Should we change our name to Mori Watch? Yet another retraction from cancer researcher

Earlier this week we reported on the latest retraction of an article by Naoki Mori, number 21 in a series. We could have waited a few days and saved ourselves some trouble.

The journal Leukemia Research has retracted a 2006 paper by Mori, titled “Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines.” From the notice, which is behind a paywall: Continue reading Should we change our name to Mori Watch? Yet another retraction from cancer researcher

So how often does medical consensus turn out to be wrong?

In a quote that has become part of medical school orientations everywhere, David Sackett, often referred to as the “father of evidence-based medicine,” once famously said:

Half of what you’ll learn in medical school will be shown to be either dead wrong or out of date within five years of your graduation; the trouble is that nobody can tell you which half–so the most important thing to learn is how to learn on your own.

Sackett, we are fairly sure, was making an intentionally wild estimate when he said “half.” [See note about these strikethroughs at bottom of post.]  But aA fascinating study out today in the Archives of Internal Medicine gives a clue as to the real figuresuggests that he may have been closer than any of us imagined. Continue reading So how often does medical consensus turn out to be wrong?

Geology retraction unearths a dead co-author and plagiarized image of “Himalayan” rock actually from Norway

The journal Geology has retracted a paper that, when it was published in May 2010, was hailed as a major step forward in understanding what happened when the Indian and Asian land masses collided millions of years ago. As The Hindu reported when the paper was first published:

Dr. [Anju] Pandey and her colleagues used sophisticated analytical techniques to demonstrate the occurrence of relict majorite, a variety of mineral garnet, in rocks collected from the Himalayas. Majorite is stable only under ultra-high pressure conditions, meaning that it must have been formed very deep down in the Earth’s crust, before surfacing millions of years later.

“Our findings are significant because researchers have disagreed about the depth of subduction of the Indian plate beneath Asia,” said Dr. Pandey.

In fact, the previous depth estimates conflicted with estimates based on computer models. The new results suggest that the leading edge of the Indian plate sank to a depth around double that of previous estimates.

“Our results are backed up by computer modelling and will radically improve our understanding of the subduction of the Indian continental crust beneath the Himalayas,” said Pandey, according to an NOC release.

It turns out, however, that as best as anyone can tell, the key data are from Norway, not the Himalayas, and were published in 1998 by another group. According to the retraction notice, which appears in the May 2011 issue (link to 1998 paper added): Continue reading Geology retraction unearths a dead co-author and plagiarized image of “Himalayan” rock actually from Norway

Idea retraction: Did Picasso suffer migraines? Do ‘guitar nipple,’ ‘cello scrotum’ exist? Ask pigeons

Pablo Picasso, 1962, via Wikimedia

Cephalalgia published a lovely piece online this month. The abstract is a refreshing bit of honesty:

It is widely believed that Pablo Picasso suffered from migraine. The main cause for this is our suggestion made 10 years ago that some of Picasso’s paintings resemble migraine auras. Here we critically look back at our own hypothesis. We conclude that, although the idea is still fascinating, there is no proof of Picasso suffering from migraine with aura.

In other words, say authors Michel Ferrari and Joost Haan: Go ahead, blame us for this important clinical finding, which we first described in an editorial in Cephalalgia in 2000. We’re retracting the idea, but not before we have some fun with it.

So we figured we’d do the same.

The authors describe a number of famous cases of historical diagnoses such as Hildegard of Bingen, an abbess and mystic of the 12th century whose work has led some to suggest she was a migraneur. It’s difficult to confirm such diagnoses, of course, and the authors draw a parallel to other pronouncements by doctors: Continue reading Idea retraction: Did Picasso suffer migraines? Do ‘guitar nipple,’ ‘cello scrotum’ exist? Ask pigeons

Science publishes replication of Marc Hauser study, says results hold up

There has been some news over the past few weeks about Marc Hauser, the Harvard psychologist found guilty of misconduct by the university last year. First, because Harvard had listed him in a course catalog, The Crimson said that he might be teaching again, following a ban. But that turned out not to be the case, as The Boston Globe reported.

