Category: by journal

Journal alerts readers to “technical criticism” of CRISPR study

A Nature journal has posted a editor’s note to a recent letter on potential unintended consequences of CRISPR gene editing, after an executive at a company trying to commercialize the technology said the paper should be retracted.

The original article, published on May 30 as a correspondence in Nature Methods, suggested that using CRISPR in mice can lead to unexpected mutations. But last week, the journal added an “Editorial note” online. Nature Methods says the notice is not an expression of concern, which would be a stronger suggestion that the paper is problematic; it simply wants to alert readers to the fact that, as the note states:

Continue reading Journal alerts readers to “technical criticism” of CRISPR study

Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says

A 2016 study in New England Journal of Medicine has received a substantial correction, which affected several aspects of the article.

Typically, an error that affects so much of a paper would undermine the results (and possibly lead to a retraction). But in this case, the revised dose calculations actually strengthened the findings, according to the first author.

The NEJM study aimed to clarify whether patients with a neuromuscular disease called myasthenia gravis benefit from a surgical procedure to remove the thymus. About half of the patients received surgery plus the steroid prednisone, while the rest only received the steroid. The researchers found patients who received the surgery fared better.

Shortly after the paper was published in August 2016, the authors discovered an error in the calculation of the average prednisone dose. According to Gil Wolfe, the first author of the paper, when the researchers corrected the error: Continue reading Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says

NIH researcher doctored 11 figures in 2016 paper, says ORI

A former Research Training Awardee at the National Institutes of Health “falsified and/or fabricated data” in 11 figures in a 2016 paper, according to the U.S. Office of Research Integrity.

This is the first finding of misconduct issued this year by the ORI.

According to the finding, published in the Federal Register, Brandi M. Baughman — formerly at the National Institute of Environmental and Health Sciences (NIEHS) — tweaked data and text in a PLOS ONE paper about screening for compounds that inhibit an enzyme known as inositol phosphate kinase. According to the notice, however, some of those experiments didn’t proceed as described:

Continue reading NIH researcher doctored 11 figures in 2016 paper, says ORI

Former prof fudged dozens of images, says university

On Dec. 2, 2013, Alison Lakin, the research integrity officer at the University of Colorado Denver, received a concerning email.

The emailer was alleging several problems in a 2012 paper in the Journal of Clinical Investigation, co-authored by one of its high-profile faculty members. Lakin discussed the allegations with some administrators and agreed they had merit; Lakin sequestered an author’s laptop and other materials. Over the next few months, the university learned of additional allegations affecting other papers — and discovered even more serious problems in the JCI paper. Namely, the first author had inserted changes to 21 figures in the paper after submitting it, without alerting the other authors, journal, or reviewers.

That journal retracted the paper this month, citing numerous problems:

Continue reading Former prof fudged dozens of images, says university

Journal hit by citation scandal named among top in field

It’s been a mixed year for Wiley’s Land Degradation & Development.

Following accusations of citation irregularities at the journal (whose its Impact Factor rose dramatically from 3.089 in 2014 to 8.145 in 2015), its editor was asked to resign. Another editor resigned shortly after.

But last week, Clarivate Analytics named the journal among the top 10 in the field of climate change, as part of its annual Journal Citation Reports.

The annual report also lists a number of journals that have been suppressed from Clarivate’s analysis “due to anomalous citation patterns;” Land Degradation & Development is not listed among the 13 journals this year.

A spokesperson for Clarivate told us:

Continue reading Journal hit by citation scandal named among top in field

Journal flags cancer paper from Karolinska researchers

A journal has issued an expression of concern (EOC) for a 2011 cancer paper, while Karolinska Institutet investigates “concerns” about some of the data.

After the Journal of Cell Science (JCS) received a tip from a reader, it investigated, but was unable to resolve the concerns. So the journal asked KI–where all the authors work–to investigate further, and issued an EOC to alert readers that there may be an issue with the paper.

According to the notice, the questions center on data from Fig. 1A, but the notice does not specify the nature of the concerns. The 2011 paper received a correction in 2016, which cites inadvertent figure duplication.

Earlier this year, the paper’s last author Boris Zhivotovsky and second author Helin Vakifahmetoglu-Norberg retracted a 2008 paper from Oncogene over potential image duplication. That retraction caught our attention because it was prompted by a 2016 correction to the paper, which had raised additional questions about potential duplication; ultimately, the authors retracted both the paper and its correction.

Here’s the expression of concern for the 2011 JCS paper: Continue reading Journal flags cancer paper from Karolinska researchers

Meet PubPeer 2.0: New version of post-publication peer review site launches today

Since it launched in 2012, PubPeer has grown to become a standard part of the scientific lexicon, and its numerous post-publication discussions have led to more editorial notices than we can count. But it’s also faced its share of critics, including a scientist who took the site to court to unmask commenters he alleged had cost him a job offer. The site won that case on appeal, but is today launching new features that will make it impossible for the site to reveal users’ identities, as well as easier to read and format comments. We spoke with PubPeer co-founder Brandon Stell about what to expect from the new site.

Retraction Watch: What changes have you introduced to the site?

Continue reading Meet PubPeer 2.0: New version of post-publication peer review site launches today

Springer purge of fake reviews takes down 10+ more neuroscience papers

Back in April, Springer retracted a record number 107 papers from Tumor Biology after uncovering evidence they were subject to fake peer reviews. But it appears that the Tumor Biology sweep was only part of the story.

During the Tumor Biology investigation, Springer found evidence that the “peer review process was compromised” in a dozen papers on brain cancer published in another journal. The 12 Molecular Neurobiology retractions have trickled in over the past year or so, published before and after the Tumor Biology sweep.

A spokesperson at Springer confirmed that the 12 retracted papers in Molecular Neurobiology were related to the Tumor Biology retractions for fake peer review: Continue reading Springer purge of fake reviews takes down 10+ more neuroscience papers

Quick: What does fish food have to do with X-rays? In this case, an Elsevier production error

An MRI of a fish, not involved in this study. (via Wikimedia)

In 2012, a study claiming to show — after some intentional statistical tricks — that a dead salmon had brain activity in an fMRI won a prestigious (and hilarious) Ig Nobel Prize.

So five years later, when Bálint Botz tweeted wryly about a study of fish and plants in a radiology journal, we thought, “Aha, someone is trying to create another red herring!”

But alas, it turns out the reason a journal normally concerned with X-rays would suddenly be interested in aquaponics was far more prosaic: Continue reading Quick: What does fish food have to do with X-rays? In this case, an Elsevier production error

When a tractor stabs a man in the eye, who gets to write up the case report?

A journal has retracted a paper after the university notified the editors that the authors presented the gruesome details of a patient who they didn’t directly treat.

But the paper’s corresponding author disputes that claim, arguing that the first author — a radiologist, who has since passed away, provided a crucial diagnosis in this case. We’ve tried to track down the doctors who lodged a complaint about the paper, alleging they were “actually involved in the original patient treatment,” but have so far been unsuccessful.

The paper describes an unfortunate accident during which a man fell from his tractor and stabbed himself in the eye on part of the machine. Initially, doctors could not locate the eye and “believed it to have been completely destroyed,” and discharged the patient after seven days. One week later he was back, complaining of headaches — and doctors found the eye embedded deep inside the skull, intact.

According to the retraction notice, issued by the Journal of Neuro-Ophthalmology, an investigation by a university in Iran determined the doctors who initially described the case didn’t have the right to do so: Continue reading When a tractor stabs a man in the eye, who gets to write up the case report?