Category: clinical study retractions

Fraud retraction appears for deceased Maryland dental researcher

osomoporeA former dental researcher at the University of Maryland, Baltimore, has lost a 2009 paper in the journal Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology for fabricating his data on an NIH-funded study.

The researcher, Mark A. Scheper, is not identified in the retraction notice as the person implicated in the university investigation. However, one of his co-authors confirmed his involvement. Scheper died in January 2014 at age 45 of natural causes, according to the Maryland State Medical Examiner.

The article was titled “The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac.” It appeared online in March 2009, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

According to the abstract: Continue reading Fraud retraction appears for deceased Maryland dental researcher

Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

circresA group of Harvard stem cell researchers who already have one retraction and an expression of concern now have a correction. This one’s in Circulation Research, and it involves an image that previously had been flagged as suspicious in our comments.

The group is led by Piero Anversa, who as we reported last year is one of two researchers suing Harvard because the institution’s investigation into their work

has cost them millions in a forfeited sale of their company, and job offers.

Continue reading Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

Former Pitt cancer researcher admits to faking findings

Dong Xiao
Dong Xiao

A former researcher at the University of Pittsburgh inflated the number of mice used in his experiments, and faked data in a number of images in a paper reporting the results, according to the Office of Research Integrity (ORI).

Dong Xiao admitting to having

intentionally fabricated data contained in a paper entitled ‘Guggulsterone inhibits prostate cancer growth via inactivation of Akt regulated by ATP citrate signaling,’ specifically Figure 6G,

the ORI reports. The paper was published in  in July 2014 in Oncotarget. Here’s Figure 6: Continue reading Former Pitt cancer researcher admits to faking findings

Retracted paper on herbicide-ovarian cancer connection republished

ehpA retracted 2008 paper originally flagged by Clare Francis has been republished in Environmental Health Perspectives with updated figures and new data.

According to the editor’s note appended to the newly published paper, there was no evidence of intentional misconduct on the part of the authors. The new paper went through peer review as an entirely new submission, and comes to the same conclusion as the original:  Continue reading Retracted paper on herbicide-ovarian cancer connection republished

Franken-paper from U.S. federal contractor heads to the grave

Image via Insomnia Cured Here.
Image via Insomnia Cured Here.

Hindawi journal PPAR Research has pulled a cancer immunology paper after discovering it contained almost no new information.

Instead, it was a Frankenstein-style stitch job, containing sentences ripped from 33 different papers. 18 of those ended up in the citations; for 15 more, the authors didn’t even do them that courtesy. You can see a meticulously color-coded call out here.

Here’s the notice for “A Role for PPARy in the Regulation of Cytokines in Immune Cells and Cancer”: Continue reading Franken-paper from U.S. federal contractor heads to the grave

Duplicate submission forces retraction of derm laser paper

jclasertherThe Journal of Cosmetic and Laser Therapy has retracted a 2014 paper by a group of South Korean researchers after determining that the authors had doubled up on their publishing odds by submitting the manuscript to a competing journal.

The article was titled “A comparative study of low-fluence 1064-nm Q-switched Nd:YAG laser with or without chemical peeling using Jessner’s solution in melasma patients,” and it purported to find that:

This study suggests Jessner’s peel is a safe and effective method in the early course of treatment for melasma when combined with low-fluence 1064-nm Q-switched Nd:YAG laser.

Continue reading Duplicate submission forces retraction of derm laser paper

Leading diabetes researcher corrects paper as more than a dozen studies are questioned on PubPeer

maelder
Kathrin Maedler

Prominent German diabetes researcher Kathrin Maedler has issued corrections on two papers, and told Retraction Watch she is in the process of defending the data on others.

14 of her papers have been critiqued by PubPeer commenters. The commentary, which spans from her graduate work in 2002 to a 2014 publication in Nature Medicine, includes questions about image manipulation and self-plagiarism.

Laborjournal’s blog (we have a column in their English-language publication) first flagged these suspicions in July 2014, after being approached by pseudonymous Clare Francis.

Here’s a comparison between figures in Maedler’s 2009 PLoS One paper, “Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis and Impairs β-Cell Mass,” and one she co-authored in 2006 in Diabetes, “Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets,” via PubPeer:  Continue reading Leading diabetes researcher corrects paper as more than a dozen studies are questioned on PubPeer

A ewe-turn: Researchers lose sleep, and paper, over miscounted sheep

Suspicious sheep via John Haslam
Suspicious sheep via John Haslam

A group of Chinese cardiologists at Capital Medical University have done a quick ewe-turn, pulling a paper after mixing up both the author order and wrongly reporting how many sheep were killed in the making of this experiment.

We covered another retraction from the CMU cardiology department in September. The sheep paper was published in October.

Here’s the notice for “Mosaic tissue-engineered porcine pulmonary artery valved conduit: long-term follow-up after implantation in an ovine model”: Continue reading A ewe-turn: Researchers lose sleep, and paper, over miscounted sheep

Paper on cranberries’ health benefits retracted after researcher forges authors’ names

Image via Bruce Foster.
Image via Bruce Foster.

A paper in Food Chemistry suggesting cranberry extract has healing properties was retracted after some of the authors complained they had no idea the paper was being published.

Here’s the notice for “Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits:” Continue reading Paper on cranberries’ health benefits retracted after researcher forges authors’ names

Thalidomide paper retracted for lab error

fertstertResearchers at the University of Pittsburgh have retracted a paper on using thalidomide, which led to an estimated 10,000 birth defects by the time the drug was pulled from the market in 1961, to prevent chemo-induced sterility.

Alkylating agents, which prevent DNA replication in cells, are a commonly-used cancer treatment. Unfortunately they also damage the ovaries and testes, sometimes causing infertility. The University of Pittsburgh scientists published a paper in Elsevier journal Fertility and Sterility in 2011 that suggested thalidomide, which causes severe birth defects when used during pregnancy, might help protect ovaries during chemo.

However, according to the notice, the authors tried and failed to replicate their results. They had two separate scientists who were not authors take a look at the results; everyone agreed that the original study incorrectly reported the number of primordial follicles, the precursor to mature eggs.

Here’s the notice for “Thalidomide treatment attenuates chemotherapy-induced gonadal toxicity”: Continue reading Thalidomide paper retracted for lab error