Publisher flags more than 120 papers three and a half years after learning of problems

What started as a small editorial conundrum several years ago has turned into an expression of concern for dozens of papers in a medical journal, thanks to the work of an Australian physician and scientific sleuth.

In February 2022, we wrote about the decision by publisher Wolters Kluwer to retract a table that was missing in a paper in Medicine. In the end the journal pulled the whole article, which described a protocol for a clinical trial, because its authors had “not responded to multiple requests.”

The story left one reader intrigued. “I’ve never seen anything like that before,” said John Loadsman of the University of Sydney, an anesthesiologist and journal editor. “I thought, I’ve got to have a look.”

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Journal tags ‘impossible’ case report with short erratum

Last August, a reader alerted the editor of a medical journal to a recent case report “riddled with irreconcilable contradictions, medically impossible claims, fictional terminology, and ethical lapses.”

The paper, about a woman who allegedly suffered an aortic aneurysm rupture three days after giving birth, stated that written “informed consent was obtained from the patient for publication.” But the woman died less than two hours after arriving in the emergency room, according to the report.

“If she did not survive, she could not have provided consent post-event,” the concerned reader pointed out in an email to Riaz Agha, editor-in-chief of Annals of Medicine and Surgery, which published the case report in April.

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‘Tin Man Syndrome,’ five other case studies retracted following Retraction Watch coverage

A comparison of the images and an overlay, provided by a sleuth.

A journal has retracted a study on ‘Tin Man Syndrome’ plagiarized from a decade-old April Fools’ joke —  which the author now admits was fake.

On August 15, we wrote about a “rare case report” published in Medicine in which authors claimed they had encountered a case of “ectopia cordis interna” and described an asymptomatic man with his heart located in his abdomen. Sleuths believed the case report plagiarized images from a 2015 satirical paper describing a condition of the same name. 

A week later on August 22, Medicine, published by Wolters Kluwer, retracted the paper and five others — all published this year — with shared authors. None of the papers have been cited, according to Clarivate’s Web of Science. 

The retracted papers are:

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‘Tin Man Syndrome’ case plagiarized from hoax, sleuths say

A comparison of the images and an overlay, provided by a sleuth.

On April Fools’ Day 10 years ago, radiologist Matt Skalski took part in a website’s annual challenge to prank the radiology community by posting the case of a man with “ectopia cordis interna,” or “Tin Man Syndrome.” Unlike the fictitious metal character from the Wizard of Oz, Skalski’s satirical patient had a heart — in his abdomen. 

Now a group of researchers say they encountered the disease in real life, in a 22-year-old patient they claim has “no significant medical history.” 

The researchers based in Iraq published their “rare case report” in Medicine in July. 

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Editors won’t retract talc and cancer article J&J says is false in court

Steve Dorman/Flickr (CC BY 2.0)

A journal will not retract a paper linking use of talc-based baby powder to cancer, despite legal pressure from the pharmaceutical giant that made the product. 

A lawyer representing a unit of Johnson & Johnson in May asked editors of the Journal of Occupational and Environmental Medicine to retract a paper on cases of mesothelioma associated with cosmetic talc, following the court-ordered release of the identities of the people described in the article. 

The lawyer alleged many of the patients had other exposures to asbestos than cosmetic talc, rendering the article’s fundamental claims “false.” 

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Bad, Medicine: Journal publishes doubly-brutal retraction notice

A journal has retracted a paper it published earlier this year for pretty much every sin under the sun, scoring an own-goal in the process. 

The article, “Effects and safety of tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis,” was led by Yue Qiu, of the Beijing University of Chinese Medicine and appeared in Medicine on September 11.

The tl;dr version of this post: We have questions.

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Journals retract more than a dozen studies from China that may have used executed prisoners’ organs

Wendy Rogers, who has called attention to questionable papers

In the past month, PLOS ONE and Transplantation have retracted fifteen studies by authors in China because of suspicions that the authors may have used organs from executed prisoners.

All of the original studies — seven in Transplantation, and eight in PLOS ONE — were published between 2008 and 2014. Two involved kidney transplants, and the rest involved liver transplants. Two other journals, the Clinical Journal of the American Society of Nephrology and Kidney International, have recently issued expressions of concern for the same reason.

In an editorial explaining the seven retractions from its journal, the editors of Transplantation write:

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Fecal transplant paper pulled for “personal issue”

Last month, the Journal of Pediatric Gastroenterology and Nutrition pulled an article on fecal transplantation for a reason that, well, doesn’t pass the sniff test.

The paper, by Sonia Michail of Children’s Hospital Los Angeles, appeared online in October 2017 and described a randomized controlled trial of fecal transplants to treat kids with ulcerative colitis. (If you’re interested, here’s an overview of how fecal transplantation works.) The trial, or one awfully like it, is listed on ClinicalTrials.gov, and shows Michail as the lone investigator on the study, which is aiming to gather more than 100 participants.

But the journal retracted the article — which was the subject of a laudatory editorial in the journal pointing readers to the findings — with an entirely opaque statement, saying that the work   

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Hey journals, it is possible to quickly correct the record

Even when a paper is obviously flawed, it can take years for journals to take action. Some never do. But it doesn’t have to be that way.

On April 27, a reader emailed the editors of two journals, noting that each had recently published a paper by the same group of authors that appeared strikingly similar.

Four days later, on May 1, a representative at Medicine, the journal that published the most recent version of the paper, wrote the reader back, saying the paper was going to be retracted.

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Caught Our Notice: A paper mistakenly ID’d a patient. Its retraction notice did, too. (Oops!)

What Caught Our Attention: Last year, a journal retracted a paper about a child who developed a rare complication related to the inherited disorder Gaucher Disease, after realizing it had inadvertently identified the child. It wasn’t an immediately obvious mistake — the authors listed the drugs the patient was taking, and in the case of one drug, there was only one child in the world taking it. For anyone in the know, that would make the child’s identity clear.

So retracting the paper makes sense — but publishing a retraction notice that spells out the issue in detail, including the name of the drug and the fact the patient was the only pediatric recipient, did not. So last month, the Journal of Pediatric Hematology/Oncology corrected the retraction notice, removing the name of the drug. (Phew.)

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