Researchers have retracted a 2016 paper after discovering that they accidentally administered three times the reported dose of anesthesia to rats.
In the Experimental Physiology paper, the authors set out to mathematically map how rats’ blood pressure changes under different conditions, which required the rats to be anesthetized. But their findings were called into question when they found the rats had received a much higher concentration of anesthesia than intended. According to the notice, this higher dose compromised the “objectives of the experiment.”
The corresponding author Karol Ondrias, from the Institute of Molecular Physiology and Genetics at the Slovak Academy of Sciences in Bratislava, told us how the dosing error occurred: Continue reading Researchers mistakenly administer three-fold higher dose of anesthesia
Karel Bezouška, the Czech biochemist who was caught on hidden camera breaking into a lab fridge to fake results, has turned it up to eleven with two new retractions.
Both retractions appeared in Biochemical and Biophysical Research Communications, one in October 2014 and one in January 2015. His story began two decades ago in 1994, when he published a paper in Nature that couldn’t be reproduced, and was eventually retracted in 2013.
The best part of the story, of course, is that when his university was attempting to recreate his experiments, Bezouška broke into a lab fridge to tamper with the experiments. Unbeknownst to him, he was caught on hidden camera. Continue reading Two more retractions bring lab break-in biochemist up to eleven