Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

natureA team of Columbia University biologists has retracted a 2013 Nature paper on the molecular pathways underlying Alzheimer’s disease, the second retraction from the group after a postdoc faked data.

An April report from the Office of Research Integrity (ORI) found the a first author, former Columbia postdoc Ryousuke Fujita, responsible for “knowingly and intentionally fabricating and falsifying research in seventy-four (74) panels” in three papers: a 2011 Cell paper retracted in 2014, an unpublished manuscript, and this now-retracted Nature paper, “Integrative genomics identifies APOE e4 effectors in Alzheimer’s disease.”

The paper was touted in a Columbia University Medical Center press release as identifying “key molecular pathways” leading to late-onset Alzheimer’s disease. The paper fingered two potential molecular drug targets, as well.

Here is the full retraction notice: Continue reading Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

NIH neuroscientist loses second paper, again the result of first author misconduct

Stanley Rapoport. Source: NIH
Stanley Rapoport. Source: NIH

Stanley Rapoport, a neuroscientist in the National Institute on Aging, isn’t having a lot of luck with his first authors. One committed misconduct and cost him a paper in the journal Age last year, and now he’s lost another paper with a different first author, but for the exact same reason.

The latest paper, in Neurochemical Research, examined whether chronic doses of aspirin reduce brain inflammation. It has been cited 14 times, according to Thomson Scientific’s Web of Knowledge.

Here’s more from the note: Continue reading NIH neuroscientist loses second paper, again the result of first author misconduct

Wayne State neuroscientist fudged images in five papers

Teresita L. Briones
Teresita L. Briones

Teresita Briones, a former nursing professor at Wayne State University in Detroit who studied neuroscience, manipulated images in five papers, according to the Office of Research Integrity.

Briones, who focused on neuroplasticity: Continue reading Wayne State neuroscientist fudged images in five papers

SfN journal retracts paper, bans UPenn researchers over “data misrepresentation”

journal of neuroscienceThe Journal of Neuroscience has yanked an Alzheimer’s paper and banned three University of Pennsylvania authors from publishing there temporarily, following conflicting investigations by the university and the publisher, the Society for Neuroscience, into the data.

The 2011 paper looked into the cellular makeup of the characteristic plaques that develop in the brains of people with Alzheimer’s disease. It’s been cited 64 times, according to Thomson Scientific’s Web of Knowledge.

While the notice states that Penn’s investigation “supports the journal’s findings of data misrepresentation,” last author Virginia Lee said she asked the journal to simply issue a correction of the faulty data, since the findings are “extremely important” for the field and have been affirmed by a later paper. According to author John Trojanowski (who is married to and publishes regularly with Lee), he and Lee have been barred from publishing in Journal for Neuroscience for several years. Senior Co-author Edward Lee is out for a year [see update at the bottom of this post].

Lee provided us with a letter Vice Dean of Research Glen Gaulton sent to the journal (click here to read), in which he says an investigation found “no evidence of research misconduct” and the “errors…do not detract from or otherwise alter the conclusions of the manuscript.”

Continue reading SfN journal retracts paper, bans UPenn researchers over “data misrepresentation”

Neuro journal pulls comatose brain abstract due to “several mistakes”

clinical neurophysiologySwiss researchers have retracted an abstract in Clinical Neurophysiology because only one of them actually knew about the paper — and what he submitted had “several mistakes.”

The abstract, about electric impulses in the brain of comatose patients, originally appeared as a poster at the June 2014 joint meeting of multiple Swiss neuroscience societies. It was submitted by first author Alexandre Simonin, who lists his affiliation as the University Hospital of Lausanne, a Swiss hospital.

The meeting proceedings ran in the October issue of Clinical Neurophysiology. Besides the issues of authorship and errors, the notice also says the abstract “potentially conflicts with another publication,” suggesting the data might have already appeared in a paper.

Here’s the notice for “P02. Predicting the outcome of post-anoxic comatose patients based on single-trial EEG analysis”: Continue reading Neuro journal pulls comatose brain abstract due to “several mistakes”

Matlab mixup sinks Journal of Neuroscience paper

journal of neuroscienceA team of neuroscientists at University of Oregon and the University of California, San Diego (UCSD) have retracted a paper from The Journal of Neuroscience after realizing their analytic code contained an error.

The authors state in the notice that their conclusion remains accurate after correcting the mistake in the program Matlab. However, the paper — which examined the role of neuronal oscillations in working memory — still contained “some findings that we no longer believe to be robust.”

It’s a very useful notice: Continue reading Matlab mixup sinks Journal of Neuroscience paper

“Unacceptable level of text parallels” loses neuroscientist a paper, but not her PhD

maynoothWe should probably launch a new blog just on the euphemisms used for plagiarism.

A case of “inadequate procedural or methodological practices of citation or quotation” causing an “unacceptable level of text parallels” has sunk a review paper, but not a thesis, for a PhD who studied memory consolidation at Maynooth University in Ireland. According to a statement from the school, Jennifer Moore used “poor practice of citation and attribution” in both her thesis and in a review article published with her post-graduate P.I. in Reviews in the Neurosciences.

The review article, which has been cited four times, according to Thomson Scientific’s Web of Knowledge, will be retracted. Because there was no data fabrication and “no misleading of other scientists or laboratories,” the school will not be retracting the thesis nor taking away her PhD.

According to Google Scholar, the review has been cited 8 times. Moore now works as a neuropsychologist at the Great Ormond Street Hospital in London. We’ve contacted her for comment and will update if we hear back.

Here’s the notice for “Reconsolidation Revisited: A Review and Commentary on the Phenomenon”: Continue reading “Unacceptable level of text parallels” loses neuroscientist a paper, but not her PhD

Cut and paste and a PC crash: figure manipulations sink two papers

jnc

Two papers by an overlapping group of researchers in Italy have been retracted for manipulated figures.

In late 2013, perennial tipster Clare Francis sent their concerns about several papers, including the two that have been retracted, by authors who frequently publish together. One of the papers, in the Journal of Neurochemistry, is from a team led by Ferdinando Nicoletti; four other papers from the group have been criticized on PubPeer for image manipulation, which he addressed via email with us.

The second retracted paper, from the Journal of Immunology, has shares one author with the first: Patrizia Di Iorio of the University of Chieti, though according to Nicoletti she had no role in preparing the figures.

Here’s the April 2014 notice for “Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways” in the Journal of Neurochemistry. It’s behind a paywall, but the journal has assured us this is against policy and they will be fixing it shortly:
Continue reading Cut and paste and a PC crash: figure manipulations sink two papers

Stem cell researcher retracts neuron paper for “image aberrations”

embo journalJens Christian Schwamborn, a stem cell researcher at the University of Luxembourg, is retracting a 2007 paper on how to grow brain cells.

The paper, “Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity,” was published while Schwamborn was at Westfälische Wilhelms‐Universität Münster in Germany. An anonymous critic had sent questions about the study to Germany’s DFG in the middle of last year, and later to Paul Brookes, who posted them on PubMed Commons.

Those criticisms match the problems listed in the detailed notice: Continue reading Stem cell researcher retracts neuron paper for “image aberrations”

ORI sanctions former University of Chicago and UCSF scientists for faking findings

H. Rosie Xing
H. Rosie Xing

The stories behind several recent inscrutable retraction notices became a bit more clear today when the Office of Research Integrity (ORI) issued findings in cases involving former researchers at the University of Chicago and the University of California, San Francisco.

The ORI found that H. Rosie Xing, a former assistant professor at the University of Chicago, Continue reading ORI sanctions former University of Chicago and UCSF scientists for faking findings