Month: November 2010

JCO makes it official, retracting paper co-authored by Anil Potti

We have a follow-up to our post two weeks ago about a possible retraction in the case of Anil Potti, the Duke cancer researcher who falsely claimed to be a Rhodes Scholar and may have also faked an analysis of how breast cancer responds to chemotherapy.

In that post, we noted that the Raleigh News & Observer had reported that one of Potti’s collaborators, Duke’s Joseph Nevins, had requested that a 2007 paper they co-authored be retracted. The journal told us this morning that the retraction went live yesterday. In it, the authors write: Continue reading JCO makes it official, retracting paper co-authored by Anil Potti

So how many retractions are there every year, anyway?

The title of this post is a question that we’ve been asking ourselves since we started Retraction Watch in August, and that others have asked us since. And we’ve gotten different answers depending where we look:

So the real number is a) probably somewhere between 30 and 95 and b) increasing — which isn’t as precise as we’d like, but is hardly the fault of the various people who’ve tried valiantly to count.

Well, we may be a step closer to precision, sort of. Continue reading So how many retractions are there every year, anyway?

More on the latest Cell retraction: PI says a graduate student was at fault

Carsten Carlberg

This morning we reported on a new retraction in Cell involving fraud from a lab in Finland, which led us to a second retraction of a paper by the same group in the Journal of Molecular Biology. The first author on both papers was Tatjana Degenhardt, who at the time was a graduate student in the lab of Carsten Carlberg, professor of biochemistry at the University of Kuopio.

A few minutes ago Retraction Watch spoke with Carlberg, who had this to say about Degenhardt: Continue reading More on the latest Cell retraction: PI says a graduate student was at fault

Cell retraction for bogus images in genetics paper reveals another, in Journal of Molecular Biology

Call it bad luck, but the journal Cell has been victimized again by image manipulation. For the second time this month, the publication has retracted a paper whose authors acknowledged that one of them had played around with the figures.

Published in August 2009, the paper, “Population-Level Transcription Cycles Derive from Stochastic Timing of Single-Cell Transcription,” has been cited 16 times, according to Thomson Scientific’s Web of Knowledge. It purported to show using computer modeling that

transcriptional cycling, i.e., periodic assembly of transcription factors and their cofactors and the resulting cyclical accumulation of mRNA, may stem from stochastic timing and sequential activation of transcription in individual cells.

The authors, from several European institutions, presented experimental data to back up their computer model, including multiple figures. Some of those, they now admit, were fabricated — to the point where the whole paper collapsed: Continue reading Cell retraction for bogus images in genetics paper reveals another, in Journal of Molecular Biology

Science plays two — a retraction, and concern issued about genetics papers

It’s a busy week at Science. The journal is retracting a controversial paper about which it had previously expressed doubts, and has published an “Expression of Concern” about another article that looks like it might be headed for the same fate.

First, the retraction.

The move involves an October 2009 paper, on which we’ve previously posted, by European researchers who claimed to have made a major advance in the ability to watch how enzymes behave in cells — thereby giving scientists a new tool for monitoring the function of genes.

But back in December, Science editor Bruce Alberts issued this “Expression of Concern” about the research: Continue reading Science plays two — a retraction, and concern issued about genetics papers

It’s poll time: Should a retraction during graduate school mean losing your PhD?

photo by secretlondon123 via flickr http://www.flickr.com/photos/secretlondon/

A few weeks ago, we reported on the case of Emily Horvath, a promising scientist at Indiana University who admitted to falsifying data to make her results look better. Some of that data went into her PhD thesis. That prompted a Retraction Watch reader to ask whether scientists who commit such fraud should be stripped of their PhDs. We figured that was a good poll question, so let us know what you think.

[polldaddy poll=”4062997″]

More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Yesterday,we posted on the retraction of a 2004 Nature paper on innate immunity whose findings had been questioned by two groups. A few hours after we posted that item, we heard back from the senior author of one of the papers doubting that data, Tom DeCoursey. DeCoursey makes a number of important points, so we thought it would be a good idea to share them as a post: Continue reading More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Previously questioned Nature paper on innate immunity retracted

courtesy Nature

Last week, we noted a Nature editorial in which the journal came clean about its higher-than-average number of retractions this year — four. What we missed was the fact that the fourth retraction of the year also appeared in last week’s issue.

The retraction, of a paper called “The large-conductance Ca2+-activated K+ channel is essential for innate immunity,” reads (link to the author’s homepage added): Continue reading Previously questioned Nature paper on innate immunity retracted

Cell pulls fruit fly article, citing image manipulation

The journal Cell has retracted a paper on fruit fly genetics over concerns that the first author, a postdoc in a German laboratory, might have manipulated dozens of electron micrographs in the manuscript.

The article, published in November 2009, was titled “Assembly of Endogenous oskar mRNA Particles for Motor-Dependent Transport in the Drosophila Oocyte.” It has been cited six times since then, according to the Thomson Scientific Web of Knowledge.

Not having the foggiest notion of what those words might mean, other than that the paper was about fruit flies, we called in a ringer, Jeff Perkel, who explained as patiently as he could that the gist of the research involved Continue reading Cell pulls fruit fly article, citing image manipulation

Nature comes clean about retractions and why they’re on the rise

courtesy Nature

This week’s Nature includes a refreshing and soul-searching editorial about retractions. Excerpt (we added links and corrected a misspelling and wrong country in the editorial after a reader noted the errors below):

This year, Nature has published four retractions, an unusually large number. In 2009 we published one. Throughout the past decade, we have averaged about two per year, compared with about one per year in the 1990s, excluding the pulse of retractions of papers co-authored by [Austrian German physicist Jan Hendrick Hendrik Schön].

Given that Nature publishes about 800 papers a year, the total is not particularly alarming, especially because only some of the retractions are due to proven misconduct. A few of the Nature research journals have also had to retract papers in recent years, but the combined data do no more than hint at a trend. A broader survey revealed even smaller proportions: in 2009, Times Higher Education commissioned a survey by Thomson Reuters that counted 95 retractions among 1.4 million papers published in 2008. But the same survey showed that, since 1990 — during which time the number of published papers doubled — the proportion of retractions increased tenfold (see http://go.nature.com/vphd17).

The editorial highlights Continue reading Nature comes clean about retractions and why they’re on the rise