Category: clinical study retractions

JCO expresses concern over images from Spanish group that had aroused earlier concern

The Journal of Clinical Oncology has issued an expression of concern about a 2003 article by a group of researchers in Spain who appear to have had recurrent problems with images.

The paper has been cited 56 times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice:

It has been brought to our attention, regarding Figure 1, Part A, that similarity exists between bands 3, 4, and 5 of the top row and bands 1, 2, and 3 of the bottom row, including the presence of artifacts, in the April 15, 2003 article by [Jose] RomanGomez et al, entitled, “Cadherin-13, a Mediator of Calcium Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa” (J Clin Oncol 21:1472-1479, 2003).  This similarity has raised concerns about whether these rows represent independent data. We alerted the corresponding author, Dr. Roman-Gomez, of this concern, and he has repeated the experiment shown in the original Figure 1, with the results below. Although the results of the figure appear to be unchanged, we wish to inform the readers of this issue, so that they may make their own independent assessment.

Continue reading JCO expresses concern over images from Spanish group that had aroused earlier concern

Third retraction arrives for Alirio Melendez, this one in the Journal of Cellular Physiology

Alirio Melendez, the former National University of Singapore researcher who has already retracted two papers in the midst of an investigation into about 70 of his publications, has had a third retracted a third.

Here’s the notice from the Journal of Cellular Physiology: Continue reading Third retraction arrives for Alirio Melendez, this one in the Journal of Cellular Physiology

Salami slicing and heart attacks don’t mix: Duplication, lack of transparency lead to retraction

A group of French cardiology researchers have retracted a study of a potential way to rule out heart attacks, after it became clear they had used data from another study without alerting the journal.

In an unusually forthright letter accompanying the retraction of “Concomitant measurement of copeptin and high-sensitivity troponin for fast and reliable rule out of acute myocardial infarction,” originally published in Intensive Care Medicine, Bruno Riou and colleagues note: Continue reading Salami slicing and heart attacks don’t mix: Duplication, lack of transparency lead to retraction

A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

A partial retraction has joined the ten retractions and five corrections of Anil Potti’s papers, this one of a 2008 paper in Molecular Cancer Therapeutics. The move comes 14 months after the retraction of the Nature Medicine paper upon which much of the Molecular Cancer Therapeutics paper was based.

Here’s the notice: Continue reading A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

Three more retractions for resveratrol researcher Dipak Das, in free radical journals

Das, via UConn

The retraction count for Dipak Das, the resveratrol researcher whom the University of Connecticut found to have committed 145 counts of fabrication and falsification of data, has risen to eight with withdrawals by Free Radical Biology & Medicine and Free Radical Research.

The two Free Radical Biology & Medicine retractions, for “Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol” (cited 38 times, according to Thomson Scientific’s Web of Knowledge) and “Redox regulation of resveratrol-mediated switching of death signal into survival signal” (cited 32 times), are carefully detailed and read the same way: Continue reading Three more retractions for resveratrol researcher Dipak Das, in free radical journals

Rheumatology retracts lupus-cancer meta-analysis over multiple errors

Rheumatology has retracted a 2011 paper with too many errors to correct.

According to the notice, the article, titled “Meta-analysis of systemic lupus erythematosus and the risk of cervical neoplasia’, by Hongli Liu and colleagues at Huazhong University of Science and Technology in China, seems to have been deeply flawed: Continue reading Rheumatology retracts lupus-cancer meta-analysis over multiple errors

Rabbits needn’t worry about cell phones’ effects on their sperm count, say three retractions

If you’re a rabbit and you haven’t figured out where to carry your cell phone, your front pocket is just fine.

That’s what you could reasonably infer from the retraction of a paper in the International Journal of Andrology purporting to show that mobile phones affected rabbits’ sperm counts. The notice, signed by the journal’s editor, Ewa Rajpert-De Meyts (we added links): Continue reading Rabbits needn’t worry about cell phones’ effects on their sperm count, say three retractions

Paper linking vitamin C and reduced asthma retracted after authors find “severe” problems with data

It’s never a good sign when a paper has “severe” problems with its data. But when even the researchers are at a loss to explain how those problems made their way into the manuscript, well, that’s downright alarming.

Consider: The journal Clinical and Translational Allergy has retracted a 2011 article by researchers from Egypt and Finland, who have been studying the effects of vitamin C on childhood asthma. In a previous article, published in 2009 in Acta Paediatrica, members of the team reported that Continue reading Paper linking vitamin C and reduced asthma retracted after authors find “severe” problems with data

Authors retract paper claiming antidepressants prevent suicide

The authors of a study allegedly showing that antidepressants prevent suicide have retracted it over unspecified errors. Here’s the notice:

At the request of the authors and in agreement with the Editor-in-Chief and Wiley-Blackwell, the following article “Antidepressant medication prevents suicide in depression”. Acta Psychiatr Scand 2010;122:454–460 has been retracted. The retraction has been requested and agreed due to unintentional errors in the analysis of the data presented.

The original paper linked “data on the toxicological detection of antidepressants in 18 922 suicides in Sweden 1992–2003” to “registers of psychiatric hospitalization as well as registers with sociodemographic data.” It found: Continue reading Authors retract paper claiming antidepressants prevent suicide

Journal pulls four breast cancer papers for duplication

The journal Breast Cancer: Targets and Therapy, a Dove Medical Press title, has retracted four articles from a group of Indian researchers over what it said were “unacceptable levels” of duplication with other published work. (Such a construction leaves us wondering what might constitute “acceptable levels” of duplication, but that’s for a different post.)

The articles were submitted by Rajeev Singhai, who is listed as being with Grant Medical College and the Sir J J Group of Hospitals, in Mumbai. According to his After College page, Singhai received his PhD in 2011 and is now a research fellow.

As the notice states: Continue reading Journal pulls four breast cancer papers for duplication