Duke researcher with 7 retractions earns two Expressions of Concern

American Journal of Respiratory and Critical Care MedicineData issues continue to plague pulmonary papers co-authored by Duke University professor William Foster and former Duke researcher Erin Potts-Kant. Yesterday, the American Journal of Respiratory and Critical Care Medicine posted an Expression of Concern for two articles from the pair while the findings are “under review.”

The notice was published after the paper’s corresponding author, John Hollingsworth (also at Duke), told the journal that “some of the data published in these articles may be unreliable,” a term that we’ve gotten used to seeing from previous retractions.

Another Expression of Concern from the journal published earlier this year for another paper co-authored by Foster and Potts-Kant turned into a retraction months later. Hollingsworth was a co-author on that paper and another paper retracted from Environmental Health Perspectives in July.

Continue reading Duke researcher with 7 retractions earns two Expressions of Concern

Journal corrects CrossFit injury data in paper at center of lawsuit

XLargeThumb.00124278-201509000-00000.CVA study on the trendy and grueling workout regimen known as CrossFit has a correction concerning the number of participants hurt during 10 weeks of training. The paper has been the center of multiple lawsuits  — one by CrossFit, and one by a CrossFit gym owner — for allegedly over-inflating the risks associated with the regimen.

The original paper claimed that 9 of 54 participants dropped out of the study due to “overuse or injury.” The correction note says that just two left for those reasons.

The paper, published in The Journal of Strength and Conditioning Research actually concludes that CrossFit has some benefits. According to the abstract: Continue reading Journal corrects CrossFit injury data in paper at center of lawsuit

When the title states the wrong result, a paper gets corrected

PLOS ONE

Ever wonder why, on a round-trip, the leg home often feels shorter? A group of researchers found that’s only true in hindsight, as people look back on which leg felt shorter — the trouble is, when the paper first appeared, the title mistakenly stated the opposite was true.

One June 10, PLOS ONE published a paper entitled “The Return Trip Is Felt Longer Only Postdictively: A Psychophysiological Study of the Return Trip Effect”; 17 days later, it was republished under the correct title, “The Return Trip Is Felt Shorter Only Postdictively: A Psychophysiological Study of the Return Trip Effect.”

On July 15, the journal posted a correction notice explaining its mistake:

Continue reading When the title states the wrong result, a paper gets corrected

Re-analysis of controversial Paxil study shows drug “ineffective and unsafe” for teens

downloadThe antidepressant Paxil isn’t safe or effective for teens after all, says a re-analysis of a 2001 study published today in The BMJ.

The original 2001 paper in Journal of the American Academy of Child and Adolescent Psychiatry — study 329, as it’s known — helped greenlight use of the drug (generically known as paroxetine) in young people. But it’s faced accusations of ghostwriting, undisclosed conflicts of interest, and issues with data analysis since publication.

According to a BMJ feature, also published today: Continue reading Re-analysis of controversial Paxil study shows drug “ineffective and unsafe” for teens

Fourth retraction for Einstein oncologist due to image manipulations

home_cover (1)Two papers on a potential cancer drug have been retracted following an investigation that found “inappropriate manipulation of bands in gels.”

This makes four retractions by our count for Roman Perez-Soler, an oncologist at the Einstein College of Medicine, and for co-author Yi-He Ling, whose current affiliation is unknown.

Their previous two retractions, which we reported on in 2013, were also for image manipulation. At the time, Perez-Soler told us that Ling “accepted full responsibility for the changes” and he had “returned to his home country.”

The fresh retraction notes, from Molecular Pharmacology, provide a few specifics about the figures that were manipulated this time around.

Continue reading Fourth retraction for Einstein oncologist due to image manipulations

“Fabricated results” retract JAMA clinical trial, plus a sub-analysis of the data

Screen Shot 2015-09-14 at 11.00.11 AMA JAMA clinical trial that suggested a blood pressure drug could help patients increase their physical fitness, and a sub-analysis of those data, have been retracted after “an admission of fabricated results” by the first author on both papers.

The three-year clinical trial was published in JAMA in 2013.  It was retracted this morning.

The trial found ramipril helped patients with artery disease walk longer and with less pain, according to the abstract:

Among patients with intermittent claudication, 24-week treatment with ramipril resulted in significant increases in pain-free and maximum treadmill walking times compared with placebo. This was associated with a significant increase in the physical functioning component of the SF-36 score.

The retraction note explains how the fabricated data came to light: 

Continue reading “Fabricated results” retract JAMA clinical trial, plus a sub-analysis of the data

Anti-fish oil researcher netted two more retractions

Screen Shot 2015-08-17 at 10.11.25 AM
Brian Peskin

Earlier this year, Food and Nutrition Sciences retracted two papers from an author who criticized highly popular fish oil supplements after an additional round of peer review concluded his papers present a “biased interpretation,” among other issues.

Last year, Brian Peskin lost a paper for an “undeclared competing interest” — namely, that he held patents and directed a company associated with essential fatty acids.

In place of fish oil, Peskin touts plant-based supplements for treating cardiovascular disease. From the abstract of the freshly-retracted “Why Fish Oil Fails to Prevent or Improve CVD: A 21st Century Analysis,” he claims that Parent Essential Oils (PEOs) — such as alpha-linolenic acid, which can be converted into the EPA and DHA found in fish oil — “fulfill fish oil’s failed promise”: Continue reading Anti-fish oil researcher netted two more retractions

Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

American Journal of Physiology - Lung Cellular and Molecular PhysiologyAnother retraction and a correction that retracts two figures — ie, a partial retraction — have been posted for Duke University lung researchers, Erin Potts-Kant and Michael Foster.

These latest notices move the count up to 8.5 retractions for Potts-Kant and 7.5 for Foster (counting the partial retraction as 1/2), along with the correction for both. In both cases and in a familiar note from previous retractions, authors found “potential discrepancies” between two sets of data (partial retraction) and study figures that weren’t “reliable” (retraction).

The retraction comes after the authors discovered problems with three of the study figures. In the corrected paper, the authors were able to validate some of their findings after repeating the experiments, but retracted two of the study figures that they were “unable to verify.”

Continue reading Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

Divorce study felled by a coding error gets a second chance

home_cover (1)A journal has published a corrected version of a widely reported study linking severe illness and divorce rates after it was retracted in July due to a small coding error.

The original, headline-spawning conclusion was that the risk of divorce in a heterosexual marriage increases when the wife falls ill, but not the husband. The revised results — published again in the Journal of Health and Social Behavior, along with lengthy explanations from the authors and editors — are more nuanced: Gender only significantly correlates with divorce rate in the case of heart disease.

The authors’ note, from Iowa State’s Amelia Karraker and Kenzie Latham, at Indiana University-Purdue University Indianapolis, explains that the coding error led them to over-estimate how many marriages ended in divorce:

Continue reading Divorce study felled by a coding error gets a second chance

How long does it take to retract a paper? A look at the Eric Poehlman record

oriweb_logoIn 2005, the U.S. Office of Research Integrity announced that obesity researcher Eric Poehlman had committed misconduct in 10 published papers. You might think that all of those ten articles would have been retracted a decade later.

You’d be wrong. Only six of them have. Here’s what Elizabeth Wager (a member of the board of directors of The Center For Scientific Integrity, our parent non-profit organization) found when she went looking through the record. Continue reading How long does it take to retract a paper? A look at the Eric Poehlman record