Archive for the ‘cell biology’ Category
According to the notice in Molecular Biology of the Cell (MBoC), the contamination occurred by “unknown means” in the senior authors’ laboratory, who told us the mistake was a difficult one to catch. He added that they discovered the problem after other researchers published conflicting results.
He also noted that the contaminated cell lines were not used for experiments in any other papers.
Diabetes has issued two expressions of concern (EOCs) for papers co-authored by leading diabetes researcher Kathrin Maedler, adding to her previous count of one retraction and three corrections.
Both papers were questioned on PubPeer, alongside several others co-authored by Maedler, who is based at the University of Bremen in Germany. As we previously reported, PubPeer comments have led to one retraction for Maedler in the Journal of Biological Chemistry (JBC), and corrections in various other journals.
One of those corrections has now earned an EOC from Diabetes, which also extends to the original paper. Here are the notices, which asks the University of Bremen to investigate further: Read the rest of this entry »
The report flagged eight published papers (and an unpublished one), six of which had already received expressions of concern (EOCs). Nataly Shulga was a co-author on all eight papers. With these two new retractions in Biology Open and Biochimica et Biophysica Acta (BBA) – Bioenergetics, all of the flagged papers have now been retracted.
Here’s the retraction notice for the Biology Open paper, issued July 15:
An erstwhile cell biologist has retracted five papers published in the Journal of Cell Science (JCS), all of which had been flagged in a recent investigation by the U.S. Office of Research Integrity (ORI).
The probe identified eight papers co-authored by Pastorino, six of which had already received expressions of concern (EOC) — including all of the newly retracted JCS papers. Nataly Shulga is a co-author on all eight papers.
Last week, we reported on the first of the expected retractions of the flagged papers in the Journal of Biological Chemistry.
The Journal of Biological Chemistry has retracted a paper that was one of eight flagged in a recent investigation by the Office of Research Integrity (ORI). The investigation — which concluded that a biologist had falsified or fabricated more than 40 images — resulted in a five-year funding ban.
In May, the ORI announced that John Pastorino, an erstwhile cell biologist at Rowan University in New Jersey, falsified and/or fabricated eight of his published papers (and one unpublished one). Nataly Shulga is a co-author on all eight papers. Six of those eight papers had already received expressions of concern (EOC).
Many figures in four papers by a research team in Malaysia contain duplication or manipulation, a university committee has found, calling for multiple retractions.
We learned about issues with three of the papers, including one in Scientific Reports, earlier this week when they were the talk of Twitter. As journals issued expressions of concern, and an expert wondered how the papers passed peer review at all, the first author, a researcher at the University of Malaya (UM), denied allegations of duplication.
UM was alerted to allegations of misconduct in the Scientific Reports paper last Saturday, and according to a statement published today:
Last week, users alleged on Twitter that three papers by the same team included pictures of cells that were copied and pasted. First author Nima Samie, affiliated with University of Malaya in Malaysia, denied the accusations — but both the Malaysian government and now two journals sees cause for further investigation.
Frontiers in Pharmacology published an expression of concern this morning:
It’s all too easy to mix up cell lines, so we see plenty of retractions for that reason — and, according to an expert in the area, many more cases lurk uncorrected in the literature.
The retraction notice for “Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma” in Cell Biology International explains the authors’ perspective on this case:
Twitter is abuzz today over allegations that a recent paper in Scientific Reports contains a blatant example of duplication.
According to the allegations, a group of researchers in Malaysia have used the same four images to represent some 30 cells at different stages of cell death. One researcher has even suggested the allegedly doctored images appear in three different papers.
Is this a manipulated image? See for yourself:
Nearly five months after a graduate student at the Albert Einstein College of Medicine spontaneously confessed to cooking data, the U.S. Office of Research Integrity (ORI) said today that she has agreed to exclude herself from receiving government funding for three years.