Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘journal of cell science’ Category

Authors correct highly cited biology paper due to “genuine mistake”

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Journal of Cell ScienceAuthors of a highly cited biology paper in the Journal of Cell Science (JCS) have corrected the data underlying one of the figures.

The 2003 paper, “The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors,” has been cited 566 times, according to Thomson Reuters Web of Science. One of the authors is the last author on a recent high profile retraction from Nature Genetics, which cost the first author a grant from the European Molecular Biology Organisation.

The correction note tells us a bit more: Read the rest of this entry »

Journals flag 6 papers, request investigation of New Jersey university biologists

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Two journals have published six expressions of concern for a pair of biologists at Rowan University, and are asking the university to undertake an investigation.

We contacted the editors of the two journals — Journal of Cell Science and Biology Open — who both said they decided to flag the papers after a reader raised concerns about potential re-use of blot images. The six papers are co-authored by John G. Pastorino, a molecular biologist at Rowan University in New Jersey and Nataly Shulga, whose LinkedIn identifies her as a research specialist at the same institution. According to the nearly identical notes, the journals (which share a publisher) undertook a review of the original data, but “felt unable to resolve this matter.”

The expressions of concern — five from the  Journal of Cell Science and one from Biology Open — include pretty much the same text. Here’s the note that appeared in JCS:

Read the rest of this entry »

Investigation of prominent geneticist Latchman finds “procedural matters,” no misconduct

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David Latchman, Birkbeck

An investigation by the University College London has cleared prominent geneticist David Latchman of misconduct, but concluded he has “procedural matters in his lab that required attention.”

Latchman has two retracted paperson PubPeer, there are questions about nearly four dozen more.

The results of the investigation were first reported by the Times Higher Education. We also received a short statement from a UCL spokesperson:

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Sun sets on Sun Yat-sen University cell bio paper

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j cell scienceResearchers at Sun Yat-sen University in China have lost a paper in the Journal of Cell Science for “inappropriate figure manipulations,” which they blame entirely on the first author.

According to the notice, three figures were “inappropriately modified” — cells or nuclei were moved, and the edges of cell images were trimmed. The researchers place the responsibility on first author Liping Chen, claiming that “her co-authors were completely unaware.”

The modifications didn’t affect the conclusions, the note says, but after an investigation by Sun Yat-sen University, the journal decided to retract the paper. Liping Chen says she “regrets the inappropriate figure manipulations,” according to the note.

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Prominent geneticist David Latchman’s group notches second retraction

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j cell scienceA team of researchers whose work is under investigation by University College London has retracted a second paper.

Three of the 11 authors of the 2005 Journal of Cell Science paper being retracted — David Latchman, Richard Knight, and Anastasis Stephanou — were authors of a Journal of Biological Chemistry paper retracted in January. Stephanou takes the blame for the “errors” which felled the Journal of Cell Science paper, about how a tumor suppressor responds to DNA damage.

Here’s the notice for “STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage:” Read the rest of this entry »

University College London mitochondrial biologist resigns after three retractions for image fraud

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Courtesy Nature Publishing Group

A biologist at University College London (UCL) has resigned his post and taken responsibility for “inappropriate figures manipulations” in three now-retracted papers.

Assegid Garedew, formerly a senior research investigator in Salvador Moncada‘s group, stepped down earlier this summer in the midst of an investigation that should be completed soon, Moncada tells Retraction Watch.

The three retraction notices for papers by Garedew and colleagues are all similar.

From Cell Metabolism: “Mitochondrial Dynamics, Biogenesis, and Function Are Coordinated with the Cell Cycle by APC/CCDH1“, cited once, according to Thomson Scientific’s Web of Knowledge: Read the rest of this entry »

Coming clean: A major figure in cardiology publishes a lengthy conflict of interest correction in JAMA

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Authors’ financial disclosures can be a thorny issue for scientific journals.  There’s often confusion over just what should be listed as a conflict of interest, and when relationships are revealed after papers are published, lack of disclosure sometimes leads to corrections.

For example, the Journal of Cell Science recently published this: Read the rest of this entry »

Written by Ivan Oransky

February 7th, 2012 at 4:00 pm

A mega-correction, but no retraction, in the Journal of Cell Science

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In our 2011 year-end post, we promised to keep

…an eye on what may be an emerging trend: The mega-correction. We’ve seen errata notices that correct so many different errors, it’s hard to believe the paper shouldn’t have been retracted. It’s unclear what this means yet, but watch this space for coverage of more examples.

We’ve found another example in the Journal of Cell Science, “Immunobiology of naïve and genetically modified HLA-class-I-knockdown human embryonic stem cells,” originally published in September 2011. The correction begins with what turns out to be a bit of an understatement: Read the rest of this entry »

Written by Ivan Oransky

January 12th, 2012 at 9:30 am

Authors retract Journal of Cell Science study after realizing they were using the wrong gene constructs

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What do you do when it turns out the materials you used in your successful experiment weren’t actually the materials you thought they were?

If you’re Peter Zammit, of King’s College London, and colleagues, you retract a 2008 paper in the Journal of Cell Science. Here’s the notice, for “B-catenin promotes self-renewal of skeletal-muscle satellite cells:” Read the rest of this entry »

Written by Ivan Oransky

January 6th, 2012 at 9:30 am

Third retraction from dismissed Montreal cardiology researcher Zhiguo Wang appears

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Ten days ago, we reported on the dismissal of Zhiguo Wang, a Montreal Heart Institute researcher who had already retracted two papers because of image manipulation. At the time, an official said the institute had requested three more retractions, but when we asked which three papers, we were told:

As written in the press release, the MHI has requested the retraction of three additional scientific articles. We will not be able to confirm the name of the scientific articles and/or publications until confirmation of the retractions.

The first of those three has now appeared, in the Journal of Cell Science, for the 2007 paper, “The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes.” According to the retraction notice — which is unfortunately behind a paywall (see update at end): Read the rest of this entry »