Category: basic life sciences retractions

One image was duplicated in eight papers. Yes, eight.

A cancer journal has retracted a 2014 paper after discovering one image had been duplicated in seven other papers. That’s right—the same image appeared in a total of eight papers.

For some of the papers, the issues went beyond the single image. According to the retraction notice, several papers contained other duplicated images, as well as “overlapping text.”  The notice, published in October 2017 in Asian Pacific Journal of Cancer Prevention (APJCP), is essentially a letter PLOS ONE wrote to several journals, informing them of the issues in the eight papers, all published between 2014 and 2016. The letter mentions that one of the papers—a 2016 analysis in Korean Journal of Physiology (KJPP)—had already been retracted earlier this year. One author of the retracted KJPP paper confessed to using a company to prepare and submit the manuscript. Continue reading One image was duplicated in eight papers. Yes, eight.

University finds falsified data in PNAS gene therapy paper, authors retract

A university investigation has found falsified data in a 2011 paper about the side effects of a virus commonly used in gene therapy.

The authors are retracting the paper, but one co-author told Retraction Watch they stand by their main conclusions. According to Roland Herzog, a professor at the University of Florida (UF) College of Medicine and a co-author of the paper, the falsified data were related to a minor part of the paper.

The paper, “Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy,” was published in the Proceedings of the National Academy of Sciences (PNAS) in March 2011. All authors were affiliated with UF at the time; the handling editor, Kenneth Berns, is an emeritus professor at UF. The paper has been cited 50 times, according to Clarivate Analytics’ Web of Science. Continue reading University finds falsified data in PNAS gene therapy paper, authors retract

Caught Our Notice: A retraction that is “useful for investigators”

Via Wikimedia

Title:  Yeast CAF-1 assembles histone (H3-H4) 2 tetramers prior to DNA deposition

What Caught Our Attention: Informative retraction notices can be infrequent, but rarer still are notices that fulfill an oft-ignored function: To be a source of learning for others in the field. Here, the authors offer a nearly 800-word “detailed description of the issues” with “some observations that may be useful for investigators conducting similar studies.” These authors embraced the retraction process, carefully explaining their findings or the lack thereof, for each figure from their now-retracted paper.     Continue reading Caught Our Notice: A retraction that is “useful for investigators”

”Definitely embarrassing:” Nobel Laureate retracts non-reproducible paper in Nature journal

A Nobel Laureate has retracted a 2016 paper in Nature Chemistry that explored the origins of life on earth, after discovering the main conclusions were not correct.  

Some researchers who study the origins of life on Earth have hypothesized that RNA evolved before DNA or proteins.  If true, RNA would have needed a way to replicate without enzymes. The Nature Chemistry paper found that a certain type of peptide — which may have existed in our early history — made it possible for RNA to copy itself.

Jack W. Szostak—a professor of chemistry and chemical biology at Harvard University in Cambridge, Mass., who shared the 2009 Nobel Prize in Physiology or Medicine with Elizabeth Blackburn and Carol Greider for their pioneering research on aging—told us he was “incredibly excited” when he “thought we had at least a partial solution to this problem,” which researchers have been working on for over 50 years.  

But in subsequent experiments, Tivoli Olsen — a member of Szostak’s lab — could not reproduce the 2016 findings. When she reviewed the experiments from the Nature Chemistry paper, she found that the team had misinterpreted the initial data: The peptide in question did not appear to provide an environment that fostered RNA replication.

The errors were “definitely embarrassing,” Szostak told us: Continue reading ”Definitely embarrassing:” Nobel Laureate retracts non-reproducible paper in Nature journal

Caught Our Notice: Don’t count your chicken (genes) before they’re hatched

Via Wikimedia

Title: Molecular Characterization and Biological Activity of Interferon-α in Indian Peafowl (Pavo cristatus)

What Caught Our Attention: Soon after the paper appeared, the journal was alerted to the fact its findings were at odds with others in the field. When the editor approached the authors, everything fell apart: The authors couldn’t repeat the experiments, and “were also unsure of the molecular probes that were used in the study.” While it isn’t unusual to have doubts about data — since since research is a process of experimentation — it is odd not to know how your experiment was conducted. The paper was retracted less than two months after it was published. The manuscript was accepted two months after it was submitted in early May, theoretically giving reviewers enough time to catch these issues (along with the authors’ failure to cite relevant papers).  

