Archive for the ‘cell biology’ Category
The correction replaces an expression of concern on the Journal of the American Chemical Society (JACS) paper, which followed allegations of data manipulation. It provides some un-cropped images, and removes a co-author from the paper. However, it does not appear to address previous allegations of misconduct, nor a recent ruling from an investigation at Hong Kong University (HKU), which found that some of the data were “invalid.”
A former researcher at the University of Michigan and the University of Chicago faked dozens of experiments and images over the course of six years, according to a new finding from the Office of Research Integrity (ORI).
Ricky Malhotra, who studied heart cells, admitted to committing misconduct at both institutions, the ORI said in its report of the case. The fakery involved three National Institutes of Health (NIH) grant applications, one NIH progress report, one paper, seven presentations, and one image file. Despite an investigation at the University of Michigan, where Malhotra was from 2005-2006, he continued this falsification at [University of Chicago], after the [University of Michigan] research misconduct investigation was completed,” according to the ORI. The agency found that he Read the rest of this entry »
The problems came to light after the authors couldn’t reproduce the findings, about a mechanism underlying meiosis. When questioned about the matter, the first author of the paper, Saurav Malhotra, admitted to doctoring data and materials.
A researcher has agreed to a five-year ban on Federal U.S. funding for research after the Office of Research Integrity (ORI) determined that he had falsified or fabricated more than 40 images in nine papers.
The findings, released by the ORI today, are another chapter in a case involving John Pastorino, a cell biologist at Rowan University. In February, we reported that two journals had issued expressions of concern (EOCs) for six of his papers.
Pastorino, according to the ORI, Read the rest of this entry »
A former postdoc at the University of Pittsburgh has admitted to committing research misconduct in published papers and in National Institutes of Health (NIH) grant applications.
One Friday in January, graduate student Meredyth Forbes was reviewing material for her dissertation with her mentor when she decided to make a confession.
She “burst out with a statement that some of the data was fabricated,” said Edward Burns, research integrity officer at the Albert Einstein College of Medicine, where Forbes worked. It was, Burns told Retraction Watch: Read the rest of this entry »
The author of a paper “under editorial review” at the Journal of the American Chemical Society has told us the results the paper have been replicated, contrary to claims made by a former member of her lab.
What’s more, the author said she has submitted a correction to the paper, which is currently flagged with an expression of concern, to provide uncropped images.
We originally reported on the case in February from the perspective of Roger Wong, a former chemist at Hong Kong University who said he hasn’t been able to replicate the findings out of the lab of Dan Yang, a current chemistry professor at HKU (who is female, despite the fact that “Dan” is frequently used as a male name in English). We unfortunately failed to reach Yang in February because of an email glitch; once we contacted Yang, she told us she does not believe Wong’s side of the story:
After an investigation found evidence of misconduct, a biologist has issued a third retraction.
Sudarsanareddy Lokireddy — now a research fellow at Harvard Medical School — “admitted falsification,” a Research Integrity Officer at Nanyang Technological University in Singapore told us in December. According to The Scientist, another journal has also published a correction that the authors had requested earlier.
The newly retracted paper is “Myostatin is a novel tumoral factor that induces cancer cachexia,” published in Biochemical Journal and cited 40 times, according to Thomson Reuters Web of Science. Here’s the retraction note:
The retraction note pins the analysis, which led to faulty data, on a “corporate company.” Aside from the companies that sell the kits used for substrates, assays, and detection, there’s only one company mentioned in the paper:
Generation of the mouse model was performed by the Cyagen Company (Guangzhou, China)
However, a representative of Cyagen says it does not offer the type of analysis described by the retraction note.
We contacted the editors of the two journals — Journal of Cell Science and Biology Open — who both said they decided to flag the papers after a reader raised concerns about potential re-use of blot images. The six papers are co-authored by John G. Pastorino, a molecular biologist at Rowan University in New Jersey and Nataly Shulga, whose LinkedIn identifies her as a research specialist at the same institution. According to the nearly identical notes, the journals (which share a publisher) undertook a review of the original data, but “felt unable to resolve this matter.”
The expressions of concern — five from the Journal of Cell Science and one from Biology Open — include pretty much the same text. Here’s the note that appeared in JCS: