A PNAS expression of concern appears — and so does its revealing backstory

pnas 1113When retraction notices and expressions of concern appear, particularly those that are opaque, we try our best to find out what’s behind them, whether it’s better explanations or the steps that led to moves. Today, we have one story in which we’ve been able to learn a lot more than usual.

In April, Bas van Steensel, Wendy Bickmore, Thomas Cremer, and Kerstin Bystricky sent a letter to about 80 leading labs in nuclear organization and steroid receptor biology. It began (we’ve added some relevant links): Continue reading A PNAS expression of concern appears — and so does its revealing backstory

Scientist in Ireland notches two mysterious retractions and a correction

Sinead Miggin, via NUIM
Sinead Miggin, via NUIM

Sinead Miggin, a biologist at the National University of Ireland Maynooth, has withdrawn two papers from the Journal of Biological Chemistry (JBC) and has corrected another paper, in the Proceedings of the National Academy of Sciences (PNAS).

Here’s the opaque JBC notice for “14-3-3ϵ and 14-3-3σ inhibit Toll-like receptor (TLR)-mediated proinflammatory cytokine induction,” a paper first published in November 2012: Continue reading Scientist in Ireland notches two mysterious retractions and a correction

Fudged figures sink breast cancer paper

oncogeneA prestigious cancer journal has pulled an article over “concerns” regarding some of the figures, which PubPeer commenters had tagged as suspect.

A few weeks after the paper was published on June 9, comments on PubPeer began accumulating. Commenters called out both potentially manipulated and repeated images. The exact timeline is not clear, because Oncogene does not list a date on the retraction notice, but by August 29 the paper had been retracted.

Here’s the notice for “IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer,” by researchers at Shanghai Jiaotong University School of Medicine and Ruijin Hospital, both in Shanghai, China, and the University of Michigan: Continue reading Fudged figures sink breast cancer paper

Diabetes researcher Cory Toth now up to nine retractions

neuroscienceCory Toth is up to nine retractions.

The University of Calgary researcher who told us earlier this year that he “will not be publishing in the world of science in the future” has retracted two papers from Neuroscience.

Here’s the notice for “Local erythropoietin signaling enhances regeneration in peripheral axons:” Continue reading Diabetes researcher Cory Toth now up to nine retractions

Danish committee rejects much of Klarlund Pedersen’s appeal of misconduct findings

Klarlund Pedersen
Klarlund Pedersen

The Danish Committees on Scientific Dishonesty (DCSD, Danish acronym UVVU) has partially reversed a December 2013 finding of misconduct against a scientist in Denmark, but has upheld most of its ruling.

Bente Klarlund Pedersen, whose case was tied up with that of Milena Penkowa, another scientist in Denmark found guilty of misconduct, committed misconduct in four of 12 articles examined, not six, the DCSD said in a statement last week.

Here’s the English summary (the DCSD does not name scientists under investigation publicly, but Pedersen has confirmed this is about her): Continue reading Danish committee rejects much of Klarlund Pedersen’s appeal of misconduct findings

Second retraction appears for former University of Florida ob-gyn subject to ORI probe

University of Florida
Chegini, via University of Florida

Nasser Chegini, an ob-gyn formerly on the faculty at the University of Florida who has been the subject of an Office of Research Integrity (ORI) inquiry for several years, has a second retraction.

Chegini is suspected of having used bogus data in some of his work — research backed in part by some $4 million in federal funding.

The new retraction involves a 2008 paper in Reproductive Sciences on which Chegini was senior author. Here’s the notice: Continue reading Second retraction appears for former University of Florida ob-gyn subject to ORI probe

Cell retraction of Alzheimer’s study is second for Tufts neuroscientist

Domnez_Gizem
Gizem Donmez, via Tufts

A researcher at Tufts University has retracted a paper in Cell, a year after retracting a study on a similar subject from the Journal of Biological Chemistry.

Here’s the notice for “SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10,” a 2010 paper by Tufts’ Gizem Donmez, MIT’s Leonard Guarante — of longevity research fame — and colleagues: Continue reading Cell retraction of Alzheimer’s study is second for Tufts neuroscientist

Serial figure fakers have expression of concern upgraded to a retraction

Another retraction has appeared up for frequent fliers Jun Li, Kailun Zhang and Jiahong Xia at Huazhong Science and Technology University in Wuhan, China.

We’ve covered them twice before, for a variety of retractions, corrections, and expressions of concern.

The retraction, in Clinical and Experimental Immunology, upgrades an expression of concern published earlier this year, and is the team’s fourth.

Here’s the notice for “CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice”: Continue reading Serial figure fakers have expression of concern upgraded to a retraction

PLOS ONE retraction notice blames deceased author for image manipulation

A 2011 paper in PLOS ONE has been retracted due to “inappropriately assembled” images. The issues, which were highlighted in a correction in TK, are attributed to the corresponding author, Paola Palozza, who has since passed away.

Here’s the notice for “Lycopene Inhibits NF-kB-Mediated IL-8 Expression and Changes Redox and PPARγ Signalling in Cigarette Smoke–Stimulated Macrophages,” which has been cited 33 times, according to Thomson Scientific’s Web of Knowledge: Continue reading PLOS ONE retraction notice blames deceased author for image manipulation

UT-Southwestern cancer research group notches ninth retraction

lung cancerA research team at the University of Texas-Southwestern that has retracted eight papers for image manipulation has retracted another, this one in Lung Cancer.

Here’s the notice for “Aberrant methylation of Reprimo in lung cancer,” published by Adi Gazdar’s group: Continue reading UT-Southwestern cancer research group notches ninth retraction