Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘israel retractions’ Category

Retracted paper linking HPV vaccine to behavioral issues republished after revisions

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immunological-researchA retracted study linking the vaccine for human papillomavirus (HPV) to behavioral problems in mice has been republished by a different journal.

The paper has been significantly revised, an author told us, but it still comes the same conclusions. 

In February, the journal Vaccine temporarily removed the study without explanation, and told the authors the editor had asked for further review. Later that month, Vaccine retracted the paper, citing “serious concerns regarding the scientific soundness of the article,” and “seriously flawed” methodology. 

In July, another journal — Immunologic Research — republished the paper. The new version of the paper has been significantly changed, co-author Christopher Shaw from the University of British Columbia (UBC) told Retraction Watch:

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Written by Dalmeet Singh Chawla

October 24th, 2016 at 11:30 am

Physics journal pulls two papers for data shortcuts

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New Journal of PhysicsA publisher is retracting two papers today by a team of physicists who took a short cut in reporting their data.

The papers present a method for imaging very small things — like biological processes on a molecular scale — that could be an alternative to electron microscopy, as the authors explain in a video. But after the papers were published in the New Journal of Physics, last author Ulf Leonhardt, now based at the Weizmann Institute of Science, found out that some of the data

 were pixel-by-pixel mirror-symmetric, which is impossible for genuine experimental data.

One of the researchers co-authored a subsequent paper that acknowledges one of the papers incorrectly assumed the data were symmetrical, and could therefore be extrapolated from one side to the other. A representative of the publisher told us they have not seen any signs of misconduct, and the problem seemed to result from a “series of apparent miscommunications between the authors.”

Here’s the retraction notice for “Evidence for subwavelength imaging with positive refraction:” Read the rest of this entry »

Methodology of paper linking vaccine to behavioral issues “seriously flawed,” says retraction

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After temporarily removing a paper that suggested a link between the vaccine for the human papillomavirus (HPV) and behavioral issues, the journal has now retracted it.

Vaccine says the reason is “serious concerns regarding the scientific soundness of the article,” including flawed methodology and unjustified claims.

Christopher A. Shaw, a co-author on the paper and a researcher at the University of British Columbia, told us he has seen the notice, but doesn’t know the specific issues the journal had with the paper:

We still don’t know why [Editor in Chief] Dr Poland removed the article.

Here’s the retraction notice for “Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil:”

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Written by Shannon Palus

February 25th, 2016 at 10:00 am

Journal temporarily removes paper linking HPV vaccine to behavioral issues

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1-s2.0-S0264410X16X00084-cov150hThe editor in chief of Vaccine has removed a paper suggesting a human papillomavirus (HPV) vaccine can trigger behavioral changes in mice.

The note doesn’t provide any reason for the withdrawal, although authors were told the editor asked for further review.

Two co-authors on the paper — about Gardasil, a vaccine against HPV — have previously suggested that aluminum in vaccines is linked to autism, in research a World Health Organization advisory body concluded was “seriously flawed.”

Approximately 80 million doses of Gardasil were administered in the U.S. between 2006 and 2015. Both the the WHO and the Centers for Disease Control and Prevention have ruled the vaccine to be safe — the CDC, for instance, calls it “safe, effective, and recommended.”

The journal published an uncorrected proof of “Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil” online on January 9th, 2016. In its place now is a note that says:

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Authors retract abstract following misconduct by diabetes biotech

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1Earlier this year, authors retracted a meeting abstract about a diabetes drug, following the revelation that the biotech that funded the trial committed misconduct.

The retraction was initiated by corresponding author Itamar Raz, at Hadassah Medical Center in Israel. The journal didn’t receive a response from any co-authors who were affiliated with the biotech company, Andromeda, so they were not included in the retraction process.

A few months after Hyperion Therapeutics acquired Andromeda’s diabetes drug DiaPep277, Hyperion announced it had evidence that some employees of Andromeda had “engaged in serious misconduct,” such as using un-blinded data and manipulating the analyses. Two relevant studies on the drug, designed to block the immune response that leads to type 1 diabetes, were retracted last year.

