Science retracts paper after Nobel laureate’s lab can’t replicate results

Science is retracting a 2014 paper from the lab of a Nobel winner after replication attempts failed to conclusively support the original results.

In January, Bruce Beutler, an immunologist at University of Texas Southwestern Medical Center and winner of the 2011 Nobel Prize in Physiology or Medicine, emailed Science editor-in-chief Jeremy Berg to report that attempts to replicate the findings in “MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses” had weakened his confidence in original results. The paper had found that virus-like elements in the human genome play an important role in the immune system’s response to pathogens.

Although Beutler and several co-authors requested retraction right off the bat, the journal discovered that two co-authors disagreed, which Berg told us drew out the retraction process. In an attempt to resolve the situation, the journal waited for Beutler’s lab to perform another replication attempt. Those findings were inconclusive and the dissenting authors continued to push back against retraction.

Berg told us:

Continue reading Science retracts paper after Nobel laureate’s lab can’t replicate results

Caught Our Notice: Is “miscommunication of the rejection” the new euphemism for “paper accepted”?

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When Retraction Watch began in 2010, our co-founders Ivan Oransky and Adam Marcus quickly realized they couldn’t keep up with the hundreds of retractions that appeared each year.  And the problem has only gotten worse — although we’ve added staff, the number of retractions issued each year has increased dramatically. According to our growing database, more than 1,300 retractions were issued last year (and that doesn’t include expressions of concern and errata). So to get new notices in front of readers more quickly, we’ve started a new feature called “Caught our Notice,” where we highlight a recent notice that stood out from the others. If you have any information about what happened, feel free to contact us at [email protected].

TitleUpregulated Expression of Circulating MicroRNAs in Kidney Transplant Recipients With Interstitial Fibrosis and Tubular Atrophy

What caught our attentionContinue reading Caught Our Notice: Is “miscommunication of the rejection” the new euphemism for “paper accepted”?

Florida researcher “cherry picked” data, university investigation finds

Credit: University of Florida

A journal has retracted a 2014 paper after a university investigation found that the first author only reported certain data points that supported the paper’s conclusion.

Based on a whistleblower’s tip, the University of Florida investigated work by Huabei Jiang, a professor of biomedical engineering, and Lei Yao, a former postdoc and scientist in Jiang’s lab, for research misconduct. According to documents obtained by Retraction Watch through a  public records request, in 2015 Yao confessed to selectively choosing data in an email to the whistleblower. Continue reading Florida researcher “cherry picked” data, university investigation finds

Unnamed institution makes baffling retraction requests, journals comply

Two journals are retracting papers published by researchers affiliated with Children’s Hospital Los Angeles (CHLA).

To be frank, we’re baffled by most of this story. The retraction notices say “the institution” requested the retractions, but don’t name it; the first and last authors are also affiliated with the University of Southern California, as well as CHLA. Neither journal will say which institution sent the request, and USC and CHLA have each declined to comment on the retractions.

Here’s what we do know: Continue reading Unnamed institution makes baffling retraction requests, journals comply

Caught Our Notice: An “absolutely perfect retraction”

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When Retraction Watch began in 2010, our co-founders Ivan Oransky and Adam Marcus quickly realized they couldn’t keep up with the hundreds of retractions that appeared each year.  And the problem has only gotten worse — although we’ve added staff, the number of retractions issued each year has increased dramatically. According to our growing database, more than 1300 retractions were issued last year (and that doesn’t include expressions of concern and errata). So to get new notices in front of readers more quickly, we’ve started a new feature called “Caught our Notice,” where we highlight a recent notice that stood out from the others. If you have any information about what happened, feel free to contact us at [email protected].

Title: Skeletal muscle-specific CPT1 deficiency elevates lipotoxic intermediates but preserves insulin sensitivity

What caught our attention:  Continue reading Caught Our Notice: An “absolutely perfect retraction”

Retract, replace, retract: Beleaguered food researcher pulls article from JAMA journal (again)

Brian Wansink

A high-profile food researcher who’s faced heavy criticism about his work has retracted the revised version of an article he’d already retracted last month.

