Readers of this blog — and anyone who has been following the Anil Potti saga — know that MD Anderson Cancer Center was the source of initial concerns about the reproducibility of the studies Potti, and his supervisor, Joseph Nevins, were publishing in high profile journals. So the Houston institution has a rep for dealing in issues of data quality. (We can say that with a straight face even though one MD Anderson researcher, Bharat Aggarwal, has threatened to sue us for reporting on an institutional investigation into his work, and several corrections, withdrawals, and Expressions of Concern.)
We think, therefore, that it’s worth paying attention to a new study in PLOS ONE, “A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic,” by a group of MD Anderson researchers. They found that about half of scientists at the prominent cancer hospital report being unable to reproduce data in at least one previously published study. The number approaches 60% for faculty members: Continue reading Half of researchers have reported trouble reproducing published findings: MD Anderson survey