Data manipulation flushes paper on gut bacteria

cell reportsData manipulation in a Cell Reports paper blew the importance of a kind of bacteria out of proportion.

Retracted this month — less than three months after it was published — the paper showed, according to a summary on the cover page:

B. subtilis is a symbiont that resides in the gut of C. elegans and generates nitric oxide that is essential for the host. Xiao et al. demonstrate that nitric oxide promotes defense against pathogenic bacteria by activating p38 MAPK, demonstrating the importance of commensal bacteria in host immunity.

But B. subtilis — a member of the Bacillaceae family — aren’t actually as plentiful as they appeared, explains the retraction notice for “Gut-Colonizing Bacteria Promote C. elegans Innate Immunity by Producing Nitric Oxide:”

Continue reading Data manipulation flushes paper on gut bacteria

Biologists earn 5th retraction following Swedish investigation

plos pathA team of biologists have earned a fifth retraction for a paper containing manipulated images, following an investigation by the Swedish government.

Last year, the investigation found that former Uppsala University doctoral student Apiruck Watthanasurorot had manipulated figures in five papers, four of which have already been retracted. Earlier this year, we reported that his supervisor, last author Kenneth Söderhäll, had requested PLOS Pathogens simply correct the fifth paper because independent groups have confirmed the findings. But according to the retraction notice for “Bacteria-Induced Dscam Isoforms of the Crustacean, Pacifastacus leniusculus,” Söderhäll has since agreed to the retraction:

Continue reading Biologists earn 5th retraction following Swedish investigation

Plant biologist’s paper pulled for falsification, three more questioned on PubPeer

PMBP Cover ImagePhysiology and Molecular Biology of Plants has retracted a paper about using Darjeeling tea clones against abiotic stress for problems with one of the figures.

The specific problem: “falsification/fabrication” of data underlying the figure, which the corresponding author — Sauren Das from the Indian Statistical Institute in Calcutta, West Bengal — couldn’t resolve. Das told us he denies the allegations made by the journal.

Meanwhile, three other papers by Das have been questioned on PubPeer

Let’s take a look at the retraction note: Continue reading Plant biologist’s paper pulled for falsification, three more questioned on PubPeer

Team in Japan earns third retraction for misconduct

JSRA team of researchers has earned its third retraction after an investigation at Oita University in Japan found instances of misconduct in their research.

The most recent notice mentions the investigation, and specifies that the first author, Satoshi Hagiwara, was responsible for the problematic figures in the paper. Hagiwara is also the first author on two retracted papers we reported on last year; one of the earlier retractions also mentions the investigation, but does not assign responsibility to any particular author. All three papers share three authors.

The retraction notice for “Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model,” published in the Journal of Surgical Research, explains the issues with the paper:

Continue reading Team in Japan earns third retraction for misconduct

Paper linking fecal transplants to obesity in rats retracted for faked data

Diabetes Cover

A paper linking the fecal microbiome to obesity has been retracted after it became clear that one of the co-authors faked some of the data.

The 2014 paper in Diabetes — which found that rats given fecal transplants from obese mice were more likely to become obese themselves if given a particular diet — was pulled after after an institutional investigation found a co-author guilty of falsifying data underlying one figure and fabricating the data of two others.

Co-author Yassine Sakar — formerly based at the French National Institute of Agronomic Research (INRA) in Paris, France — was found responsible for the misconduct. But an official from the institution said that some responsibility must also be shared by the corresponding author Mihai Covosa, who has since resigned from the institution.

Here’s the retraction notice: Continue reading Paper linking fecal transplants to obesity in rats retracted for faked data

Einstein grad student admits cooking data, settles with Office of Research Integrity

Screen Shot 2016-04-27 at 1.05.49 PMOne Friday in January, graduate student Meredyth Forbes was reviewing material for her dissertation with her mentor when she decided to make a confession.

She “burst out with a statement that some of the data was fabricated,” said Edward Burns, research integrity officer at the Albert Einstein College of Medicine, where Forbes worked. It was, Burns told Retraction Watch: Continue reading Einstein grad student admits cooking data, settles with Office of Research Integrity

Retraction count for Shigeaki Kato climbs to 39

Shigeaki Kato
Shigeaki Kato

We’ve found another retraction for Shigeaki Kato, number seven on our leaderboard.

Our count for Kato has now risen to 39; we added five retraction notices to our count for Kato last month. These notices follow an investigation at the University of Tokyo, where Kato used to work, which found 43 papers contained “likely altered or forged materials,” according to a 2013 news article from The Asahi Shimbun.

Here’s the retraction note for “1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP271B1 gene,” published in Molecular and Cellular Endocrinology:

Continue reading Retraction count for Shigeaki Kato climbs to 39

Singapore investigation leads to another retraction, correction for Harvard research fellow

Screen Shot 2016-03-25 at 8.12.49 AM

After an investigation found evidence of misconduct, a biologist has issued a third retraction.

Sudarsanareddy Lokireddy — now a research fellow at Harvard Medical School — “admitted falsification,” a Research Integrity Officer at Nanyang Technological University in Singapore told us in December. According to The Scientist, another journal has also published a correction that the authors had requested earlier.

The newly retracted paper is “Myostatin is a novel tumoral factor that induces cancer cachexia,” published in Biochemical Journal and cited 40 times, according to Thomson Reuters Web of Science. Here’s the retraction note:

Two more retractions bring total to 9 for neuroscience duo

Journal of Neuroscience CoverAfter the first author admitted to fraud, his colleagues have retracted a 2013 paper in the Journal of Neuroscience, as well as a 2015 book chapter about working memory.

The retractions come as part of a backstory of pulled papers authored by psychologist Edward Awh and his former graduate student David Anderson when he was based at the University of Oregon in Eugene. The pair retracted four papers last year after Anderson admitted to misconduct during an investigation by the U.S. Office of Research Integrity (and spoke to us about it last July). This led Awh — now based at the University of Chicago in Illinois — to take a second look at the other publications he’d co-authored with Anderson; earlier this year, Awh retracted two others, and informed us more would be coming, including the two most recent publications

First, let’s take a look at the retraction note for the Journal of Neuroscience paper, about remembered items and task performance: Continue reading Two more retractions bring total to 9 for neuroscience duo

Cell Press flags two papers after author confesses to fraud

Screen Shot 2016-04-11 at 8.45.56 PMNormally, when we see disputes over fraud allegations, it’s one author accusing another — but an unusual case at Cell has recently crossed our desk.

The journal has flagged a paper after an author confessed to committing fraud himself — but the corresponding author is disputing that confession, citing concerns about the confessor’s “motives and credibility.”

Independent labs are repeating the experiments to determine if the third author on the paper did, as he so claims, manipulate experiments. In the meantime, Cell and Molecular Cell have issued expressions of concern (EOCs) for two papers on which Yao-Yun Liang was a co-author. The notices cite an inquiry at Baylor College of Medicine, where the work was done, which was inconclusive, and recommended the journals take no action about the papers.

The EOCs are pretty much the same (both journals are published by Cell Press). Here’s the EOC that appears on “PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling,” published in 2006 by Cell and cited 251 times, according to Thomson Reuters Web of Science:

Continue reading Cell Press flags two papers after author confesses to fraud