Fudged figures sink breast cancer paper

oncogeneA prestigious cancer journal has pulled an article over “concerns” regarding some of the figures, which PubPeer commenters had tagged as suspect.

A few weeks after the paper was published on June 9, comments on PubPeer began accumulating. Commenters called out both potentially manipulated and repeated images. The exact timeline is not clear, because Oncogene does not list a date on the retraction notice, but by August 29 the paper had been retracted.

Here’s the notice for “IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer,” by researchers at Shanghai Jiaotong University School of Medicine and Ruijin Hospital, both in Shanghai, China, and the University of Michigan: Continue reading Fudged figures sink breast cancer paper

87% of bugs resistant to antibiotics? Not so fast, as staph paper yanked after staff mistake

What could have been a truly scary study about drug resistant staph infections in hospitals has been retracted due to a lab error.

6.coverResearchers at a community hospital in Pittsburgh claimed that the commonly quoted 3% rate of staph that is resistant to ceftriaxone and sensitive to methicillin was drastically understated. However, an “honest error in the interpretation of a key lab test” called the findings into question.

Here’s the abstract: Continue reading 87% of bugs resistant to antibiotics? Not so fast, as staph paper yanked after staff mistake

Authors retract PNAS brain genetics paper for statistical issues

pnas 1113The authors of a paper on brain genetics published online in June in the Proceedings of the National Academy of Sciences (PNAS) are retracting it for “a potential confound relating to statistical inference.”

Here’s the notice for “Identification of gene ontologies linked to prefrontal–hippocampal functional coupling in the human brain:” Continue reading Authors retract PNAS brain genetics paper for statistical issues

Tonic-clonic stats error sinks epilepsy paper

pm_cover_dez_01A brain imaging study in children with epilepsy has been retracted by the Journal of Magnetic Resonance Imaging due to a statistics error.

Here’s the notice for “Microstructural Brain Abnormalities of Children of Idiopathic Generalized Epilepsy With Generalized Tonic-Clonic Seizure: A Voxel-Based Diffusional Kurtosis Imaging Study”: Continue reading Tonic-clonic stats error sinks epilepsy paper

Structure fumble sinks second of author’s JACS papers

jacsat_v136i001.inddProof that organic chemistry is hard for everyone, not just pre-meds: A paper in the Journal of the American Chemical Society was retracted after the structures of compounds being studied were “misassigned.”

Another study by author Doo Ok Jang, also in JACS, was retracted in 2013 for the same reason; you can read our coverage here. Jang and Sang Yoon Kim published that one in 2008; the paper we’re talking about today was published in 2010 by Jang and Sung Jun Kim.

Here’s the notice for “Indium-Mediated Catalytic Enantioselective Allylation of N-Benzoylhydrazones Using a Protonated Chiral Amine:” Continue reading Structure fumble sinks second of author’s JACS papers

First author blamed for retraction in prestigious medical journal

jemcoverThe authors of a Journal of Experimental Medicine have retracted it, blaming the first author for data and figure manipulation.

The paper, “The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells,” was initially published in September 2011 and has been cited 25 times, according to Thomson Scientific’s Web of Knowledge. First author Jiyeon Kim was an MD-PhD candidate at the University of Pennsylvania until this year, according to a LinkedIn profile.

Here’s the notice: Continue reading First author blamed for retraction in prestigious medical journal

Authors ask Science to retract Hayabusa asteroid paper

jaxa_logoThe Japan Aerospace Exploration Agency (JAXA) has requested that Science retract a 2006 paper about the makeup of asteroid Itokawa as observed from the spacecraft Hayabusa, the news section of Science reports.

Instead of calibrating their equipment on Earth, the scientists assumed they’d see both magnesium and silicon in the x-ray spectra, and used that assumption to assess the rest of the chemical composition of the asteroid.

The paper may be based on faulty assumptions, but the conclusions have been backed up by other published papers, according to the Science magazine report: Continue reading Authors ask Science to retract Hayabusa asteroid paper

PubPeer Selections: Boosting memory in Science, extending lifespan in Nature, quantum anesthesia in PNAS

pubpeerAs Retraction Watch readers probably know, we’re big fans of PubPeer, the post-publication peer review site that allows comments on papers. Discussions there have led to a number of corrections and retractions, and even more importantly, authors are starting to respond to clarify results, acknowledge errors, or otherwise advance knowledge. After all, as we often note, there’s a long way between raising questions about a study and retracting it.

With all of that in mind, we’re pleased to launch a new weekly post that will be called “PubPeer Selections” in which we’ll highlight featured discussions on PubPeer. Here’s the first installment: Continue reading PubPeer Selections: Boosting memory in Science, extending lifespan in Nature, quantum anesthesia in PNAS

Diabetes researcher Cory Toth now up to nine retractions

neuroscienceCory Toth is up to nine retractions.

The University of Calgary researcher who told us earlier this year that he “will not be publishing in the world of science in the future” has retracted two papers from Neuroscience.

Here’s the notice for “Local erythropoietin signaling enhances regeneration in peripheral axons:” Continue reading Diabetes researcher Cory Toth now up to nine retractions

Second retraction appears for former University of Florida ob-gyn subject to ORI probe

University of Florida
Chegini, via University of Florida

Nasser Chegini, an ob-gyn formerly on the faculty at the University of Florida who has been the subject of an Office of Research Integrity (ORI) inquiry for several years, has a second retraction.

Chegini is suspected of having used bogus data in some of his work — research backed in part by some $4 million in federal funding.

The new retraction involves a 2008 paper in Reproductive Sciences on which Chegini was senior author. Here’s the notice: Continue reading Second retraction appears for former University of Florida ob-gyn subject to ORI probe