Journal takes down autism-vaccine paper pending investigation

translational neurodegenerationAn article purporting to find that black children are at substantially increased risk for autism after early exposure to the measles-mumps-rubella vaccine has been shelved.

Although we don’t know if the events are related, the move comes amid claims that a CDC whistleblower has accused health officials of suppressing information about the link.

Not surprisingly, the prospect that the CDC has been sitting on evidence of an autism-vaccine connection for more than a decade has inflamed the community of activists wrongly convinced that such a link exists.

The paper, “Measles-mumps-rubella vaccination timing and autism among young african american boys: a reanalysis of CDC data,” was written by Brian Hooker, an engineer-turned-biologist and an active member of that community. It was submitted in April, accepted on August 5, and published on August 8.

Translational Neurodegeneration, which published the article earlier this month, has now removed it and posted the following notice: Continue reading Journal takes down autism-vaccine paper pending investigation

“Irregularities” lead to retraction of paper on delirium

spcarecoverA paper on delirium in older adults has been withdrawn by a geriatric journal, after the clinical hospital notified the journal of problems in the data.

Here’s the notice for “Issues Associated with Delirium Severity Among Older Patients,” which first appeared in BMJ Supportive & Palliative Care: Continue reading “Irregularities” lead to retraction of paper on delirium

Authors retract paper “confirming” that narcolepsy is an autoimmune disease

stmA group of researchers at Stanford and elsewhere is retracting a 2013 paper that another scientist told Nature was “one of the biggest things to happen in the narcolepsy field for some time.”

The Science Translational Medicine paper caused a buzz because it claimed to show that narcolepsy was an autoimmune disease. Here’s the notice: Continue reading Authors retract paper “confirming” that narcolepsy is an autoimmune disease

Nothing to see here: Unreplicable eye paper ends in retraction

jneuroimmunoThe authors of a 2012 paper in the Journal of Neuroimmunology have retracted the paper after some of the researchers were unable to verify the findings in follow-up work.

The article, “Association of transforming growth factor beta-1 (TGFB1) regulatory region polymorphisms with myasthenia gravis-related ophthalmoparesis,” came from a lab at Groote Schuur Hospital and the University of Cape Town, in South Africa.

According to the abstract: Continue reading Nothing to see here: Unreplicable eye paper ends in retraction

University of Queensland investigation leads to third retraction

isjplA duo of former University of Queensland researchers have had a third article retracted following an investigation into 92 papers.

In September, Bruce Murdoch and Caroline Barwood had a paper in the European Journal of Neurology retracted. Earlier this month, the same happened to a paper in Aphasiology.

The retraction announced by the university today is for a 2013 paper in the International Journal of Speech-Language Pathology.

Here’s the notice, which is brief and behind a paywall: Continue reading University of Queensland investigation leads to third retraction

NIH/Harvard team loses aging study to manipulated data

agecoverAge has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.

The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.

As the abstract explained: Continue reading NIH/Harvard team loses aging study to manipulated data

Fraud fells Alzheimer’s “made to order” neurons paper in Cell

cell414In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

Continue reading Fraud fells Alzheimer’s “made to order” neurons paper in Cell

Pain study retracted for bogus data is second withdrawal for University of Calgary group

molpainBack in January 2013, we wrote about the retraction of a paper in Diabetes that the authors had “submitted without knowledge of inherent errors or abnormalities that they recognized in retrospect after submission.”

Now, Molecular Pain has retracted a paper by the same authors, this time for data manipulation. The article, “Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states,” was written by Cory Toth, a clinical neuroscientist at the University of Calgary, in Canada, and colleagues. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

Toth said of the Diabetes article at the time:
Continue reading Pain study retracted for bogus data is second withdrawal for University of Calgary group

MS paper second to fall following University of Queensland investigation

aphasiologyTwo former University of Queensland researchers have lost another paper following an investigation into their work.

In September, the university announced that a paper in the European Journal of Neurology by Bruce Murdoch and Caroline Barwood would be retracted because

no primary data can be located, and no evidence has been found that the study described in the article was conducted.

The university continued its investigation, and announced today that: Continue reading MS paper second to fall following University of Queensland investigation

Biotech company retracts Parkinson’s treatment study after “possible deviation from protocol”

LCTLiving Cell Technologies (LCT), a biotech company headquartered in Australia, has retracted a 2011 paper purporting to show that their product reversed Parkinson’s symptoms in rats after “being unable to reconfirm their reported results and a possible deviation from the protocol.”

LCT is developing NTCELL, which, according to their site: Continue reading Biotech company retracts Parkinson’s treatment study after “possible deviation from protocol”