Today, Science lifted the embargo on a paper by Hauser and Justin Wood, now of the University of Southern California, showing that results published in the journal in 2007 — and later questioned — have held up. The abstract: Continue reading Science publishes replication of Marc Hauser study, says results hold up

Remember William Hamman, the pilot who claimed to be a cardiologist? A retraction appears

In December, we reported on the case of William Hamman:

It’s a mind-boggling story: A United Airlines pilot claims to be a cardiologist and was eagerly sought after for medical conferences at which he taught doctors teamwork. He shared millions in grants, according to the Associated Press. But as the AP reports, William Hamman wasn’t a cardiologist at all, having never even finished medical school.

Hamman had published at least six papers using false credentials, including an MD and a PhD. In December, Jean Gayton Carroll, editor in chief of Quality Management in Health Care, told us that the journal would be “reviewing and evaluating” a paper by Hamman it published last year, “Using in situ simulation to identify and resolve latent environmental threats to patients safety: case study involving operational changes in a labor and delivery ward.” That review, we learned today, has led to a retraction.

According to the notice, which is refreshingly detailed (we added a link): Continue reading Remember William Hamman, the pilot who claimed to be a cardiologist? A retraction appears

Forget chocolate on Valentine’s Day, try semen, says Surgery News editor. Retraction, resignation follow

We have a bizarre tale to relate involving the journal Surgery News, which recently lost its editor-in-chief over a rather strange editorial he wrote in the February issue of the magazine.

The ill-fated — and, we’ll stipulate, ill-advised — commentary has led to a de facto retraction of the entire publication — meaning that although no retraction notice exists that we’re aware of, neither does the issue exist in the publication’s archives.

But first, some important background. Surgery News is a trade magazine with a complicated structure. The publication, which describes itself as “the official newspaper of the American College of Surgeons [ACS],” is published by Elsevier, which supplies medical news through its International Medical News Group division. The society provides its own news, as well as the lead editor, a surgeon, who until recently was Lazar Greenfield. Greenfield, of the University of Michigan, also happens to be the president-elect of the ACS, twin responsibilities that put him at the pinnacle of influence for his specialty.

Now back to the offending editorial, which we’ll bring you in its entirety since 1) we think given the events that you should read the whole thing, and 2) because the ACS has taken the entire February issue off its website we can’t link to it even if we wanted to (more on that later). Under the heading “Gut Feelings,” Greenfield wrote (we added links): Continue reading Forget chocolate on Valentine’s Day, try semen, says Surgery News editor. Retraction, resignation follow

Another Cell retraction, and more questions than answers

A new retraction has appeared in the journal Cell. The article, “DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance,” had initially appeared in February 2009.

According to the notice: Continue reading Another Cell retraction, and more questions than answers

Unfortunate timing: Journal retracts cover image, citing tsunami in Japan

It’s an unusual move: Pediatric Allergy and Immunology has switched out the cover image in the online versions of its March issue, after realizing that likening allergies to a tsunami while Japan is struggling with the devastating effects of a real-life disaster could be “open to misinterpretation.” From an editor’s note: Continue reading Unfortunate timing: Journal retracts cover image, citing tsunami in Japan

Freedom from Information Act? Another JBC retraction untarnished by any facts

There’s helpful but uninformative:

Ivan: What’s the weather like today?

Adam: Sunny.

And then there’s uninformative as served up by the Journal of Biological Chemistry.

We’ve already recounted one teeth-grinding experience with the JBC, a publication of the American Society for Biochemistry and Molecular Biology. The case involved two papers in JBC by Axel Ullrich, an esteemed cancer researcher at the Max Planck Institute in Germany. According to Ullrich, one of his then-postdocs, Naohito Aoki, had manipulated figures that appeared in the papers, necessitating their retraction.

Round two involves another JBC retraction of a 2000 paper by Aoki and co-author Tsukasa Matsuda, titled ‘A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b.’ The paper has been cited more than 100 times, according to Thomson Scientific’s Web of Knowledge.

According to the notice: Continue reading Freedom from Information Act? Another JBC retraction untarnished by any facts