Category: clinical study retractions

A rare event: Toronto Star retracts fear-mongering vaccine story

TorontoStarOriginalGardasilHeadlineFifteen days after publishing a widely-criticized article linking anecdotal health problems to the HPV vaccine Gardasil, the Toronto Star has issued a retraction.

The Page 1 story, “A wonder drug’s dark side,” was full of health horror stories from women who became sick “sometime after” the vaccine, as the retraction notes – twitching limbs, feeding tubes, even death. Each of these stories came from the Vaccine Adverse Event Reporting System, a public database of anecdotes maintained by the U.S. government to help monitor rare side effects that might emerge when the vaccine is given to millions of people.

In mining this database of self-reported illness, the Star failed to give equal weight to the large body of scientific evidence that says Gardasil has very low rates of adverse effects and a huge public health benefit. The publisher’s note both acknowledges the criticism and explains where the story went wrong:

Continue reading A rare event: Toronto Star retracts fear-mongering vaccine story

Misconduct forces retraction of health behavior paper

j behav medA pair of psychology researchers at West Virginia University have lost their 2013 article in the Journal of Behavioral Medicine after one of the authors was found to have cooked the data.

The paper, “Preference for immediate reinforcement over delayed reinforcement: relation between delay discounting and health behavior,” was written by Shane Melanko and Kevin Larkin. It examined whether people who place less importance on the future were also less likely to adopt healthy behaviors, which come with delayed benefits. Melanko, then a doctoral candidate under Larkin, was evidently at one time a psychology student of some promise.

That promise might go unfulfilled. According to the retraction notice: Continue reading Misconduct forces retraction of health behavior paper

More evidence scientists continue to cite retracted papers

Screen Shot 2015-02-17 at 2.38.46 PMA new paper in the MDPI journal Publications reports that the only controlled study on the effect of giving COPD patients Omega-3 has been cited 52 times since being retracted. Of those, only two mentioned the retraction.

In 2005, Chest published an article that found that COPD patients who took omega-3 supplements for 2 years experienced improvements in their condition, such as better walking tests and a decrease in sputum cytokines. But when an institutional investigation found the lead author had falsified the data, the journal retracted the paper in 2008.

That’s news to many researchers in the field. Among the 50 papers that cited the research after 2008 without stating it had been retracted, 20 included “specific data” from the paper, while the other 30 “cited the reference in passing.” Articles citing the retracted study have themselves been cited 947 times total, pointing to the ripple effect this kind of unwitting mention can have throughout the literature.

Continue reading More evidence scientists continue to cite retracted papers

First cut is the deepest: paper on incisional hernia sliced for duplication

jamcolsurgeonsThe authors of a 2014 paper in the Journal of the American College of Surgeons about incisional hernia have lost their article for being a duplicate submission.

The paper, “Impact on Quality of Life of Using an Onlay Mesh to Prevent Incisional Hernia in Midline Laparotomy: A Randomized Clinical Trial,” came from a group at the Parc Tauli University Hospital, part of the Universitat Autònoma de Barcelona, in Spain.

By duplicating another paper, the authors (three of which appear to be listed on both papers) committed “a severe abuse of the scientific publishing system,” according to the retraction notice: Continue reading First cut is the deepest: paper on incisional hernia sliced for duplication

Publisher and uni go head to head over disputed images in diabetes papers

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

The State University of Campinas University of Campinas and the American Diabetes Association disagree strongly over how to handle disputed images from faculty member Mario Saad, who is suing the ADA to prevent retraction of his papers.

While the State University of Campinas University of Campinas (Unicamp) acknowledges that 2 of Saad’s papers contain “mistakes”, it concluded there was “not an intention in the actions of the authors,” and the mistakes did not have a negative impact on the scientific community. Ultimately: “the studies published have their own strength, are healthy and were not artificially strengthened by the incorrect images.”

In response, however, Saad’s lawsuit says the ADA asked the school to reinvestigate the articles, and refused to accept any papers from Unicamp faculty in any ADA journals until the issues are resolved.

The ADA has issued four expressions of concern in Saad’s research published in its flagship journal, Diabetes. Saad’s lawsuit aims to prevent the journal from retracting those papers, and asks for monetary compensation.

