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Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘cell biology’ Category

Authors retract PNAS paper questioned on PubPeer after original films can’t be found

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pnas31912PubPeer leads the way again: The authors of a paper about Parkinson’s disease in the Proceedings of the National Academy of Sciences (PNAS) have retracted it, several months after a commenter highlighted the exact issue that led to the article’s demise.

The paper, originally published in September 2013, was called into question by a commenter on PubPeer in July 2014, who identified two of the paper’s figures as duplications: Read the rest of this entry »

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Written by Cat Ferguson

October 23, 2014 at 10:30 am

“This situation left me ashamed and infuriated with myself:” Scientist retracts two papers

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j bacteriologyA Portuguese group has retracted two papers in the Journal of Bacteriology after mislabeled computer files led to the wrong images being used.

And, we’ve learned in a heartfelt email, the first author was devastated.

Here’s the notice for “MtvR Is a Global Small Noncoding Regulatory RNA in Burkholderia cenocepacia”: Read the rest of this entry »

Written by Cat Ferguson

October 17, 2014 at 12:00 pm

Cell line switch sinks PLoS ONE cancer paper

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plosWe’ve written before about how common cell line mix ups are in cancer research; according to a 2012 Wall Street Journal article (paywalled), between a fifth and a third of cancer cell lines tested by suspicious researchers turned out to be misidentified.

Obviously, mistakenly studying the wrong kind of cancer is a waste of precious resources, both time and money. And it’s clear the problem hasn’t gone away. PLoS ONE just retracted a cancer paper originally published in December 2012 for studying two cell lines that had been contaminated by other cell types.

Here’s the notice for “Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma”:
Read the rest of this entry »

Deceased researcher has two more papers retracted

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free radicalA late researcher in Italy who has already been blamed for image manipulation in a PLOS ONE retraction notice has had two more papers retracted, both from Free Radical Biology and Medicine.

Here’s the notice for 2007’s “Redox regulation of 7-ketocholesterol-induced apoptosis by β-carotene in human macrophages,” by Paola Palozza and colleagues: Read the rest of this entry »

Data questions prompt retraction of PLOS ONE cardiovascular paper

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plosonePLoS One has retracted a 2013 article on atherosclerosis in mice over concerns about the integrity of the data.

The paper, “The Effect of Soluble RAGE on Inhibition of Angiotensin II-Mediated Atherosclerosis in Apolipoprotein E Deficient Mice,” came from a group of researchers in South Korea.

It purported to show that: Read the rest of this entry »

A PNAS expression of concern appears — and so does its revealing backstory

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pnas 1113When retraction notices and expressions of concern appear, particularly those that are opaque, we try our best to find out what’s behind them, whether it’s better explanations or the steps that led to moves. Today, we have one story in which we’ve been able to learn a lot more than usual.

In April, Bas van Steensel, Wendy Bickmore, Thomas Cremer, and Kerstin Bystricky sent a letter to about 80 leading labs in nuclear organization and steroid receptor biology. It began (we’ve added some relevant links): Read the rest of this entry »

Written by Ivan Oransky

September 17, 2014 at 9:30 am

Scientist in Ireland notches two mysterious retractions and a correction

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Sinead Miggin, via NUIM

Sinead Miggin, via NUIM

Sinead Miggin, a biologist at the National University of Ireland Maynooth, has withdrawn two papers from the Journal of Biological Chemistry (JBC) and has corrected another paper, in the Proceedings of the National Academy of Sciences (PNAS).

Here’s the opaque JBC notice for “14-3-3ϵ and 14-3-3σ inhibit Toll-like receptor (TLR)-mediated proinflammatory cytokine induction,” a paper first published in November 2012: Read the rest of this entry »

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