraction for stem cell scientist facing misconduct inquiry

Dispute over data rights forces retraction of obesity paper

bmcresnotesA group of researchers in South Africa has lost their 2012 article in BMC Research Notes after one of the author’s institutions evidently pulled rank and sought to claim the data as its own.

The article, “Association of body weight and physical activity with blood pressure in a rural population in the Dikgale village of Limpopo Province in South Africa,” appeared last February. Its first author was Seth Mkhonto, who listed two affiliations, the Human Sciences Research Council, in Pretoria, and the University of the Limpopo.

But the latter institution seems not to have given Mkhonto approval to publish the data — a rather strange state of affairs given the whole “publish or perish” ethos of academia.

According to the retraction notice: Continue reading Dispute over data rights forces retraction of obesity paper

Sensing a pattern? Pattern Recognition Letters misses rampant plagiarism in modeling paper

prlcoverIt really isn’t fair to pick on Pattern Recognition Letters, but, well, if the shoe fits…

We had fun at the expense of the journal the last time we found that a duplicate publication had escaped the editors. This time, plagiarism is to blame.

A group of authors from the Institute of Automation at the Chinese Academy of Sciences published, then promptly lost, their September 2013 article in PRL titled “Model-based 3D tracking of an articulated hand from single depth images.”

The abstract: Continue reading Sensing a pattern? Pattern Recognition Letters misses rampant plagiarism in modeling paper

Fernández genetics paper in limbo over data concerns

annrevgenAriel Fernández, the protein researcher whose theories of drug design lately have come in for questioning, has lost a paper, at least for the moment.

The article, “Supramolecular Evolution of Protein Organization,” appeared online in Annual Reviews of Genetics prior to print. It lists Fernández’s affiliation as ProWD Sciences, in Madison, Wisc. Not much exists on the web about that company, however, except an under-construction site. (ProWD, by the way, is short for PROtein-Water-Dehydron, Fernández’s area of interest.)

Here’s the notice: Continue reading Fernández genetics paper in limbo over data concerns