Here’s the retraction note for the abstract “Abstracts of the 50th Annual Meeting of the EASD, Vienna 2014. ‘Evaluation of DiaPep277® treatment in type 1 diabetes by integrated analysis,’” published in the May issue of the journal:

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Stem cell researcher Jacob Hanna’s correction count updated to 10

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Jacob Hanna

Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

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A correction to a correction for stem cell researcher Jacob Hanna

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Jacob Hanna

Jacob Hanna

A correction to a correction is the latest problem for highly cited researcher Jacob Hanna. The stem cell scientist — whose high-profile work has received scrutiny over the past year — has amended an earlier correction notice after a reader spotted an inadvertent “mistake.”

We reported on the original correction, to the 2009 Cell Stem Cell paper “Metastable Pluripotent States in NOD-Mouse-Derived ESCs,” in July. The paper has been cited 184 times, according to Thomson Scientific’s Web of Knowledge.

Apparently, a pair of images in the original correction note are of the same cell colonies, when they are supposed to be of separate cell colonies.

The new (and detailed) note explains how that happened:

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Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

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Jacob Hanna

Jacob Hanna

Cell biologist Jacob Hanna, the highly cited stem cell researcher currently at the Weizmann Institute of Science,  has posted a long erratum for a 2005 paper in Blood for “inadvertent mistakes,” among other issues; soon after, Hanna’s team issued another erratum for a 2009 Cell Stem Cell paper.

There’s more to tell: Last month, commenters on PubPeer noticed that images from at least 10 of the research papers Hanna coauthored in seven journals — that commenters had posted on the image hosting website Imgur and linked to on PubPeer — had been deleted.

Imgur did not confirm whether these specific images had been deleted, but told Retraction Watch:

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Duplication of “a major part of text and results” adds up to third retraction for mathematician

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An article by Alexander Spivak, a mathematician based in Israel, is being retracted from the proceedings of a 2014 numerical analysis meeting because Spivak had already published “a major part of text and results” in a mathematics journal in 2010.

Spivak, a member of the faculty of sciences at Holon Institute of Technology, has a bit of a history with the journal that published his initial 201o paper, the International Journal of Pure and Applied Mathematics. That journal retracted two of his papers last year after learning from Zeev Schuss, Spivak’s post-doc supervisor at Tel Aviv University, that those papers contained plagiarized chunks from a paper by Schuss and two colleagues.

Here’s more from the retraction notice for “Successive approximations for optimal control in some nonlinear systems with small parameter”, published in the Proceedings of the 6th International Conference on Numerical Analysis:

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JCI retracts paper by stem cell biologist Jacob Hanna, citing “figure irregularities”

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jciapril2015The Journal of Clinical Investigation has retracted a 2004 paper by Jacob Hanna, a highly cited stem cell researcher in Israel whose work has been dogged by questions about its validity.

Questions about the work, and other articles on which Hanna was an author, were raised on PubPeer last November. This is his first retraction.

The retraction stems from “a number of figure irregularities;” the authors say they were “inadvertently introduced,” and subsequent work has supported their data and conclusions. However, due to the “number of serious mistakes,” the JCI editorial board chose to retract the article. Hanna and corresponding author Ofer Mandelboim at The Lautenberg Center for General and Tumor Immunology — part of Hebrew University, in Jerusalem, where Hanna used to work — say they have accepted the decision.

Hanna, currently at the Weizmann Institute of Science, studies ways to reprogram cells to become more versatile stem cells. He also spent time as a postdoc at the Whitehead Institute in Cambridge and Mount Sinai, in New York City.

Six of Hanna’s papers have been cited more than 500 times, according to Thomson Scientific’s Web of Knowledge. The most-cited, with more than 1,000 citations, was a 2008 Nature paper.

The retracted article, “Novel APC-like properties of human NK cells directly regulate T cell activation,” has been cited 121 times, according to Thomson Scientific’s Web of Knowledge.

The retracted paper examined the early steps of an immune response involving natural killer (NK) cells and antigen-presenting cells (APCs). From the abstract: Read the rest of this entry »