Category: expression of concern

Paper by Harvard cancer biologist flagged over “credible concerns”

A cancer biologist at Harvard who’s issued multiple editorial notices in recent years has received an expression of concern about a 2011 paper, citing “credible concerns” with the data and conclusions.

The publisher does not detail the nature of the issues in the notice.

In the past few years, last author Sam W. Lee lost a Molecular Cell paper in 2013 due to figure duplication and a Journal of Biological Chemistry paper in 2015, citing “manipulated” data in a figure.

Lee also issued two mega-corrections in 2011 in Nature and Current Biology, which also cited figure duplication. Interestingly, both papers were corrected for a second time — the 2006 Current Biology paper in 2016, over figure-related errors, and the 2011 Nature paper in 2015, over concerns the animals used may have experienced excess suffering (prompting an editorial from the journal).

The latest notice, issued by the Journal of Biological Chemistry, doesn’t provide much information for the basis of its expression of concern over Lee’s 2011 paper: Continue reading Paper by Harvard cancer biologist flagged over “credible concerns”

PLOS upgrades flag on controversial PACE chronic fatigue syndrome trial; authors “surprised”

PLOS ONE has issued an expression of concern after the authors of a controversial study about chronic fatigue syndrome declined to share some of their data.

In an unusual move, the journal included the authors’ response to the expression of concern (EOC), in which they strongly argue against the notice, and “do not accept that it is justified.”

In 2015, following public requests to review the data, the journal issued an “editor’s note” on the paper, noting the journal’s policy that authors make data and materials available.

There have been numerous requests for data from the “PACE” trial, as the clinical trial is known. Patients and advocates have long disputed the results, arguing that suggesting cognitive behavior and graded exercise therapy could cause harm.

In the latest notice, the journal says it consulted two editorial board members about the paper, a 2012 sub analysis of a controversial clinical trial on chronic fatigue syndrome. The journal then asked the authors to provide the data behind five tables, which would enable researchers to replicate the cost-effectiveness analyses the authors report for different therapies — including graded exercise therapy, which some patient advocates believe could be harmful.

As with previous requests for data, the authors refused to provide it, citing patient confidentiality and consent. The notice explains:

Continue reading PLOS upgrades flag on controversial PACE chronic fatigue syndrome trial; authors “surprised”

Journal flags paper about GMO foods over concerns about figures

A journal has flagged a paper by a researcher who has questioned the safety of genetically modified organisms, after receiving concerns that there were issues with some images.

In the 2006 paper, researchers led by Federico Infascelli, an animal nutrition researcher at the University of Naples, tested the blood of rabbits fed genetically modified soybeans. Starting in November 2015, however, the journal animal fielded concerns that gels appeared manipulated, and a figure legend differed from that in a thesis associated with the research.

This isn’t the first notice issued for Infascelli’s controversial work, which has been under scrutiny in recent years, including by Italian senator and biologist Elena Cattaneo. Last year, he was formally reprimanded by the University of Naples for including manipulated data in three papers.

Although the University of Naples concluded the image manipulations were “not a breach of scientific integrity,” the journal has issued a lengthy expression of concern about the paper:

Continue reading Journal flags paper about GMO foods over concerns about figures

No longer in limbo: Journal lifts 2015 expression of concern from chemistry paper

All too often, when an article is flagged by a journal that’s concerned about the findings, the notice lingers in limbo, leaving readers unclear whether or not to rely on the findings. One chemistry paper’s two-year stint in purgatory ended last month, when the journal lifted its expression of concern (EOC) and replaced it with a correction.

The journal chose to swap the 2015 EOC with a correction after the authors addressed its concerns in a follow-up paper, also published in Organic & Biomolecular Chemistry.

The journal’s executive editor Richard Kelly provided further insights about what happened:

Continue reading No longer in limbo: Journal lifts 2015 expression of concern from chemistry paper

Journal flags another paper by diabetes researcher who sued to stop retractions

It would seem that resorting to legal means to avoid editorial notices doesn’t always work.

We’re coming to that conclusion after seeing yet another notice for Mario Saad, based at the University of Campinas in São Paulo, Brazil. In this case, it’s an expression of concern from the Journal of Endocrinology, on a 2005 paper that lists Saad as the second-to-last author. According to the notice, the journal is concerned the paper contains spliced and duplicated images; although the authors offered to repeat the experiments, the journal considered that potential delay “unacceptable.”