Continue reading Caught Our Notice: Don’t count your chicken (genes) before they’re hatched

PLOS ONE retracts two papers one year after author says he okayed the move

PLOS ONE has retracted two 2014 papers from a group of researchers, after an institutional investigation confirmed image duplication. Although the authors initially asked to correct the figures in the two papers, they ultimately agreed with the decision to retract.

Mrinal K. Maiti—an associate professor at the Indian Institute of Technology at Kharagpur and corresponding author on the two now-retracted PLOS ONE papers—also corrected a 2016 paper published in PLOS ONE over figure-related errors. Maiti is the only author in common to all papers.

A spokesperson for the journal told us:
 Continue reading PLOS ONE retracts two papers one year after author says he okayed the move

Journal replaces anti-vaccine paper it retracted for missing conflicts, “number of errors”

A journal retracted a paper about how conflicts of interest might be influencing research into the link between vaccines and autism because — wait for it — the authors failed to disclose conflicts of interest.

According to the retraction notice, the editors retracted the paper without the authors’ agreement, because the authors had a host of personal and professional interests in the field they didn’t declare, such as being associated with organizations involved in autism and vaccine safety. What’s more, the article also contained “a number of errors, and mistakes of various types that raise concerns about the validity of the conclusion.”

But now, Science and Engineering Ethics has published a new version of the article that draws similar conclusions to the retracted one, albeit with an updated conflict of interest statement, among other changes. From the abstract of the revised version: Continue reading Journal replaces anti-vaccine paper it retracted for missing conflicts, “number of errors”

Caught Our Notice: Oops — paper included proofreader’s query

Via Wikimedia

Title: Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases

What Caught Our Attention: Everyone makes mistakes — but some are more amusing than others. In one recent correction, the publisher (Wiley) admitted to including a proofreader’s query in the published manuscript. But didn’t say what the query was.

We looked around, and think we found the added notes in the abstract on the PubMed entry (emphasis ours):  Continue reading Caught Our Notice: Oops — paper included proofreader’s query

Caught Our Notice: Dear peer reviewer, please read the methods section. Sincerely, everyone

Via Wikimedia

Title: Plasma contributes to the antimicrobial activity of whole blood against Mycobacterium tuberculosis

What Caught Our Attention: A big peer review (and perhaps academic mentorship) fail.  These researchers used the wrong anticoagulant for their blood samples, leading them to believe that certain blood components were fighting microbes. The authors counted the number of colonies to show how well or poorly Tuberculin mycobacteria were growing in cultures — but blood samples need anticoagulants to prevent clots before analysis, and they used an anticoagulant that actually prevented the microbes from colonizing. The authors (and reviewers) should have known this from  Continue reading Caught Our Notice: Dear peer reviewer, please read the methods section. Sincerely, everyone

A journal retracted a paper when authors couldn’t pay. Then it retracted the retraction.

Oops.

A plant journal recently retracted a 2017 paper, saying the authors couldn’t pay the page charges ($110/page). The notice has since disappeared, and the journal announced on Twitter Thursday it was issued in error. The paper is now intact on the journal’s site.

This isn’t the first time the journal has withdrawn a statement that authors couldn’t pay the page charges — we’ve discovered the journal removed a line to that effect from a 2015 retraction notice (although in that case, it left the retraction intact). Page charges, often required by traditional publishers, typically cover printing costs; they differ from article processing charges (APCs) levied by open-access journals, which cover the cost of publishing the paper and making it freely available.

We’ve contacted editors at the journal and its publisher, Taylor & Francis, to try to find out why there are mixed messages about author page charges. A spokesperson for the publisher said it was unable to respond before deadline, but it was looking into the matter:

I can confirm that we are committed to following [Committee on Publication Ethics] guidelines and that we are taking this issue seriously.

In the meantime, here’s what we know.

Continue reading A journal retracted a paper when authors couldn’t pay. Then it retracted the retraction.