Mirror image in plant study flagged on PubPeer grows into retraction

djs_mpmi_28_9_cover-online.inddA 2010 paper on plant fungus has been retracted after a comment on PubPeer revealed that a study image had been flipped over and reused to represent two different treatments.

In May, a commenter pointed out the plants in Figure 2a of the paper in the journal Molecular Plant-Microbe Interactions “look remarkably similar.” A commenter writing under the name of corresponding author, Yukio Tosa at Kobe University in Japan, posted a response two days later agreeing with the assessment and stating that the paper should be retracted.

The notice reads: Continue reading Mirror image in plant study flagged on PubPeer grows into retraction

Science Signaling corrects data fudged by former UCSF student

afbb251f8bc8f71e26b313c77669d48fA paper containing data fudged by former University of California San Francisco grad student Peter Littlefield has been corrected. We knew that this was coming — last month, the Office of Research Integrity issued a report that Littlefield had admitted to misconduct, and agreed to a retraction or correction of the two affected papers.

Published in Science Signaling, “Structural analysis of the /HER3 heterodimer reveals the molecular basis for activating HER3 mutations” examined the structural details of a protein associated with cancer. It has been cited two times, according to Thomson Scientific’s Web of Knowledge.

According to the correction note, the concentration of a protein presented in one figure was “miscalculated;” in another figure, the error bars were “calculated incorrectly.”

A statement from the UCSF affirmed that principle investigator Natalie Jura has “not been implicated in any research misconduct finding,” and explains that Continue reading Science Signaling corrects data fudged by former UCSF student

“Fabricated results” retract JAMA clinical trial, plus a sub-analysis of the data

Screen Shot 2015-09-14 at 11.00.11 AMA JAMA clinical trial that suggested a blood pressure drug could help patients increase their physical fitness, and a sub-analysis of those data, have been retracted after “an admission of fabricated results” by the first author on both papers.

The three-year clinical trial was published in JAMA in 2013.  It was retracted this morning.

The trial found ramipril helped patients with artery disease walk longer and with less pain, according to the abstract:

Among patients with intermittent claudication, 24-week treatment with ramipril resulted in significant increases in pain-free and maximum treadmill walking times compared with placebo. This was associated with a significant increase in the physical functioning component of the SF-36 score.

The retraction note explains how the fabricated data came to light: 

Continue reading “Fabricated results” retract JAMA clinical trial, plus a sub-analysis of the data

CDC: Falsified data did not affect C. diff results

downloadDespite the fact that a former employee of the Oregon Health Authority falsified 56 case reports that were included in a report by the U.S. Centers for Disease Control and Prevention (CDC), a re-analysis has found that the results of the report remain valid.

The report included information about 10,342 cases of potentially deadly infections due to Clostridium difficile, so removing the cases affected by the misconduct — 57 in total — “did not” alter the results, according to an analysis published today by the CDC:

Continue reading CDC: Falsified data did not affect C. diff results

“Obviously stolen” figure squashes mosquito paper in author’s second retraction

jmr-cover2015The Journal of Mosquito Research has retracted a paper because it contains a figure that “was obviously stolen” from another paper.

The retracted paper’s first author Emtithal M. Abd El-Samiee is now up to two retractions, by our count. Last month, we reported on her fruit fly paper, felled by a faulty gene sequence. On the paper, she is listed as an entomologist at Cairo University.

The note tells us where the figure was stolen from:

Continue reading “Obviously stolen” figure squashes mosquito paper in author’s second retraction

Years after papers were withdrawn, JBC issues notices

Journal of Biological Chemistry.coverThe Journal of Biological Chemistry has posted withdrawal notices for six papers that had already been withdrawn, some more than a decade ago, in an effort to resolve “PubMed indexing problems.”

Each paper had been pulled by the author before it appeared in print, but still appeared online on the the journal’s website and in PubMed. 

By our count, the journal has posted six notices so far, and said we should expect to see more in the future.

Kaoru Sakabe the Manager of Publication Issues at the American Society for Biochemistry and Molecular Biology, which publishes JBC, provided a statement on the new withdrawal notices: Continue reading Years after papers were withdrawn, JBC issues notices

Retraction of grizzly bear-diabetes study follows departure of Amgen scientist for data manipulation

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The retracted paper made the cover of the August 2014 issue of the journal.

A study that looked to hibernating bears to understand the mechanisms behind diabetes has been retracted because an author based at the biotech company Amgen “manipulated specific experimental data” in two figures.

According to the The Wall Street Journal, Amgen discovered the manipulation while reviewing the data following publication of the paper,”Grizzly bears exhibit augmented insulin sensitivity while obese prior to a reversible insulin resistance during hibernation.” Published in Cell Metabolism last year, the paper has been cited 8 times, according to Thomson Scientific’s Web of Knowledge.

A press release from the journal last year — coverage in Science and Nature followed — explained the purpose of the study:

Continue reading Retraction of grizzly bear-diabetes study follows departure of Amgen scientist for data manipulation

Three retractions for Oregon neuroscience student investigated by ORI

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Journals have retracted three out of the four papers flagged by the Office of Research Integrity during its investigation of a University of Oregon neuroscience student, David Anderson.

Last month, when we first reported on the case, Anderson told us that he “made an error in judgment,” and took “full responsibility.” Two of the retraction notes say that Anderson “knowingly falsified data,” and cited the Office of Research Integrity case summary.

All three papers focus on memory.

The note for the first retraction, from the  Journal of Experimental Psychology: Human Perception and Performance, reveals exactly how Anderson falsified data in the paper. It’s paywalled — tsk, tsk — but printed here in full:
Continue reading Three retractions for Oregon neuroscience student investigated by ORI

Diederik Stapel ups count to 55 retractions

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Diederik Stapel

Dutch social psychologist and well-known fraudster Diederik Stapel is up to 55 retractions. He remains secure in his spot at #4 on our leaderboard.

The “fraudulent” Social Cognition article found, according to its abstract, that the more positively you perceive yourself, the less you need to compare yourself to other people. Conversely, negative thoughts were linked to more comparison to others. As an article in the New York Times points out, where Stapel’s faulty studies often succeeded is in telling us what we want to believe about the world.

Here’s the retraction note for the article:

Continue reading Diederik Stapel ups count to 55 retractions

Former UCSF grad student fudged data in two papers

ORIA former graduate student at the University of California, San Francisco “knowingly falsified and/or fabricated” data in two published papers, according to the Office of Research Integrity.

According to a case summary published this morning, Peter Littlefield was working on his PhD, studying the ways that cells respond to external signals, when he published the two problematic papers. He is the first author on the papers; Natalia Jura, whose lab he worked in, is the last on both.

The report’s findings are based on, among other sources, “the respondent’s admission.”

The first paper, “Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations” was published in Science Signaling and has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Three figures in the paper are problematic, says the ORI summary:

Continue reading Former UCSF grad student fudged data in two papers