Retraction Watch has obtained a report of the investigation by Unicamp and Saad’s lawsuit. You can read the full lawsuit here, and the investigation report here.

Here is an excerpt from the Unicamp’s findings: Continue reading Publisher and uni go head to head over disputed images in diabetes papers

Diabetes researcher sues journal to prevent retractions of papers cited more than 600 times

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

Mario A. Saad, who last year retracted a paper for plagiarism, is now suing the American Diabetes Association over four expressions of concern in its flagship journal, Diabetes.

As reported in the Boston Business Journal, Saad’s lawsuit claims that his institution, the State University of Campinas, investigated two articles at the journal’s behest. The American Diabetes Association was unhappy with the results, and asked the school to reopen the investigation, including two additional papers.

Saad is suing to prevent the journal from retracting the papers, in addition to monetary compensation.

Continue reading Diabetes researcher sues journal to prevent retractions of papers cited more than 600 times

Heart study bleeds into three papers, one retracted and one withdrawn

janWith the increasingly hectic pace of modern life, everybody is always on the look out for time-saving tricks and tips.

Scientists at the National University of Singapore and the Hong Kong Polytechnic University certainly found one, but we really can’t recommend it: doing one randomized controlled trial (RCT) with several outcomes, and publishing them as three separate 2014 papers with “considerable overlap.”

So far, one paper has been retracted, and another withdrawn.

Continue reading Heart study bleeds into three papers, one retracted and one withdrawn

He shoots, he…misses! Soccer injury paper gets red card for data errors

jsmsThe authors of a 2014 paper on soccer injuries have forfeited their publication after revealing that the foundation of the work was based on faulty data. (Look, we could have written about letting air out of balls, yadda yadda, but the Super Bowl has come and gone.)

The article, which appeared in the Journal of Science and Medicine in Sport, was written by a group in Denmark and Qatar led by Cristiano Eirale, a sports medicine researcher at the Aspetar-Qatar Orthopedic and Sports Medicine Hospital, in Doha. It showed goalies had a lower rate of injuries during training than field players.

Trouble was, someone called a foul.

Continue reading He shoots, he…misses! Soccer injury paper gets red card for data errors

A unicorn: Journal publishes euphemism-free plagiarism notice

af journ biomed researchIt’s always nice when a journal editor actually uses words the way they’re meant to be used instead of employing euphemisms.

In 2009, the African Journal of Biomedical Research published an article on the differences in heart rates when people ran backwards versus forwards. Unfortunately, five years later, the journal found out the paper was a reproduction of a 1994 Medicine & Science in Sports & Exercise paper. They contacted the authors and, when there was no response, published a straightforward and fairly detailed retraction.

According to managing editor Babafemi Olaleye, the original paper was received and handled by the founding editor of the journal. In April 2014, the managing editor of Medicine & Science in Sports and Exercise emailed the journal, stating that the paper had been copied wholesale.

Here’s the notice for “Comparison of Cardio-Pulmonary Responses to Forward and Backward Walking and Running”: Continue reading A unicorn: Journal publishes euphemism-free plagiarism notice

“Genuine error” sees expression of concern for vision loss paper

elsevierA duplicated figure has resulted in an expression of concern for a paper in the American Journal of Pathology on a treatment for ocular neovascularization, which causes vision loss.

According to the notice, the corresponding author, David Shima, now at University College London, brought his concern to the journal. He called it a “genuine error” and stated that all the findings had been reproduced.

Unfortunately, Shima claimed the original data are missing, because the institution that owned the information — Eyetech Research Center — has “since gone through several acquisitions.”

Ocular neovascularization occurs when growth signals in the eye stimulate the creation of many new blood vessels. Over time these blood vessels break, causing bleeding and scarring that limits vision. This is called “wet” macular degeneration.

The scientists found that giving patients drugs to limit two different growth factors at the same time is more effective than one at stopping the progression of AMD. This combination method is in stage three clinical trials, though with different drugs than the authors used here.

The paper, published in 2006, has been cited 130 times, according to Thomson Scientific’s Web of Knowledge. Here’s the EoC for “Inhibition of Platelet-Derived Growth Factor B Signaling Enhances the Efficacy of Anti-Vascular Endothelial Growth Factor Therapy in Multiple Models of Ocular Neovascularization”:

Continue reading “Genuine error” sees expression of concern for vision loss paper