Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

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PLoS One and Nature Medicine have issued corrections for papers by Zhiguo Wang, the former Montreal Heart Institute researcher who resigned in September following an investigation into image manipulation in his lab. 

In September, PLoS One told us that they were investigating the paper. Here’s the text of the correction for “Transcriptional and Post-Transcriptional Mechanisms for Oncogenic Overexpression of Ether À Go-Go K+ Channel:” Continue reading Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

Why editors should stop ignoring anonymous whistleblowers: Our latest LabTimes column

A retraction notice appeared a few months ago in the Biophysical Journal:

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

This article has been retracted at the request of Edward Egelman, Editor-in-Chief.

The editors have noted that there is a substantial overlap of figures and text between this Biophysical Journal article and D. Rutkauskas, V. Novoderezkhin, R.J. Cogdell and R. van Grondelle. Fluorescence spectral fluctuations of single LH2 complexes from Rhodopseudomonas acidophila strain 10050. Biochemistry, 43 (2004) 4431–4438, doi:10.1021/bi0497648. The submission of this paper was inconsistent with the Biophysical Journal policy which states: “Manuscripts submitted to Biophysical Journal (BJ) must be original; papers that have already been published or are concurrently submitted elsewhere for publication are not acceptable for submission. This includes manuscripts previously submitted to BJ, as well as material that has been submitted to other journals while BJ is considering the manuscript. If some part of the work has appeared or will appear elsewhere, the authors must give the specific details of such appearances in the cover letter accompanying the BJ submission. If previously published illustrative material, such as figures or tables, must be included, the authors are responsible for obtaining the appropriate permissions from the publisher(s) before the material may be published in BJ”. We are therefore retracting the publication of the Biophysical Journal article.

Ordinarily, such duplications go to the bottom of our list of retractions to cover, despite how common they are. There’s usually less of a story behind them than there is behind a completely opaque notice, or behind one that sports a whiff of fraud. But they’re still important, as Bruce Chabner, the editor of The Oncologist, pointed out in a recent issue of his journal in which a duplication retraction appeared: Continue reading Why editors should stop ignoring anonymous whistleblowers: Our latest LabTimes column

Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Last month, we reported that the last three of six promised retractions by Zhiguo Wang, who was a researcher at the Montreal Heart Institute until the results of an Institute investigation forced him to resign in early September — would be in the Journal of Cellular Physiology. They’ve now appeared.

Here are the three notices, which are far more informative than the Journal of Biological Chemistry was — and which make it clear Wang acted alone: Continue reading Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Retraction comes as death of PI leads to lost records

The Journal of Experimental Medicine has retracted a 2011 article after the principal investigator’s home institution suggested that the PI might have manipulated his data. Complicating matters, the PI in this case died two weeks after the paper appeared and his notes have gone missing — making an affirmative declaration of fraud or honest error difficult.

Here’s the notice: Continue reading Retraction comes as death of PI leads to lost records

Retraction (in all but name) of flu paper raises eyebrows

When is a retraction not a retraction? Why, when it’s a correction, of course — like the one the journal Emerging Infectious Diseases issued this month:

In the article Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus (P. Bhoumik, A.L. Hughes), errors were made in selection of the hemagglutinin (HA) and neuraminidase (NA) sequences for the initial and subsequent data sets. As a result, the authors incorrectly concluded that the NA gene of the pandemic (H1N1) 2009 virus is of a more ancient lineage than the HA. Other researchers (and the authors) have not been able to reproduce the findings when using HA and NA matched pairs from viruses chosen on the basis of geography and time and correctly have pointed out errors in the data set that make the original conclusions invalid.

In other words, 1) the article was based largely on an error and 2) the central point could not be reproduced, two flaws that, at least in our book, usually constitute grounds for retraction.

The paper was written by Priyasma Bhoumik and Austin Hughes. Bhoumik, now a post-doc at Harvard, at the time was a PhD student at the University of South Carolina, where Hughes is a senior faculty member. Funding for the work came to Hughes from the National Institutes of Health, according to the original article.

We spoke with Hughes, who said that in this case, correction versus retraction is a distinction without a difference: Continue reading Retraction (in all but name) of flu paper raises eyebrows

Florida group loses second hypertension paper, but retraction notice stays mum on why

We’ve obviously gotten plenty of mileage out of our conversation last January with L. Henry Edmunds, the grumpypants editor of the Annals of Thoracic Surgery who told us that the reason behind an opaque retraction notice in his journal was “none of  [our] damn business.”

Still makes us chuckle.

That episode came to mind recently when we learned of a new retraction, this one in the journal Perfusion, involving the same lead researcher, anesthesiologist Felipe Urdaneta, whose work Edmunds had pulled. Continue reading Florida group loses second hypertension paper, but retraction notice stays mum on why

Science expresses “concern” about Stapel paper

A day after Tilburg University released its preliminary report on psychologist Diederik Stapel, Science has issued an “expression of concern” about one of his papers.

The 2011 article, titled  “Coping with Chaos: How Disordered Contexts Promote Stereotyping and Discrimination,” was written by Stapel and Siegwart Lindenberg, a Tilburg colleague with an appointment at the University of Groningen.

Here’s the notice, signed by Science editor Bruce Alberts: Continue reading Science expresses “concern” about Stapel paper

Stapel report finds faked data in at least 30 papers, possibly more

Our comment threads lit up today with news that the interim report on the misconduct investigation into Diederik Stapel has arrived — and what it says ain’t pretty. Continue reading Stapel report finds faked data in at least 30 papers, possibly more

Cancer journal retracts herbal medicine paper, citing misconduct probe

The journal Cancer Prevention Research has retracted a 2009 article by a group of scientists from the University of Kentucky after the institution determined that one of the figures in the article wasn’t kosher.

The article, “Psoralidin, an Herbal Molecule, Inhibits Phosphatidylinositol 3-Kinase–Mediated Akt Signaling in Androgen-Independent Prostate Cancer Cells,” has been cited 9 times, according to Thomson Scientific’s Web of Knowledge. Earlier iterations of the research were presented at two cancer meetings in 2008.

Continue reading Cancer journal retracts herbal medicine paper, citing misconduct probe

Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology

We’ve been following the case of Zhiguo Wang, the former Montreal Heart Institute researcher who was forced to resign his post in early September following an investigation into his work. At the time of that announcement, two retractions of the Wang group’s papers — which we had reported on in August — had appeared. The Institute said they had requested three more.

We figured that meant a total of five, although the Institute wouldn’t say which they were. So when we found out about a third retraction, in the Journal of Cell Science, we said it was the first of the remaining three.

We were wrong. Continue reading Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology