“Falsified” data shelve two more drug studies from discredited U Colorado student

The authors of a pair of papers in Molecular Pharmaceutics are retracting them following an investigation at the University of Colorado Denver, which found a graduate student had faked data.

Rajendra Kadam was a prominent member of the Research lab of Uday B. Kompella, until the investigation revealed earlier this year that he had “falsified” data from a liquid chromatography-mass spectroscopy (LC-MS) machine for years.

So far, we’ve found four retractions (including the latest two) and one expression of concern for Kadam. There may be more on the way: Continue reading “Falsified” data shelve two more drug studies from discredited U Colorado student

Oregon grad student admits to faking data in four neuroscience papers

oriweb_logoA graduate student at the University of Oregon in Eugene has admitted to faking data that appeared in four published papers in the field of visual working memory, according to the Office of Research Integrity.

David Anderson’s supervisor at the time was Edward Awh, who has since moved to the University of Chicago.

Anderson told Retraction Watch that the misconduct stemmed from “an error in judgment”:

Continue reading Oregon grad student admits to faking data in four neuroscience papers

Penn State postdoc faked data in cancer manuscript

oriweb_logoA former postdoctoral fellow at Penn State University faked numerous data and analyses in a manuscript submitted to Molecular Cancer Research, according to the Office of Research Integrity (ORI).

In a notice released today, the ORI found Julie Massè: Continue reading Penn State postdoc faked data in cancer manuscript

UPitt investigation brings total retraction count to four for pair of cancer researchers

Journal of Biological Chemistry1An official inquiry by the University of Pittsburgh has led to two more retractions for a pair of cancer researchers, Tong Wu and Chang Han. By our count, the pair now have four retractions under their belt, all the result of the university investigation.

The Journal of Biological Chemistry published the notices earlier this month, after it was discovered the papers contained cropped panels, among other issues. Importantly, the two papers appear to even have shared some data.

One 2006 paper, “Modulation of Stat3 Activation by the Cytosolic Phospholipase A2α and Cyclooxygenase-2-controlled Prostaglandin E2 Signaling Pathway,” investigated the molecular actors in cancer growth, such as overexpression of cyclooxygenase-2 (COX-2). It has been cited 34 times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice:

Continue reading UPitt investigation brings total retraction count to four for pair of cancer researchers

Data “mismatch” and author’s illness pluck bird sex-ratio study from literature

coverInaccessible data and an author’s illness are to blame for the retraction of a paper on sex ratios of baby finches, according to the authors.

The paper, “Experimental evidence that maternal corticosterone controls adaptive offspring sex ratios,” published in Functional Ecology, outlined how a hormone in mother finches can “skew” the number of males vs females that hatch from the eggs in her nest.

But after questions about the data were raised, the authors were unable to address the “mismatch” between the experimental data and those that were published. Compounding the situation is the fact that, while working on the paper, first author Sarah Pryke at the Australian National University “was suffering from a medical condition that likely impaired her cognitive abilities,” according to a statement from Pryke’s co-authors.

An email to Pryke was met with an out-of-office reply:

Continue reading Data “mismatch” and author’s illness pluck bird sex-ratio study from literature

Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

Jacob Hanna
Jacob Hanna

Cell biologist Jacob Hanna, the highly cited stem cell researcher currently at the Weizmann Institute of Science,  has posted a long erratum for a 2005 paper in Blood for “inadvertent mistakes,” among other issues; soon after, Hanna’s team issued another erratum for a 2009 Cell Stem Cell paper.

There’s more to tell: Last month, commenters on PubPeer noticed that images from at least 10 of the research papers Hanna coauthored in seven journals — that commenters had posted on the image hosting website Imgur and linked to on PubPeer — had been deleted.

Imgur did not confirm whether these specific images had been deleted, but told Retraction Watch:

Continue reading Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

Duke lung researcher up to seven retractions

Enviromental Health Perspectives

More journals have pulled papers co-authored by researchers Erin Potts-Kant and Michael Foster, at Duke University, bringing the total up to seven for Potts-Kant and six for Foster.

Authors were unable to replicate the experiments after “concerns about the initial data from the animal physiology laboratory” led them to reanalyze source data, according to the note in Environmental Health Perspectives. The comparison showed “potential inconsistencies in the data,” which “significantly impact the overall conclusions of the manuscript.” Similar issues appear to have felled the pair’s other papers, including the other two recent retractions in the American Journal of Respiratory and Critical Care Medicine and the American Journal of Physiology – Lung Cellular and Molecular Physiology — but in the latter case, the discrepancies don’t affect the conclusion.

Potts-Kant was arrested on embezzlement charges in 2013. Authorities alleged that she stole almost $15,000 from Duke University.

Environmental Health Perspectives posted a retraction in July, for a 2012 paper that looked at the molecular underpinnings in airways that react to ozone.

Here’s the full notice:

Continue reading Duke lung researcher up to seven retractions

HIV postdoc faked data in published paper, 2 grants

Julia_B
Julia Bitzegeio

An HIV researcher has admitted to faking data in a published paper, a manuscript, and two grant applications, according to a notice released today by the the Office of Research Integrity (ORI).

Former postdoc Julia Bitzegeio faked data in a 2013 paper, published in the Journal of Virology, about how HIV adapts to interferon. In the paper, “the manipulation was really minor,” Theodora Hatziioannouprincipal investigator of the lab at the Aaron Diamond AIDS Research Center (ADARC) in New York City where Bitzegeio worked, told Retraction Watch. “She just made cosmetic changes.”

The paper will be corrected, Hatziioannou said. Bitzegeio has left her lab, and her future is somewhat less clear:

Continue reading HIV postdoc faked data in published paper, 2 grants

Gut paper retracted after university review says “figures cannot be validated by original data”

IBDA biologist at Case Western Reserve University School of Medicine in Ohio has retracted a paper from Inflammatory Bowel Diseases after a university review found the figures within it could not be “validated by original data.”

The 2010 paper, “Elevated IL-13Rα2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway,” concerns the elevated expression and role of an inflammatory protein in colon cancer cells.

According to the notice, corresponding author and biologist Alan Levine — who recently received a $3.9 million Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse — requested the retraction.

Here’s the full notice: Continue reading Gut paper retracted after university review says “figures cannot be validated by original data”

“Data fabrication and manipulation have occurred”: Taste bud paper soured by fraud

The Journal of NeuroscienceA 2013 paper on the neurological impact of flavors has been retracted from The Journal of Neuroscience. The retraction notice offers few details (which is typical for the journal), but a statement sent to us by the last author noted that an investigation at the University of Maryland “determined that data fabrication and manipulation have occurred in this study.”

Gustatory Stimuli Representing Different Perceptual Qualities Elicit Distinct Patterns of Neuropeptide Secretion from Taste Buds” examined the relationship between flavors and neuropeptides, molecules that send signals to the brain.

Here’s the retraction notice:

Continue reading “Data fabrication and manipulation have occurred”: Taste bud paper soured by fraud