Yes, you read that right: Brian Wansink at Cornell University retracted the original article from JAMA Pediatrics in September, replacing it with a revised version. Now he’s retracting the revised version, citing a major error: The study, which reported children were more likely to choose an apple over a cookie if the apple included an Elmo sticker, was conducted in children 3-5 years old, not 8-11, as the study reported.

Although Wansink told BuzzFeed he asked the journal to retract the paper, Annette Flanagin, Executive Managing Editor for The JAMA Network, told us the editors requested the retraction:

Continue reading Retract, replace, retract: Beleaguered food researcher pulls article from JAMA journal (again)

After journal retracts their paper, authors post rebuttal on arXiv

In July 2017, just days after accepting and publishing a paper, a physics journal discovered several scientific errors” and decided to retract it.

But the authorsAlexander Kholmetskii and Tolga Yarman—strongly objected to the journal’s decision, so much so they published a detailed rebuttal to the retraction on the preprint server arXiv.

The paper explores a new principle related to Einstein’s theory of relativity. According to the authors, after the Canadian Journal of Physics notified them on July 17 about the decision to retract the paper, they asked the editor to publish their objection “to defend our sound point of view, and beyond this, our scientific reputation.” But Kholmetskiiwho lists his affiliation at Belarus State University in Minsk, and Yarman, a professor at Okan University in Istanbul—told us that the editor found their response “inappropriate.” As a result, the authors turned to aiXiv to protest the retraction.

Here’s the retraction notice for “Conservative relativity principle and energy-momentum conservation in a superimposed gravitational and electric field:” Continue reading After journal retracts their paper, authors post rebuttal on arXiv

Ethical concerns arise for head of controversial stem cell clinic

Geeta Shroff. Photo credit: Nutech Mediworld

Journals are raising ethical concerns about the research of a doctor who offers controversial embryonic stem cell treatments.

Two journals have issued expressions of concern for three papers by Geeta Shroff, who was the subject of a 2012 CNN investigative documentary. All cite ethical concerns; one mentions the potential link between the procedure the authors describe and a risk of forming teratomas, a type of tumor. Shroff has objected to all three notices.

Shroff, a doctor offering controversial embryonic stem cell treatments at her New Delhi clinic, Nutech Mediworld, has said that for years she couldn’t find opportunities to present her research to the medical community. Continue reading Ethical concerns arise for head of controversial stem cell clinic

Caught Our Notice: Another retraction for researcher paid $100k to leave uni

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When Retraction Watch began in 2010, our co-founders Ivan Oransky and Adam Marcus quickly realized they couldn’t keep up with the hundreds of retractions that appeared each year.  And the problem has only gotten worse — although we’ve added staff, the number of retractions issued each year has increased dramatically. According to our growing database, just shy of 1,000 retractions were issued last year (and that doesn’t include expressions of concern and errata). So to get new notices in front of readers more quickly, we’ve started a new feature called “Caught our Notice,” where we highlight a recent notice that stood out from the others. If you have any information about what happened, feel free to contact us at [email protected].

Title:  Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway  and  Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway 

What caught our attention:

Continue reading Caught Our Notice: Another retraction for researcher paid $100k to leave uni

Researcher apologizes for ignoring early warnings about earthquake data

In 2016, three researchers published data they had collected on a series of devastating earthquakes that hit Japan earlier that year.

But, in late September 2017, one of the authors—Hiroyuki Goto—revealed that the Kumamoto Earthquake data contained “wide reaching errors”—and an outside expert had warned him the data might be problematic nine months earlier.  

Goto, an associate professor in the Disaster Prevention Research Institute at Kyoto University, issued two statements in which he acknowledged the errors, but did not indicate how they occurred. According to The Japan Times, Japan’s Ministry of Education, Culture, Sports, Science and Technology is investigating whether the data “was falsified or fabricated due to inconsistencies with other readings taken nearby.” A report in another Japanese paper, The Mainichi, notes that Osaka University—where one of the authors, Yoshiya Hata, works—is looking into the matter as well.

Continue reading Researcher apologizes for ignoring early warnings about earthquake data