Despite Saad’s legal efforts, he is now up to 11 retractions, along with multiple expressions of concern.

Here’s the full text of the notice (which is paywalled, tsk tsk):

Continue reading Journal flags another paper by diabetes researcher who sued to stop retractions

Stuck in limbo: What happens to papers flagged by journals as potentially problematic?

Hilda Bastian from the National Library of Medicine

Expressions of concern, as regular Retraction Watch readers will know, are rare but important signals in the scientific record. Neither retractions nor corrections, they alert readers that there may be an issue with a paper, but that the full story is not yet clear. But what ultimately happens to papers flagged by these editorial notices? How often are they eventually retracted or corrected, and how often do expressions of concern linger indefinitely? Hilda Bastian and two colleagues from the U.S. National Library of Medicine, which runs PubMed, recently set out to try to answer those questions. We talked to her about the project by email.

Retraction Watch (RW): The National Library of Medicine recently decided to index expressions of concern, which it hadn’t before. Why the change? Continue reading Stuck in limbo: What happens to papers flagged by journals as potentially problematic?

Researcher sued to stop retractions; he just earned two more and is now up to 11

The notices keep coming for diabetes researcher Mario Saad.

Diabetes has just retracted two more of his papers, both of which had been flagged by expressions of concern, citing problems with duplications. What’s more, the journal added another expression of concern to a 2009 paper on which Saad — based at the University of Campinas in São Paulo, Brazil — is listed as last author, again over concerns of duplication.

This isn’t Saad’s first run-in with the journal: In 2015, the researcher sued the publisher, the American Diabetes Association, after it issued expressions of concern for four of his papers. Later that year, a judge dismissed Saad’s defamation suit. The journal eventually retracted the papers.

The latest articles flagged by Diabetes appear to be part of an intricate publishing web, as the journal suggests all papers have used features of previous papers, and also include elements that have been republished by subsequent articles.

Here’s the first retraction notice, for “A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet–Induced Weight Loss:”

Continue reading Researcher sued to stop retractions; he just earned two more and is now up to 11

Plant journal flags fungus paper amid investigation

A journal has issued an expression of concern (EOC) for a recently published study after a probe identified “problems with the figure presentation.”

According to the EOC notice in New Phytologist, two figures in the paper contained “some anomalies,” and the corresponding author has acknowledged that there are problems with the images.

Here’s the EOC notice: Continue reading Plant journal flags fungus paper amid investigation

Catching up: Publisher to pull four papers by retraction record holder flagged years ago

the-laryngoscopeJournals published by Wiley are retracting four papers by Yoshitaka Fujii, the anesthesiology researcher with the most retracted scientific papers.

Retraction Watch readers will be familiar with Fujii’s case: He currently holds the number one spot on our leaderboard with more than 180 retractions, some of which are pending. (That’s nearly twice the number of retractions by the researcher in the #2 spot, Joachim Boldt.) 

Earlier this year, The Breast Journal and The Laryngoscope — both of which are published by Wiley-Blackwell — issued expressions of concern (EOCs) for a total of four papers by Fujii. All four papers were included in a 2012 analysis of 168 of Fujii’s studies by J. B. Carlisle, a consultant anesthetist in the UK, who concluded that the chance of much of Fujii’s data appearing the way it does naturally is

…the chance of selecting one particular atom from all the human bodies on earth.

Now, both journals are retracting the papers. 

A Wiley spokesperson told us: Continue reading Catching up: Publisher to pull four papers by retraction record holder flagged years ago

Prominent cancer researcher committed nearly 30 acts of misconduct

An investigation into the lab of a prominent cancer researcher in British Columbia has revealed nearly 30 acts of misconduct.   

As we detail in our latest feature for Science, the investigation, at the University of British Columbia (UBC), uncovered 29 instances of scientific misconduct, 16 of which were characterized as “serious,” according to university correspondence obtained by Retraction Watch.

The researcher, Sandra Dunn, is prominent in her field, but she left UBC in 2015 under unclear circumstances, shortly after it concluded its investigation. Dunn now heads a private company, Phoenix Molecular Designs, which says it develops therapies for cancer patients and lists local charities among its “partners and supporters.” While at UBC, Dunn obtained at least $1.1 million dollars in Canadian federal funding, some of which was used to support the falsified studies.

To some of the people involved, the most unsettling part of the incident is that it appears Dunn still receives support from Canadian charities. Continue reading Prominent cancer researcher committed nearly 30 acts of misconduct