Fraudster’s colleague faked data, too

ori-logoA week after announcing that a researcher formerly at the University of Chicago had faked the results of more than 70 experiments, the U.S. Office of Research Integrity announced yesterday that one of his colleagues also falsified data.

According to the ORI, Karen D’Souza  Continue reading Fraudster’s colleague faked data, too

Heart researcher faked 70+ experiments, 100+ images

ori-logoA former researcher at the University of Michigan and the University of Chicago faked dozens of experiments and images over the course of six years, according to a new finding from the Office of Research Integrity (ORI).

Ricky Malhotra, who studied heart cells, admitted to committing misconduct at both institutions, the ORI said in its report of the case. The fakery involved three National Institutes of Health (NIH) grant applications, one NIH progress report, one paper, seven presentations, and one image file. Despite an investigation at the University of Michigan, where Malhotra was from 2005-2006, he continued this falsification at [University of Chicago], after the [University of Michigan] research misconduct investigation was completed,” according to the ORI. The agency found that he Continue reading Heart researcher faked 70+ experiments, 100+ images

New Jersey university biologist earns funding ban for doctoring more than 40 images

John Pastorino
John Pastorino

A researcher has agreed to a five-year ban on Federal U.S. funding for research after the Office of Research Integrity (ORI) determined that he had falsified or fabricated more than 40 images in nine papers.

The findings, released by the ORI today, are another chapter in a case involving John Pastorino, a cell biologist at Rowan University. In February, we reported that two journals had issued expressions of concern (EOCs) for six of his papers.

Pastorino, according to the ORI,  Continue reading New Jersey university biologist earns funding ban for doctoring more than 40 images

Shigeaki Kato up to 38 retractions

Shigeaki Kato
Shigeaki Kato

Our retraction notice count for Shigeaki Kato, number seven on our leaderboard, has grown to 38.

The former University of Tokyo endocrinologist recently earned another retraction, for a paper in Archives of Biochemistry and Biophysics that contained image manipulation. As we’ve noted before, Kato resigned from the university in 2012 as it investigated his work for misconduct; in 2013 a Japanese newspaper reported that the investigation had found 43 papers from his lab contained “likely altered or forged materials.”

In addition to the new retraction, we’ve dug up four others for Kato from the past few years, plus one correction. Two of the retraction notices mention an investigation at the University of Tokyo.

First, the retraction note for “Multiple co-activator complexes support ligand-induced transactivation function of VDR,” published in December:

Continue reading Shigeaki Kato up to 38 retractions

Following an earlier investigation, GW biologist earns two expressions of concern

3.cover (1)The Journal of Biological Chemistry has flagged two papers by a George Washington University cancer biologist with expressions of concern, following an investigation completed by the university in 2014.

The notes contain little specific information; all we know is that there are questions about the data and conclusions in the papers.

The last author on both papers is Rakesh Kumar, who adds these EoCs to a count that includes, according to our records, three retractions and five corrections. Plus an $8 million lawsuit against his employer for emotional distress when they put him on leave from his position as department chair.

The studies — “Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator” and “Regulation of NF-B circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis” — have been cited 22 times and 33 times respectively, according to Thomson Scientific’s Web of Knowledge.

The expression of concern is the same for both papers — and matches others that we’ve seen from JBC:

Continue reading Following an earlier investigation, GW biologist earns two expressions of concern

Three expressions of concern added to cancer researcher’s notice list

3.coverQuestions about data and conclusions in papers by a cancer researcher at the University of Maryland have led to three expressions of concern in the Journal of Biological Chemistry.

The notices follow four retractions — two for image duplications and two for unknown reasons — for Anil K. Jaiswal. The three papers under notice are all on mechanisms that regulate gene expression; PubPeer commenters have raised questions about some of the figures in the papers.

The expression of concern on all three papers reads, in full:

Continue reading Three expressions of concern added to cancer researcher’s notice list

Singapore investigation leads to two retractions, two more on the way

cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Continue reading Singapore investigation leads to two retractions, two more on the way

Four JBC retractions add up to 8 in total for cancer research pair

47.coverThe Journal of Biological Chemistry is retracting four papers by a pair of cancer researchers at Tulane University, bringing their total to eight.

The retractions are all for reusing parts of figures, either within a paper or from other papers by the pair. Thanks to a new policy at the journal to publish informative notes, we know the figures that were problematic, and the papers that they borrow from. 

An investigation by Tong Wu and Chang Han’s former employer, the University of Pittsburgh, had already led to four retractions for the pair, including two issued this summer.

First up, “Activation of cytosolic phospholipase A2α through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2,” which has been cited 50 times, according to Thomson Scientific’s Web of Knowledge. Here’s the note: Continue reading Four JBC retractions add up to 8 in total for cancer research pair

Now this is good news: In policy change, JBC will now make retraction notices informative

47.coverReaders of this blog know that we have had a few stock villains over the years. High on the list has been the Journal of Biological Chemistry (JBC), and we’ve criticized repeatedly the journal’s unwillingness to provide any information about the reasons for retractions. For as long as we’ve been around, the JBC’s stock retraction statement seemed to be:

This article has been withdrawn by the authors.

Times have changed. According to an editorial published earlier this month, the JBC says it will now be giving readers as much information as possible about the retraction notices it prints. The editorial, written by interim editor-in-chief F. Peter Guengerich of Vanderbilt University, alludes to the heat the journal has been taking about its opacity: Continue reading Now this is good news: In policy change, JBC will now make retraction notices informative

Irish university strips student of PhD following investigation

maynoothMaynooth University has revoked a former student’s PhD following an investigation into the circumstances that led to two previous retractions in the Journal of Biological Chemistry.

During the investigation, Aisha Qasim Butt admitted to some misconduct in the two papers and the research that made up her PhD, according to a university statement (which you can read in full here): Continue reading Irish university strips student of PhD following investigation